Imperial College London

ProfessorAndrewAmis

Faculty of EngineeringDepartment of Mechanical Engineering

Professor
 
 
 
//

Contact

 

+44 (0)20 7594 7062a.amis

 
 
//

Assistant

 

Ms Fabienne Laperche +44 (0)20 7594 7033

 
//

Location

 

713City and Guilds BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Kanca:2018:10.1016/j.jmbbm.2018.04.001,
author = {Kanca, Y and Milner, P and Dini, D and Amis, A},
doi = {10.1016/j.jmbbm.2018.04.001},
journal = {Journal of the Mechanical Behavior of Biomedical Materials},
pages = {394--402},
title = {Tribological evaluation of biomedical polycarbonate urethanes against articular cartilage},
url = {http://dx.doi.org/10.1016/j.jmbbm.2018.04.001},
volume = {82},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - This research investigated the in-vitro wear and friction performance of polycarbonate urethane (PCU) 80A as they interact with articular cartilage, using a customised multidirectional pin-on-plate tester. Condyles were articulated against PCU 80A discs (Bionate® I and Bionate® II) (configuration 1) and the results arising from these tests were compared to those recorded during the sliding of PCU pins against cartilage plates (configuration 2). Configuration 1 produced steadily increasing coefficient of friction (COF) (up to 0.64±0.05) and had the same trend as the cartilage–on–stainless steel articulation (positive control). When synovial fluid rather than bovine calf serum was used as lubricant, average COF significantly decreased from 0.50±0.02–0.38±0.06 for condyle–on–Bionate® I (80AI) and from 0.41±0.02–0.24±0.04 for condyle–on–Bionate® II (80AII) test configurations (p<0.05). After 15h testing, the cartilage–on–cartilage articulation (negative control) tests showed no cartilage degeneration. However, different levels of cartilage volume loss were found on the condyles from the positive control (12.5±4.2mm3) and the PCUs (20.1±3.6mm3 for 80AI and 19.0±2.3 mm3 for 80AII) (p>0.05). A good correlation (R2 =0.84) was found between the levels of average COF and the volume of cartilage lost during testing; increasing wear was found at higher levels of COF. Configuration 2 showed low and constant COF values (0.04±0.01), which were closer to the negative control (0.03±0.01) and significantly lower than configuration 1 (p<0.05). The investigation showed that PCU is a good candidate for use in hemiarthroplasty components, where only one of the two articulating surfaces is replaced, as long as the synthetic material is implanted in a region where migrating cartilage contact is achieved. Bio
AU - Kanca,Y
AU - Milner,P
AU - Dini,D
AU - Amis,A
DO - 10.1016/j.jmbbm.2018.04.001
EP - 402
PY - 2018///
SN - 1751-6161
SP - 394
TI - Tribological evaluation of biomedical polycarbonate urethanes against articular cartilage
T2 - Journal of the Mechanical Behavior of Biomedical Materials
UR - http://dx.doi.org/10.1016/j.jmbbm.2018.04.001
UR - https://www.sciencedirect.com/science/article/pii/S1751616118304326
UR - http://hdl.handle.net/10044/1/60918
VL - 82
ER -