Imperial College London
Portrait Picture

ProfessorAndrewAmis

Faculty of Engineering, Department of Mechanical Engineering

Professor
 
 
 
//

Contact

 

+44 (0)7722 225 409a.amis

 
 
//

Assistant

 

Ms Fabienne Laperche +44 (0)20 7594 7033

 
//

Location

 

713City and Guilds BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Kanca:2017:10.1016/j.jmbbm.2017.10.027,
author = {Kanca, Y and Milner, P and Dini, D and Amis, AA},
doi = {10.1016/j.jmbbm.2017.10.027},
journal = {Journal of the Mechanical Behavior of Biomedical Materials},
pages = {36--45},
title = {Tribological properties of PVA/PVP blend hydrogels against articular cartilage.},
url = {http://dx.doi.org/10.1016/j.jmbbm.2017.10.027},
volume = {78},
year = {2017}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - This research investigated in-vitro tribological performance of the articulation of cartilage-on- polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) blend hydrogels using a custom-designed multi-directional wear rig. The hydrogels were prepared by repeated freezing-thawing cycles at different concentrations and PVA to PVP fractions at a given concentration. PVA/PVP blend hydrogels showed low coefficient of friction (COF) values (between 0.12 ± 0.01 and 0.14 ± 0.02) which were closer to the cartilage-on-cartilage articulation (0.03 ± 0.01) compared to the cartilage-on-stainless steel articulation (0.46 ± 0.06). The COF increased with increasing hydrogel concentration (p = 0.03) and decreasing PVP content at a given concentration (p < 0.05). The cartilage-on-hydrogel tests showed only the surface layers of the cartilage being removed (average volume loss of the condyles was 12.5 ± 4.2mm3). However, the hydrogels were found to be worn/deformed. The hydrogels prepared at a higher concentration showed lower apparent volume loss. A strong correlation (R2 = 0.94) was found between the COF and compressive moduli of the hydrogel groups, resulting from decreasing contact congruency. It was concluded that the hydrogels were promising as hemiarthroplasty materials, but that improved mechanical behaviour was required for clinical use.
AU  - Kanca,Y
AU  - Milner,P
AU  - Dini,D
AU  - Amis,AA
DO  - 10.1016/j.jmbbm.2017.10.027
EP  - 45
PY  - 2017///
SN  - 1751-6161
SP  - 36
TI  - Tribological properties of PVA/PVP blend hydrogels against articular cartilage.
T2  - Journal of the Mechanical Behavior of Biomedical Materials
UR  - http://dx.doi.org/10.1016/j.jmbbm.2017.10.027
UR  - http://hdl.handle.net/10044/1/55419
VL  - 78
ER  -
Download