Imperial College London

ProfessorAndrewAmis

Faculty of EngineeringDepartment of Mechanical Engineering

Professor
 
 
 
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Contact

 

+44 (0)20 7594 7062a.amis

 
 
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Assistant

 

Ms Fabienne Laperche +44 (0)20 7594 7033

 
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Location

 

713City and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

443 results found

Halewood C, Lumpaopong P, Stephen JM, Amis AAet al., 2015, Functional Biomechanics with Cadaver Specimens, Experimental Research Methods in Orthopedics and Trauma, Editors: Simpson, Augat, Publisher: Thieme Medical Publishers, ISBN: 9783131731111

This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery.

Book chapter

van Arkel RJ, Pal B, Darton H, Amis Aet al., 2015, Biomechanics of Joints, Experimental Research Methods in Orthopedics and Trauma, Editors: Simpson, Augat, Publisher: Thieme Medical Publishers, ISBN: 9783131731111

This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery.

Book chapter

Halewood C, Amis AA, 2015, Clinically relevant biomechanics of the knee capsule and ligaments, Knee Surgery, Sports Traumatology, Arthroscopy, Vol: 23, Pages: 2789-2796, ISSN: 0942-2056

The paper describes the concepts of primary and secondary restraints to knee joint stability and explains systematically how the tibia is stabilised against translational forces and rotational torques in different directions and axes, and how those vary across the arc of flexion–extension. It also shows how the menisci act to stabilise the knee, in addition to load carrying across the joint. It compares the properties of the natural stabilising structures with the strength and stiffness of autogenous tissue grafts and relates those strengths to the strength of graft fixation devices. A good understanding of the biomechanical behaviour of these various structures in the knee will help the surgeon in the assessment and treatment of single and multi-ligament injuries.

Journal article

van Arkel RJ, Amis AA, Cobb JP, Jeffers JRTet al., 2015, The capsular ligaments provide more hip rotational restraint than the acetabular labrum and the ligamentum teres, Bone & Joint Journal, Vol: 97B, Pages: 484-491, ISSN: 2049-4394

In this in vitro study of the hip joint we examined which soft tissues act as primary and secondary passive rotational restraints when the hip joint is functionally loaded. A total of nine cadaveric left hips were mounted in a testing rig that allowed the application of forces, torques and rotations in all six degrees of freedom. The hip was rotated throughout a complete range of movement (ROM) and the contributions of the iliofemoral (medial and lateral arms), pubofemoral and ischiofemoral ligaments and the ligamentum teres to rotational restraint was determined by resecting a ligament and measuring the reduced torque required to achieve the same angular position as before resection. The contribution from the acetabular labrum was also measured. Each of the capsular ligaments acted as the primary hip rotation restraint somewhere within the complete ROM, and the ligamentum teres acted as a secondary restraint in high flexion, adduction and external rotation. The iliofemoral lateral arm and the ischiofemoral ligaments were primary restraints in two-thirds of the positions tested. Appreciation of the importance of these structures in preventing excessive hip rotation and subsequent impingement/instability may be relevant for surgeons undertaking both hip joint preserving surgery and hip arthroplasty.

Journal article

Stephen JM, Halewood C, Kittl C, Bollen S, Williams A, Amis AAet al., 2015, The influence of posterior medial meniscocapsular lesions on tibiofemoral joint laxity in ACL deficient and reconstructed knees, British Association of Surgery of the Knee

Conference paper

Kawaguchi Y, Kondo E, Takeda R, Akita K, Yasuda K, Amis AAet al., 2015, The Role of Fibers in the Femoral Attachment of the Anterior Cruciate Ligament in Resisting Tibial Displacement, ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, Vol: 31, Pages: 435-444, ISSN: 0749-8063

Journal article

Kittl C, Halewood C, Stephen JM, Gupte CM, Weiler A, Williams A, Amis AAet al., 2015, Length Change Patterns in the Lateral Extra-articular Structures of the Knee and Related Reconstructions, AMERICAN JOURNAL OF SPORTS MEDICINE, Vol: 43, Pages: 354-362, ISSN: 0363-5465

