Publications
687 results found
Gore RB, Smith AM, Smillie F, et al., 2001, Mutant HDM allergen rDer p 2 (C21/73S) elicits proliferative T-cell responses similar to natural nDer p 2 and to rDer p 2 (D1S), Publisher: BLACKWELL SCIENCE LTD, Pages: 156-156, ISSN: 0954-7894
Woodcock A, Custovic A, 2000, Allergen avoidance, SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT, Vol: 130, Pages: 1903-1908, ISSN: 0036-7672
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- Citations: 1
Green RM, Custovic A, Sanderson G, et al., 2000, Prospective case-control study of adults admitted to hospital with acute asthma., THORAX, Vol: 55, Pages: A3-A3, ISSN: 0040-6376
Fryer AA, Spiteri MA, Bianco A, et al., 2000, The-403 G→A promoter polymorphism in the RANTES gene is associated with atopy and asthma, GENES AND IMMUNITY, Vol: 1, Pages: 509-514, ISSN: 1466-4879
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- Citations: 98
Hadi EA, Gore RB, Craven M, et al., 2000, House dust mite allergen levels: Reservoir house dust and intra-nasal sampling, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: A32-A32, ISSN: 0040-6376
Asher I, Boner A, Chuchalin A, et al., 2000, Prevention of allergy and asthma: interim report., Allergy, Vol: 55, Pages: 1069-1088, ISSN: 0105-4538
Johansson SGO, Haahtela T, Asher I, et al., 2000, Prevention of Allergy and Asthma Interim Report - Based on the WHO/IAACI Meeting on the Primary Prevention of Allergy and Asthma - 5-6 December 1999 - Geneva, Switzerland, ALLERGY, Vol: 55, Pages: 1069-1085, ISSN: 0105-4538
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- Citations: 22
Brutsche MH, Brutsche IC, Munavvar M, et al., 2000, Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: a randomised crossover study, LANCET, Vol: 356, Pages: 556-561, ISSN: 0140-6736
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- Citations: 183
Custovic A, Woodcock A, 2000, Clinical effects of allergen avoidance, CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, Vol: 18, Pages: 397-419, ISSN: 1080-0549
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- Citations: 12
Custovic A, Hallam C, Woodcock H, et al., 2000, Synthetic pillows contain higher levels of cat and dog allergen than feather pillows, PEDIATRIC ALLERGY AND IMMUNOLOGY, Vol: 11, Pages: 71-73, ISSN: 0905-6157
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- Citations: 24
Custovic A, Simpson BM, Simpson A, et al., 2000, Manchester Asthma and Allergy Study: Low-allergen environment can be achieved and maintained during pregnancy and in early life, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 105, Pages: 252-258, ISSN: 0091-6749
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- Citations: 150
Høst A, Boner A, Odhiambo J, et al., 2000, Chapter 4: Preventive measures, Allergy and Clinical Immunology International, Vol: 12, Pages: 296-299, ISSN: 0838-1925
Asher I, Boner A, Chuchalin A, et al., 2000, Prevention of allergy and asthma interim report based on the WHO/IAACI meeting on the primary prevention of allergy and asthma, Allergy: European Journal of Allergy and Clinical Immunology, Vol: 55, Pages: 1069-1073, ISSN: 0105-4538
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- Citations: 19
Custovic A, Simpson BM, Simpson A, et al., 2000, Manchester Asthma and Allergy Study: Low-allergen environment can be achieved and maintained during pregnancy and in early life, Journal of Allergy and Clinical Immunology, Vol: 105, Pages: 252-258, ISSN: 0091-6749
Background: Early exposure to dust mite allergens may be critical for primary sensitization. Reducing exposure may offer a realistic chance for primary prevention of sensitization and asthma, but it is essential to implement measures that can achieve and maintain the low-allergen environment. Objective: Our purpose was to assess the effectiveness of mite allergen avoidance measures in achieving and maintaining a low-allergen environment during pregnancy and in the first year of life. Methods: The Manchester Asthma and Allergy Study is a prospective, prenatally randomized study that follows the development of asthma and atopy in a cohort of infants at high risk (both parents atopic) who are randomly allocated to full mite allergen avoidance or to a normal regimen. Avoidance measures comprise (1) mite-proof covers (mattress, pillow, and quilt) for parental bed, (2) high-filtration vacuum cleaner, (3) vinyl flooring in infant's bedroom, (4) new crib and portable crib mattresses encased in mite-proof material, (5) benzyl benzoate (Acarosan) applied on carpets and soft furniture, (6) bed linens washed