I completed my undergraduate studies in Chemistry at University College Dublin in 2001 and subsequently undertook a PhD in medicinal chemistry within the group of Dr. John Walsh at the School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin in 2002. After a period in industry, I carried out postdoctoral work at Northwestern University, Chicago; this work focused on immune pathways involved in asthma, allergy and anaphylaxis.
In 2011, I joined the laboratories of Prof. Irina Udalova at the University of Oxford and Prof. Clare Lloyd at Imperial College London, in a collaborative project funded by the American Asthma Society entitled “Does IRF5 control allergic airways disease?”. I was appointed as a Lecturer in Chronic Lung Disease at the Inflammation, Repair & Development Section, NHLI in 2016 and was awarded a Joan Bending, Evelyn Bending, Mervyn Stephens Olive Stephens Memorial Fellowship fellowship in 2017. My work focuses on the role of alveolar macrophages in asthma and idiopathic pulmonary fibrosis.
et al., Dynamics of human monocytes and airway macrophages during healthy aging and post-transplant, Journal of Experimental Medicine, ISSN:0022-1007
et al., 2019, Modelling forced vital capacity in idiopathic pulmonary fibrosis: optimising trial design., Advances in Therapy, Vol:36, ISSN:0741-238X, Pages:3059-3070
et al., 2019, Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis, Science Translational Medicine, Vol:11, ISSN:1946-6234, Pages:1-14
Byrne AJ, Reply to: CD71-Alveolar Macrophages in IPF: a Look Beyond the Borders of the Disease., Am J Respir Crit Care Med
et al., 2019, The transferrin receptor CD71 delineates functionally distinct airway macrophage subsets during idiopathic pulmonary fibrosis, American Journal of Respiratory and Critical Care Medicine, Vol:200, ISSN:1073-449X