Journal article

Stephen JM, Kittl C, Williams A, Marcheggiani Muccioli GM, Zaffagnini S, Fink C, Amis AAet al., 2015, The effect of graft type and femoral positioning on patellofemoral contact pressure and kinematics after medial patellofemoral ligament reconstruction, British Association for Surgery of the Knee

Conference paper

Geraldes D, Hansen U, Amis A, 2015, Parametric analysis of glenoid implant design, European Society of Biomechanics 2015

Conference paper

Gregory TM, Sukjamsri C, Hansen U, Amis AA, Emery R, Augereau Bet al., 2015, Glenoid Aseptic Loosening After Anatomical Shoulder Replacement: a Systematic Review of the Radiolucent Line Significance and of the Loosening Mechanisms, E-MEMOIRES DE L ACADEMIE NATIONALE DE CHIRURGIE, Vol: 14, Pages: 7-12, ISSN: 1634-0647

Journal article

Bonner TJ, Newell N, Karunaratne A, Pullen AD, Amis AA, Bull AMJ, Masouros SDet al., 2015, Strain-rate sensitivity of the lateral collateral ligament of the knee, JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, Vol: 41, Pages: 261-270, ISSN: 1751-6161

Journal article

Keller R, Amis AA, 2015, Anatomy and Biomechanics of the Natural Knee and After TKR, The Unhappy Total Knee Replacement, Editors: Hirschmann, Becker, Publisher: Springer, Pages: 3-15, ISBN: 978-3-319-08098-7

This book addresses the need for improved diagnostic and treatment guidelines for patients in whom total knee arthroplasty (TKA) has had an unsatisfactory outcome. It opens by discussing the basics of TKA and the various causes of failure and pain. Diagnostic aspects are considered in detail, with attention to advances in clinical investigation, laboratory analysis and in particular, imaging techniques. In addition, helpful state of the art diagnostic algorithms are presented. Specific pathology-related treatment options, including conservative approaches and salvage and revision TKA strategies, are then explained, with identification of pitfalls and key points. A series of illustrative cases cover clinical scenarios frequently encountered in daily clinical practice. The evidence-based, clinically focused guidance provided in this book, written by internationally renowned experts, will assist surgeons in achieving the most effective management of these challenging cases.

Book chapter

Puthumanapully PK, Harris SJ, Leong A, Cobb JP, Amis AA, Jeffers Jet al., 2014, A morphometric study of normal and varus knees, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 2891-2899, ISSN: 0942-2056

Journal article

Halewood C, Risebury M, Thomas NP, Amis AAet al., 2014, Kinematic behaviour and soft tissue management in guided motion total knee replacement, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 3074-3082, ISSN: 0942-2056

Journal article

Hunt NC, Ghosh KM, Athwal KK, Longstaff LM, Amis AA, Deehan DJet al., 2014, Lack of evidence to support present medial release methods in total knee arthroplasty, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 3100-3112, ISSN: 0942-2056

Journal article

Stephen JM, Lumpaopong P, Dodds AL, Williams A, Amis AAet al., 2014, The effect of progressive tibial tuberosity medialisation and lateralisation on patellofemoral joint kinematics, contact mechanics and stability, American Journal of Sports Medicine, Vol: 43, Pages: 186-194, ISSN: 1552-3365

Background: Tibial tuberosity (TT) transfer is a common procedure to treat patellofemoral instability in patients with elevated TT–trochlear groove (TG) distances. However, the effects of TT lateralization or medialization on patellar stability, kinematics, and contact mechanics remain unclear.Hypothesis: Progressive medialization and lateralization will have increasingly adverse effects on patellofemoral joint kinematics, contact mechanics, and stability.Study Design: Controlled laboratory study.Methods: Eight fresh-frozen cadaveric knees were placed on a testing rig, with a fixed femur and tibia mobile through 90° of flexion. Individual quadriceps heads and the iliotibial band were separated and loaded with 205 N in anatomic directions using a weighted pulley system. Patellofemoral contact pressures and patellar tracking were measured at 0°, 10°, 20°, 30°, 60°, and 90° of flexion using pressure-sensitive film behind the patella and an optical tracking system. The intact knee was measured with and without a 10-N patellar lateral displacement load, and recordings were repeated after TT transfer of 5, 10, and 15 mm medially and laterally. Statistical analysis used repeated-measures analysis of variance, Bonferroni post hoc analysis, and Pearson correlations.Results: Tibial tuberosity lateralization significantly elevated lateral joint contact pressures, increased lateral patellar tracking, and reduced patellar stability (P < .048). There was a significant correlation between mean lateral contact pressure and the TT position (r = 0.810, P < .001) at 10°. Tibial tuberosity medialization reduced lateral contact pressures (P < .002) and did not elevate peak medial contact pressures (P > .11).Conclusion: Progressive TT lateralization elevated lateral contact pressures, increased lateral patellar tracking, and reduced patellar stability. Medial contact pressure and tracking did alter with progressive TT medialization, but t

