Imperial College London

ProfessorAndrewAmis

Faculty of EngineeringDepartment of Mechanical Engineering

Professor
 
 
 
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Contact

 

+44 (0)20 7594 7062a.amis

 
 
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Assistant

 

Ms Fabienne Laperche +44 (0)20 7594 7033

 
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Location

 

713City and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Colaco:2017:10.1016/j.jbiomech.2017.01.011,
author = {Colaco, H and Lord, BR and Back, DL and Davies, AJ and Amis, AA and Ajuied, A},
doi = {10.1016/j.jbiomech.2017.01.011},
journal = {Journal of Biomechanics},
pages = {144--147},
title = {Biomechanical properties of Bovine tendon xenografts treated with a modern processing method},
url = {http://dx.doi.org/10.1016/j.jbiomech.2017.01.011},
volume = {53},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Xenograft tendons have been used in few human studies, with variable results. With the advent of novel tissue processing techniques, which may mitigate against an immune-mediated rejection response without adversely affecting mechanical properties, there maynowbe a clinical role for xenograft tendons, particularly in knee ligament reconstruction. We hypothesize that‘BioCleanse®’processed bovine extensor digitorum medialis(EDM) tendons exhibit favorable time-zero pre-implantation biomechanical characteristics when compared to both unprocessed bovine EDM tendons and BioCleanse® processed human cadaveric allograft tibialis anterior tendons.In this in vitrocase controlled laboratory study, three groups of tendons underwent a 5-stage static loading test protocol: 15 BioCleanse® bovine (BCB), 15 fresh frozen unprocessed bovine (FFB), and 12 BioCleanse® human allograft (BCA) tendons. Cross-sectional area of the grafts was measured using an alginate molding technique, and tendons were mounted within an Instron® 5565 Materials Testing System using cryogenic clamps. BCB tendons displayed a higher ultimate tensile stress (p<0.05), with equivalent ultimate failure load, creep, and modulus of elasticity when compared to the FFB tendons (p>0.05). BCB tendons had an equivalent cross-sectional area to the BCA tendons (p>0.05) whilst exhibiting a greater failure load, ultimate tensile stress, less creep and a higher modulus of elasticity (p<0.05).The BioCleanse® process didnot adversely affect the time-zero biomechanical roperties of bovine xenograft EDM tendons. BioCleanse® processed bovine xenograft EDM tendons exhibitedsuperior biomechanical characteristics when 3compared with BioCleanse® processed allograft tibialis anterior tendons
AU - Colaco,H
AU - Lord,BR
AU - Back,DL
AU - Davies,AJ
AU - Amis,AA
AU - Ajuied,A
DO - 10.1016/j.jbiomech.2017.01.011
EP - 147
PY - 2017///
SN - 1873-2380
SP - 144
TI - Biomechanical properties of Bovine tendon xenografts treated with a modern processing method
T2 - Journal of Biomechanics
UR - http://dx.doi.org/10.1016/j.jbiomech.2017.01.011
UR - http://hdl.handle.net/10044/1/43976
VL - 53
ER -