Imperial College London
Portrait Picture

ProfessorAdnanCustovic

Faculty of Medicine, National Heart & Lung Institute

Professor of Paediatric Allergy
 
 
 
//

Contact

 

a.custovic CV

 
 
//

Location

 

220Medical SchoolSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Akar-Ghibril:2020:10.1016/j.jaip.2019.11.008,
author = {Akar-Ghibril, N and Casale, T and Custovic, A and Phipatanakul, W},
doi = {10.1016/j.jaip.2019.11.008},
journal = {Journal of Allergy and Clinical Immunology: In Practice},
pages = {429--440},
title = {Allergic endotypes and phenotypes of asthma},
url = {http://dx.doi.org/10.1016/j.jaip.2019.11.008},
volume = {8},
year = {2020}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Allergic asthma is defined as asthma associated with sensitization to aeroallergens, which leads to asthma symptoms and airway inflammation. Allergic asthma is the most common asthma phenotype. The onset of allergic asthma is most often in childhood and is usually accompanied by other comorbidities including atopic dermatitis and allergic rhinitis. It is often persistent although there is a wide variation in disease severity. It is a TH2-driven process. Biomarkers have been identified to distinguish patients with allergic asthma, particularly serum IgE levels, tests to indicate sensitization to aeroallergens such as specific IgE or skin prick test positivity, blood and sputum eosinophil levels, fraction of exhaled nitric oxide, and periostin. Treatments for allergic asthma include environmental control measures, allergen immunotherapy, and glucocorticoids. Biologics, targeting the TH2 pathway, have been shown to be effective in the treatment of allergic asthma.
AU  - Akar-Ghibril,N
AU  - Casale,T
AU  - Custovic,A
AU  - Phipatanakul,W
DO  - 10.1016/j.jaip.2019.11.008
EP  - 440
PY  - 2020///
SN  - 2213-2198
SP  - 429
TI  - Allergic endotypes and phenotypes of asthma
T2  - Journal of Allergy and Clinical Immunology: In Practice
UR  - http://dx.doi.org/10.1016/j.jaip.2019.11.008
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000512964500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.sciencedirect.com/science/article/pii/S221321981930947X?via%3Dihub
UR  - http://hdl.handle.net/10044/1/81301
VL  - 8
ER  -
Download