I completed my undergraduate studies in Chemistry at University College Dublin and subsequently undertook a PhD in medicinal chemistry at the School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin. After a period in industry, I carried out postdoctoral work at Northwestern University, Chicago; this work focused on immune pathways involved in asthma, allergy and anaphylaxis.
In 2011, I joined the laboratories of Prof. Irina Udalova at the University of Oxford and Prof. Clare Lloyd at Imperial College London, in a collaborative project funded by the American Asthma Society entitled “Does IRF5 control allergic airways disease?”. I was appointed as a Lecturer in Chronic Lung Disease at the Inflammation, Repair & Development Section, NHLI in 2016 and was awarded a Joan Bending, Evelyn Bending, Mervyn Stephens Olive Stephens Memorial Fellowship fellowship in 2017. My work aims to understand the role of airway macrophages during chronic lung diseases such as asthma and idiopathic pulmonary fibrosis.
et al., 2023, Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis, Nature Communications, ISSN:2041-1723
et al., 2023, Airway soluble CSF1R predicts progression in patients with idiopathic pulmonary fibrosis., Erj Open Res, Vol:9, ISSN:2312-0541
et al., 2022, CYFRA 21-1 predicts progression in IPF: a prospective longitudinal analysis of the PROFILE cohort, American Journal of Respiratory and Critical Care Medicine, Vol:205, ISSN:1073-449X, Pages:1440-1448
Byrne AJ, Saglani S, Snelgrove RJ, 2022, An Alarmin Role for P2Y(13) Receptor during Viral-driven Asthma Exacerbations, American Journal of Respiratory and Critical Care Medicine, Vol:205, ISSN:1073-449X, Pages:263-265
et al., 2022, Allergen exposure induces airway macrophage metabolic reprogramming, EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936