Imperial College London

DrAndreaBeaghton

Faculty of Natural SciencesDepartment of Life Sciences (Silwood Park)

Research Fellow in Population Genetics
 
 
 
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Contact

 

a.beaghton

 
 
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Location

 

377ASir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

My research, with Professor Austin Burt, is on reaction-diffusion models of population dynamics and on spatial and temporal evolution and propagation of invading population waveforms. The primary focus is on modelling the usage of selfish genetic elements to genetically manipulate natural populations of mosquitoes that transmit malaria.

Selected Publications

Journal Articles

Simoni A, Hammond AM, Beaghton AK, et al., 2020, A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae, Nature Biotechnology, Vol:38, ISSN:1087-0156, Pages:1054-1060

Beaghton AK, Hammond A, Nolan T, et al., 2019, Gene drive for population genetic control: non-functional resistance and parental effects, Proceedings of the Royal Society B: Biological Sciences, Vol:286, ISSN:0962-8452, Pages:1-8

Nash A, Urdaneta Mignini G, Beaghton A, et al., 2019, Integral Gene Drives for population replacement, Biology Open, Vol:8, ISSN:2046-6390

Kyrou K, Hammond AM, Galizi R, et al., 2018, A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes, Nature Biotechnology, Vol:36, ISSN:1087-0156, Pages:1062-1066

Beaghton AK, Beaghton PJ, Burt A, 2017, Vector control with driving Y chromosomes: modelling the evolution of resistance, Malaria Journal, Vol:16, ISSN:1475-2875

Beaghton A, Hammond A, Nolan T, et al., 2017, Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing, Genetics, Vol:205, Pages:1587-1596

Beaghton A, Beaghton PJ, Burt A, 2016, Gene drive through a landscape: Reaction–diffusion models of population suppression and elimination by a sex ratio distorter, Theoretical Population Biology, Vol:108, ISSN:1096-0325, Pages:51-69

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