Imperial College London
Portrait Picture

DrAndyAshley

Faculty of Natural Sciences, Department of Chemistry

Honorary Lecturer
 
 
 
//

Contact

 

+44 (0)20 7594 5810a.ashley Website

 
 
//

Location

 

601LMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Mercea:2019:10.1039/c9cc02900a,
author = {Mercea, DM and Howlett, MG and Piascik, AD and Scott, DJ and Steven, A and Ashley, AE and Fuchter, MJ},
doi = {10.1039/c9cc02900a},
journal = {Chemical Communications},
pages = {7077--7080},
title = {Enantioselective reduction of N-alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions},
url = {http://dx.doi.org/10.1039/c9cc02900a},
volume = {55},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Enantioselective reduction of ketimines was demonstrated using chiral N-heterocyclic carbene (NHC)-stabilised borenium ions in frustrated Lewis pair catalysis. High levels of enantioselectivity were achieved for substrates featuring secondary N-alkyl substituents. Comparative reactivity and mechanistic studies identify key determinants required to achieve useful enantioselectivity and represent a step forward in the further development of enantioselective FLP methodologies.
AU  - Mercea,DM
AU  - Howlett,MG
AU  - Piascik,AD
AU  - Scott,DJ
AU  - Steven,A
AU  - Ashley,AE
AU  - Fuchter,MJ
DO  - 10.1039/c9cc02900a
EP  - 7080
PY  - 2019///
SN  - 1359-7345
SP  - 7077
TI  - Enantioselective reduction of N-alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/c9cc02900a
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31149679
UR  - https://pubs.rsc.org/en/content/articlelanding/2019/CC/C9CC02900A#!divAbstract
UR  - http://hdl.handle.net/10044/1/70396
VL  - 55
ER  -
Download