Journal article

Barcellona MG, Morrissey MC, Milligan P, Amis AAet al., 2014, The effect of thigh muscle activity on anterior knee laxity in the uninjured and anterior cruciate ligament-injured knee, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 2821-2829, ISSN: 0942-2056

Journal article

Geraldes D, Hansen U, Amis A, 2014, A framework for parametric analysis of glenoid implant design, MECBioengineering 2014

Conference paper

Geraldes D, Hansen U, Jeffers J, Amis Aet al., 2014, A framework for parametric analysis of glenoid implant design, International Society for Technology in Arthroplasty 2014

Conference paper

Tuncer M, Hansen UN, Amis AA, 2014, Prediction of structural failure of tibial bone models under physiological loads: Effect of CT density-modulus relationships, MEDICAL ENGINEERING & PHYSICS, Vol: 36, Pages: 991-997, ISSN: 1350-4533

Journal article

Ghosh KM, Blain AP, Longstaff L, Rushton S, Amis AA, Deehan DJet al., 2014, Can we define envelope of laxity during navigated knee arthroplasty?, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 1736-1743, ISSN: 0942-2056

Journal article

Kittl C, Weiler A, Amis AA, 2014, Anterolateral rotatory instability: Anatomy, biomechanics, and reconstruction, Arthroskopie, Vol: 27, Pages: 170-176, ISSN: 0933-7946

Background: Anterolateral rotatory instability (ALRI) of the knee consists of a translational and rotational component. It is widely accepted that anterior cruciate ligament (ACL) deficiency causes anterior tibial translation, but controversy exists regarding the peripheral structures restraining tibial internal rotation. These structures may be reconstructed using lateral extra-articular soft-tissue reconstruction. The principal behind these types of reconstruction is to tether the graft posterior to the transverse center of rotation, therefore, limiting internal tibial rotation and ultimately restraining the rotational component of the pivot shift test. Aim: The aim of the following paper is to provide a critical literature review regarding anatomy, biomechanics, and related types of reconstruction of the anterolateral side of the knee. Materials and methods: The article provides a critical review of the ALRI literature and takes into account the authors' own anatomical and biomechanical observations. Results: Based on this literature review, the anterolateral structures of the knee may be more important in restraining internal tibial rotation than previously thought. Conclusion: A combined intra-articular ACL and lateral extra-articular soft-tissue reconstruction may be desirable in revision ACL surgery and in patients presenting excessive ALRI following ACL rupture. © 2014 Springer-Verlag Berlin Heidelberg.

Journal article

Amis AA, Arendt E, Deehan D, Defoort DC, Dejour D, Fink C, van Gennip S, Goyal D, Groenen K, van Hellemondt GG, Lentinga A, Lumpaopong P, Kader D, Kampen AV, Koeter S, Rood A, Schimmel JJ, Schoetlle P, Stephen JM, Verdonschot N, Wymenga ABet al., 2014, The Medial Patellofemoral Ligament, Publisher: Springer Berlin Heidelberg

Book

Halewood C, Samuelsson K, Kopf S, Alentorn-Geli E, Musahl Vet al., 2014, How to do proper research, ESSKA Instructional Course Lecture Book Amsterdam 2014, Publisher: Springer, ISBN: 9783642539824

This book provides an update on a wide variety of hot topics in the field of knee surgery, sports trauma and arthroscopy, covering the latest developments in basic science and clinical and surgical methods.

