Imperial College London
Mr Adarsh Babber

MrAdarshBabber

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Research Fellow
 
 
 
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Contact

 

a.babber

 
 
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Location

 

4E16East WingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Babber:2020:10.1002/bjs.11398,
author = {Babber, A and Ravikumar, R and Onida, S and Lane, T and Davies, A},
doi = {10.1002/bjs.11398},
journal = {British Journal of Surgery},
pages = {355--363},
title = {Effect of footplate neuromuscular electrical stimulation on functional and qualityoflife parameters in patients with peripheral artery disease: pilot, and subsequent randomized clinical trial},
url = {http://dx.doi.org/10.1002/bjs.11398},
volume = {107},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundSupervised exercise programmes for intermittent claudication have poor access and limited compliance. Neuromuscular electrical stimulation (NMES) may be an effective alternative. A proofofconcept study and RCT were conducted.MethodsIn study 1, eligible patients underwent baseline assessment; treadmill testing for initial (ICD) and maximum (MCD) claudication distance; EuroQoL Five Dimensions fivelevel instrument (EQ5D5L™) and Intermittent Claudication Questionnaire (ICQ) assessment; and measurement of ultrasound haemodynamics of the superficial femoral artery. After familiarization with the NMES device, participants underwent a 30min session of stimulation with concomitant recording of haemodynamic measures at 15 min, and after device cessation. Measurements were repeated after 6 weeks of daily use of NMES. In study 2, consecutive patients underwent baseline assessment before online randomization to a supervised exercise programme only, or adjunctive NMES treatment for 6 weeks, followed by repeat measurements.ResultsStudy 1 (20 patients) showed a significant improvement in MCD (46 per cent; P < 0·001) and ICD (71 per cent; P < 0·001). The RCT (42 patients) showed a significant adjunctive benefit of NMES in ICD (46 per cent; P = 0·014). Improvements were seen in the ICQ (9 points; P = 0·009) and EQ5D5L™ (P = 0·007) in study 1, and there was a significant adjunctive benefit of NMES on the ICQ score in patients who did supervised exercise (11·2 points; P = 0·031). Blood volume flow and timeadjusted mean velocity increased significantly with the device on (P < 0·050). Overall, NMES compliance exceeded 95 per cent.ConclusionFootplate NMES significantly improved walking distance in patients with intermittent claudication when used independently and also as an ad
AU  - Babber,A
AU  - Ravikumar,R
AU  - Onida,S
AU  - Lane,T
AU  - Davies,A
DO  - 10.1002/bjs.11398
EP  - 363
PY  - 2020///
SN  - 0007-1323
SP  - 355
TI  - Effect of footplate neuromuscular electrical stimulation on functional and qualityoflife parameters in patients with peripheral artery disease: pilot, and subsequent randomized clinical trial
T2  - British Journal of Surgery
UR  - http://dx.doi.org/10.1002/bjs.11398
UR  - http://hdl.handle.net/10044/1/78702
VL  - 107
ER  -
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