in hot water weekly, and (7) washable soft toys. Dust samples from the parental bed, bedroom floor, living room floor, infant's mattress, and nursery floor were collected between the 10th and 14th weeks of pregnancy, immediately after birth, and then at age 6 months and 1 year, and Der p 1 levels were determined by mAb-based ELISA. Results: Recovered Der p 1 from maternal mattress was reduced by 97.25% (95% confidence interval [CI] 95.25%-98.41%) during the second and third trimesters of pregnancy, with the effect persisting for 6 months (98% reduction, 95% CI 97.25%-99.1%) and 12 months (97.6% reduction, 95% CI 95.7%-98.6%) after the birth (active vs control, P < .000001). Total Der p 1 from bedroom floor in the active group was reduced by 53.7% (95% CI 25.7%-71.2%) in samples collected within 4 weeks of the child's birth, with the percentage reduction being 62.8% (95%
Woodcock H, Craven M, Hadley E, et al., 2000, Aerodynamics of allergens in disturbed conditions, Publisher: MOSBY-YEAR BOOK INC, Pages: S373-S374, ISSN: 0091-6749
Woodcock A, Hallam CL, Woodcock H, et al., 2000, Not only dust mite, but also cat and dog allergen are higher in synthetic than in feather pillows, Publisher: MOSBY-YEAR BOOK INC, Pages: S286-S286, ISSN: 0091-6749
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- Citations: 1
Gore RB, Smith A, Smillie F, et al., 2000, Proliferative T cell responses to the recombinant house dust mite allergen rDer p 2 (D1S), the variant C21/73S, and natural nDer p 2, Publisher: MOSBY-YEAR BOOK INC, Pages: S78-S78, ISSN: 0091-6749
Smillie FI, Patel FY, Tavernier G, et al., 2000, Environmental and genetic effects upon lymphoproliferative responses in 1 year old infants, Publisher: MOSBY-YEAR BOOK INC, Pages: S155-S155, ISSN: 0091-6749
Custovic A, Simpson BM, Simpson A, et al., 2000, Manchester asthma and allergy study (MAAS): Very low allergen environment during pregnancy and in first year of life, Publisher: MOSBY-YEAR BOOK INC, Pages: S271-S271, ISSN: 0091-6749
Simpson BM, Hallam CL, Marolia H, et al., 2000, Manchester asthma and allergy study (MAAS): Recruitment of infant cohort, Publisher: MOSBY-YEAR BOOK INC, Pages: S4-S4, ISSN: 0091-6749
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- Citations: 1
Woodcock A, Custovic A, 2000, Allergen avoidance: does it work?, BRITISH MEDICAL BULLETIN, Vol: 56, Pages: 1071-1086, ISSN: 0007-1420
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- Citations: 11
Woodcock H, Craven M, Hassall R, et al., 1999, Dust mite allergens are not carried only on large particles, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: A26-A26, ISSN: 0040-6376
Custovic A, Woodcock A, 1999, Indoor environment and asthma., Monaldi Arch Chest Dis, Vol: 54, Pages: 465-469, ISSN: 1122-0643
Hallam C, Woodcock H, Craven M, et al., 1999, Synthetic pillows contain higher levels of cat and dog allergen than feather pillows, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: A28-A28, ISSN: 0040-6376
Custovic A, Woodcock H, Craven M, et al., 1999, Dust mite allergens are carried on not only large particles, PEDIATRIC ALLERGY AND IMMUNOLOGY, Vol: 10, Pages: 258-260, ISSN: 0905-6157
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- Citations: 41
Simpson A, Custovic A, Pipis S, et al., 1999, Exhaled nitric oxide, sensitization, and exposure to allergens in patients with asthma who are not taking inhaled steroids, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 160, Pages: 45-49, ISSN: 1073-449X
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- Citations: 71
Costagliola D, Heard I, 1999, Response to: Early regression of cervical lesions in HIV-seropositive women receiving highly active antiretroviral therapy - Reply, AIDS, Vol: 13, Pages: 1150-1150, ISSN: 0269-9370
Custovic A, Simpson B, Simpson A, et al., 1999, Relationship between mite, cat, and dog allergens in reservoir dust and ambient air, ALLERGY, Vol: 54, Pages: 612-616, ISSN: 0105-4538
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- Citations: 80
Green R, Simpson A, Custovic A, et al., 1999, The effect of air filtration on airborne dog allergen, ALLERGY, Vol: 54, Pages: 484-488, ISSN: 0105-4538
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- Citations: 56
Niven RM, Fletcher AM, Pickering AC, et al., 1999, Attempting to control mite allergens with mechanical ventilation and dehumidification in British houses, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 103, Pages: 756-762, ISSN: 0091-6749
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- Citations: 33
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