Imperial College London
Alternate

Anthony M J Bull FREng

Faculty of Engineering, Department of Bioengineering

Professor of Musculoskeletal Mechanics
 
 
 
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Contact

 

+44 (0)20 7594 5186a.bull Website

 
 
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Location

 

Uren 514aSir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ding:2021:10.1002/jor.24751,
author = {Ding, Z and Jarvis, H and Bennett, A and Baker, R and Bull, A},
doi = {10.1002/jor.24751},
journal = {Journal of Orthopaedic Research},
pages = {850--860},
title = {Higher knee contact forces might underlie increased osteoarthritis rates in high functioning amputees: a pilot study},
url = {http://dx.doi.org/10.1002/jor.24751},
volume = {39},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - High functioning military transtibial amputees (TTAs) with wellfitted state of the art prosthetics have gait that is indistinguishable from healthy individuals, yet they are more likely to develop knee osteoarthritis (OA) of their intact limbs. This contrasts with the information at the knees of the amputated limbs that have been shown to be at a significantly reduced risk of pain and OA. The hypothesis of this study is that biomechanics can explain the difference in knee OA risk. Eleven military unilateral TTAs and eleven matched healthy controls underwent gait analysis. Muscle forces and joint contact forces at the knee were quantified using musculoskeletal modeling, validated using electromyography measurements. Peak knee contact forces for the intact limbs on both the medial and lateral compartments were significantly greater than the healthy controls (P  ≤ .006). Additionally, the intact limbs had greater peak semimembranosus (P  = .001) and gastrocnemius (P  ≤ .001) muscle forces compared to the controls. This study has for the first time provided robust evidence of increased force on the nonaffected knees of high functioning TTAs that supports the mechanically based hypothesis to explain the documented higher risk of knee OA in this patient group. The results suggest several protentional strategies to mitigate knee OA of the intact limbs, which may include the improvements of the prosthetic foot control, socket design, and strengthening of the amputated muscles.
AU  - Ding,Z
AU  - Jarvis,H
AU  - Bennett,A
AU  - Baker,R
AU  - Bull,A
DO  - 10.1002/jor.24751
EP  - 860
PY  - 2021///
SN  - 0736-0266
SP  - 850
TI  - Higher knee contact forces might underlie increased osteoarthritis rates in high functioning amputees: a pilot study
T2  - Journal of Orthopaedic Research
UR  - http://dx.doi.org/10.1002/jor.24751
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/jor.24751
UR  - http://hdl.handle.net/10044/1/80035
VL  - 39
ER  -
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