Imperial College London


Faculty of EngineeringDepartment of Mechanical Engineering




+44 (0)20 7594 7062a.amis




Ms Fabienne Laperche +44 (0)20 7594 7033




713City and Guilds BuildingSouth Kensington Campus






BibTex format

author = {Halewood, C and Athwal, KK and Amis, A},
doi = {10.1016/j.jbiomech.2018.03.042},
journal = {Journal of Biomechanics},
pages = {153--160},
title = {Pre-clinical assessment of total knee replacement anterior-posterior constraint},
url = {},
volume = {73},
year = {2018}

RIS format (EndNote, RefMan)

AB - Pre-clinical, bench-top assessment of Total Knee Replacements (TKR) can provide information about the inherent constraint provided by a TKR, which does not depend on the condition of the patient undergoing the arthroplasty. However little guidance is given by the ASTM standard on test configurations such as medial-lateral (M:L) loading distribution, flexion angle or restriction of secondary motions. Using a purpose built rig for a materials testing machine, four TKRs currently in widespread clinical use, including medial-pivot and symmetrical condyle types, were tested for anterior-posterior translational constraint. Compressive joint loads from 710 to 2000N, and a range of medial-lateral (M:L) load distributions, from 70:30% to 30:70% M:L, were applied at different flexion angles with secondary motions unconstrained. It was found that TKA constraint was significantly less at 60 and 90° flexion than at 0°, whilst increasing the compressive joint load increased the force required to translate the tibia to limits of AP constraint at all flexion angles tested. Additionally when M:L load distribution was shifted medially, a coupled internal rotation was observed with anterior translation and external rotation with posterior translation. This paper includes some recommendations for future development of pre-clinical testing methods.
AU - Halewood,C
AU - Athwal,KK
AU - Amis,A
DO - 10.1016/j.jbiomech.2018.03.042
EP - 160
PY - 2018///
SN - 0021-9290
SP - 153
TI - Pre-clinical assessment of total knee replacement anterior-posterior constraint
T2 - Journal of Biomechanics
UR -
UR -
VL - 73
ER -