I completed my undergraduate studies in Chemistry at University College Dublin in 2001 and subsequently undertook a PhD in medicinal chemistry within the group of Dr. John Walsh at the School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin in 2002. After a period in industry, I carried out postdoctoral work at Northwestern University, Chicago; this work focused on immune pathways involved in asthma, allergy and anaphylaxis.
In 2011, I joined the laboratories of Prof. Irina Udalova at the University of Oxford and Prof. Clare Lloyd at Imperial College London, in a collaborative project funded by the American Asthma Society entitled “Does IRF5 control allergic airways disease?”. I was appointed as a Lecturer in Chronic Lung Disease at the Inflammation, Repair & Development Section, NHLI in 2016 and was awarded an Asthma UK senior fellowship in 2017. My work focuses on the role of alveolar macrophages in asthma and idiopathic pulmonary fibrosis.
et al., 2019, The transferrin receptor CD71 delineates functionally distinct airway macrophage subsets during idiopathic pulmonary fibrosis, American Journal of Respiratory and Critical Care Medicine, ISSN:1073-449X
et al., 2019, Histamine-driven responses are sustained via a bioactive metabolite, Journal of Allergy and Clinical Immunology, ISSN:0091-6749
Saglani S, 2018, Inception of early life allergen induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells, Science Immunology, Vol:3, ISSN:2470-9468
et al., 2019, Lentivirus Gene Therapy for Autoimmune Pulmonary Alveolar Proteinosis, 22nd Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), CELL PRESS, Pages:43-44, ISSN:1525-0016
et al., 2019, IL-11 Is a Therapeutic Target in Idiopathic Pulmonary Fibrosis, International Conference of the American-Thoracic-Society, AMER THORACIC SOC, ISSN:1073-449X