DrAbbasDehghan

Faculty of Medicine, School of Public Health

Reader in Cardiometabolic Disease Epidemiology

Contact

+44 (0)20 7594 3347a.dehghan CV

Location

157Norfolk PlaceSt Mary's Campus

Summary

Abbas Dehghan MD PhD FESC is a medical doctor and an epidemiologist. His main research interest is molecular determinants of complex disorders; mainly cardiovascular diseases and type 2 diabetes. He is a member of the steering committee of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and has led or been involved in many genome-wide association (GWAS) studies in cardiovascular diseases and its risk factors. He has been collaborating with Professor Paul Elliott on a FP7 project, COMBI-BIO, to investigate metabolomics signatures of coronary artery calcification and he has joined the department of epidemiology and biostatistics at Imperial College London since September 2016 as a reader in cardiometabolic disorders. He is aiming to continue working in this field and his ambition is to integrate different omics namely genomics, epigenomics and metabolomics to unravel pathways involved in complex disorders.

Publications

Journals

Gill D, Benyamin B, Moore LSP, et al.Gill D, Benyamin B, Moore LSP, Monori G, Zhou A, Fotios K, Evangelou E, Laffan M, Walker AP, Tsilidis KK, Dehghan A, Elliott P, Hyppönen E, Tzoulaki I close, Associations of genetically determined iron status across the phenome: A Mendelian randomization study, Plos Medicine, ISSN:1549-1277

Open Access Link

Liu J, Carnero-Montoro E, van Dongen J, et al.Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai P-C, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, Willemsen G, de Geus EJC, Chu AY, Levy D, Hwang S-J, Bressler J, Gondalia R, Salfati EL, Herder C, Hidalgo BA, Tanaka T, Moore AZ, Lemaitre RN, Jhun MA, Smith JA, Sotoodehnia N, Bandinelli S, Ferrucci L, Arnett DK, Grallert H, Assimes TL, Hou L, Baccarelli A, Whitsel EA, van Dijk KW, Amin N, Uitterlinden AG, Sijbrands EJG, Franco OH, Dehghan A, Spector TD, Dupuis J, Hivert M-F, Rotter J, Meigs JB, Pankow JS, van Meurs JBJ, Isaacs A, Boomsma D, Bell JT, Demirkan A, van Duijn CM close, 2019, An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis, Nature Communications, Vol:10, ISSN:2041-1723

Ward-Caviness CK, de Vries PS, Wiggins KL, et al.Ward-Caviness CK, de Vries PS, Wiggins KL, Huffman JE, Yanek LR, Bielak LF, Giulianini F, Guo X, Kleber ME, Kacprowski T, Gross S, Petersman A, Smith GD, Hartwig FP, Bowden J, Hemani G, Mueller-Nuraysid M, Strauch K, Koenig W, Waldenberger M, Meitinger T, Pankratz N, Boerwinkle E, Tang W, Fu Y-P, Johnson AD, Song C, de Maat MPM, Uitterlinden AG, Franco OH, Brody JA, McKnight B, Chen Y-DI, Psaty BM, Mathias RA, Becker DM, Peyser PA, Smith JA, Bielinski SJ, Ridker PM, Taylor KD, Yao J, Tracy R, Delgado G, Trompet S, Sattar N, Jukema JW, Becker LC, Kardia SLR, Rotter J, Maerz W, Doerr M, Chasman D, Dehghan A, O'Donnell CJ, Smith NL, Peters A, Morrison AC close, 2019, Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease, Plos One, Vol:14, ISSN:1932-6203

Portilla-Fernandez E, Ghanbari M, van Meurs JBJ, et al.Portilla-Fernandez E, Ghanbari M, van Meurs JBJ, Danser AHJ, Franco OH, Muka T, Roks A, Dehghan A close, 2019, Dissecting the association of autophagy-related genes with cardiovascular diseases and intermediate vascular traits: A population-based approach, Plos One, Vol:14, ISSN:1932-6203

Inker LA, Grams ME, Levey AS, et al.Inker LA, Grams ME, Levey AS, Coresh J, Cirillo M, Collins JF, Gansevoort RT, Gutierrez OM, Hamano T, Heine GH, Ishikawa S, Jee SH, Kronenberg F, Landray MJ, Miura K, Nadkarni GN, Peralta CA, Rothenbacher D, Schaeffner E, Sedaghat S, Shlipak MG, Zhang L, van Zuilen AD, Hallan SI, Kovesdy CP, Woodward M, Levin A, CKD Prognosis Consortium close, 2019, Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium., Am J Kidney Dis, Vol:73, Pages:206-217

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