Book chapter

Atallah L, Wiik A, Lo B, Cobb JP, Amis AA, Yang G-Zet al., 2014, Gait asymmetry detection in older adults using a light ear-worn sensor, PHYSIOLOGICAL MEASUREMENT, Vol: 35, Pages: N29-N40, ISSN: 0967-3334

Journal article

Gupte CM, Schaerf DA, Sandison A, Bull AMJ, Amis AAet al., 2014, Neural Structures within Human Meniscofemoral Ligaments: A Cadaveric Study., ISRN Anatomy, Vol: 2014, ISSN: 2314-4726

Aim. To investigate the existence of neural structures within the meniscofemoral ligaments (MFLs) of the human knee. Methods. The MFLs from 8 human cadaveric knees were harvested. 5 μm sections were H&E-stained and examined under light microscopy. The harvested ligaments were then stained using an S100 monoclonal antibody utilising the ABC technique to detect neural components. Further examination was performed on 60–80 nm sections under electron microscopy. Results. Of the 8 knees, 6 were suitable for examination. From these both MFLs existed in 3, only anterior MFLs were present in 2, and an isolated posterior MFL existed in 1. Out of the 9 MFLs, 4 demonstrated neural structures on light and electron microscopy and this was confirmed with S100 staining. The ultrastructure of these neural components was morphologically similar to mechanoreceptors. Conclusion. Neural structures are present in MFLs near to their meniscal attachments. It is likely that the meniscofemoral ligaments contribute not only as passive secondary restraints to posterior draw but more importantly to proprioception and may therefore play an active role in providing a neurosensory feedback loop. This may be particularly important when the primary restraint has reduced function as in the posterior cruciate ligament—deficient human knee.

Journal article

Newman SD, Lotfibakhshaiesh N, O'Donnell M, Walboomers XF, Horwood N, Jansen JA, Amis AA, Cobb JP, Stevens MMet al., 2014, Enhanced Osseous Implant Fixation with Strontium-Substituted Bioactive Glass Coating, TISSUE ENGINEERING PART A, Vol: 20, Pages: 1850-1857, ISSN: 1937-3341

The use of endosseous implants is firmly established in skeletal reconstructive surgery, with rapid and permanent fixation of prostheses being a highly desirable feature. Implant coatings composed of hydroxyapatite (HA) have become the standard and have been used with some success in prolonging the time to revision surgery, but aseptic loosening remains a significant issue. The development of a new generation of more biologically active coatings is a promising approach for tackling this problem. Bioactive glasses are an ideal candidate material due to the osteostimulative properties of their dissolution products. However, to date, they have not been formulated with stability to devitrification or thermal expansion coefficients (TECs) that are suitable for stable coating onto metal implants while still retaining their bioactive properties. Here, we present a strontium-substituted bioactive glass (SrBG) implant coating which has been designed to encourage peri-implant bone formation and with a TEC similar to that of HA. The coating can be successfully applied to roughened Ti6Al4V and after implantation into the distal femur and proximal tibia of twenty-seven New Zealand White rabbits for 6, 12, or 24 weeks, it produced no adverse tissue reaction. The glass dissolved over a 6 week period, stimulating enhanced peri-implant bone formation compared with matched HA coated implants in the contralateral limb. Furthermore, superior mechanical fixation was evident in the SrBG group after 24 weeks of implantation. We propose that this coating has the potential to enhance implant fixation in a variety of orthopedic reconstructive surgery applications.

Journal article

Kondo E, Merican AM, Yasuda K, Amis AAet al., 2014, Biomechanical Analysis of Knee Laxity With Isolated Anteromedial or Posterolateral Bundle-Deficient Anterior Cruciate Ligament, ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, Vol: 30, Pages: 335-343, ISSN: 0749-8063

Journal article

Dodds AL, Halewood C, Gupte CM, Williams A, Amis AAet al., 2014, The anterolateral ligament ANATOMY, LENGTH CHANGES AND ASSOCIATION WITH THE SEGOND FRACTURE, BONE & JOINT JOURNAL, Vol: 96B, Pages: 325-331, ISSN: 2049-4394

Journal article

Stoddard JE, Deehan DJ, Bull AMJ, McCaskie AW, Amis AAet al., 2014, No difference in patellar tracking between symmetrical and asymmetrical femoral component designs in TKA, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol: 22, Pages: 534-542, ISSN: 0942-2056

Journal article

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