Imperial College London

DR ANDRE F S AMARAL

Faculty of MedicineNational Heart & Lung Institute

Lecturer
 
 
 
//

Contact

 

+44 (0)20 7594 7940a.amaral Website

 
 
//

Location

 

G48Emmanuel Kaye BuildingRoyal Brompton Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Allwood:2020:10.5588/ijtld.20.0067,
author = {Allwood, B and van, der Zalm M and Amaral, A and Byrne, A and Datta, S and Egere, U and Evans, C and Evans, D and Gray, D and Hoddinott, G and Ivanova, O and Jones, R and Makanda, G and Marx, F and Meghji, J and Mpagama, S and Pasipanodya, J and Rachow, A and Schoeman, I and Shaw, J and Stek, C and van, Kampen S and von, Delft D and Walker, N and Wallis, R and Mortimer, K},
doi = {10.5588/ijtld.20.0067},
journal = {International Journal of Tuberculosis and Lung Disease},
pages = {820--828},
title = {Post-tuberculosis lung health: perspectives from the firstInternational symposium},
url = {http://dx.doi.org/10.5588/ijtld.20.0067},
volume = {24},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Tuberculosis, although curable, frequently leaves the individual with chronic physical and psycho-social impairment, yet these consequences have to-date been largely neglected. The 1st International Post-Tuberculosis Symposium was devoted entirely to impairment after tuberculosis, and covered a number of multi-disciplinary topics. Using the Delphi process, consensus was achieved for the terms “post-tuberculosis”, “post-tuberculosis lung disease/s (PTLD)”, and “post-tuberculosis economic, social and psychological well-being” (Post-TB ESP)”, to overcome the historical challenge of varied terminology in the literature. A minimum case-definition was proposed by consensus for PTLD in adults and children. Lack of sufficient evidence hampered definitive recommendations in most domains, including prevention and treatment of PTLD, but highlighted the dire need for research and priorities were identified. The heterogeneity of respiratory outcomes and previously employed research methodologies complicates the accurate estimation of disease burden. However, consensus was reached proposing a toolkit for future PTLD measurement, and on PTLD patterns to be considered. The importance of extra-pulmonary consequences and progressive impairment throughout the life-course was identified, including tuberculosis recurrence and increased mortality. Patient advocates emphasised the need for addressing the psychological and social impacts post tuberculosis, and called for clinical guidance. Increased awareness and more research addressing post-tuberculosis complications is urgently needed.
AU - Allwood,B
AU - van,der Zalm M
AU - Amaral,A
AU - Byrne,A
AU - Datta,S
AU - Egere,U
AU - Evans,C
AU - Evans,D
AU - Gray,D
AU - Hoddinott,G
AU - Ivanova,O
AU - Jones,R
AU - Makanda,G
AU - Marx,F
AU - Meghji,J
AU - Mpagama,S
AU - Pasipanodya,J
AU - Rachow,A
AU - Schoeman,I
AU - Shaw,J
AU - Stek,C
AU - van,Kampen S
AU - von,Delft D
AU - Walker,N
AU - Wallis,R
AU - Mortimer,K
DO - 10.5588/ijtld.20.0067
EP - 828
PY - 2020///
SN - 1027-3719
SP - 820
TI - Post-tuberculosis lung health: perspectives from the firstInternational symposium
T2 - International Journal of Tuberculosis and Lung Disease
UR - http://dx.doi.org/10.5588/ijtld.20.0067
UR - https://www.ingentaconnect.com/content/iuatld/ijtld/2020/00000024/00000008/art00011;jsessionid=5j4jlg9ct8a95.x-ic-live-03
UR - http://hdl.handle.net/10044/1/80102
VL - 24
ER -