Imperial College London

DrArmandoDel Rio Hernandez

Faculty of EngineeringDepartment of Bioengineering

Reader in Cellular and Molecular Mechanotransduction
 
 
 
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Contact

 

+44 (0)20 7594 5187a.del-rio-hernandez

 
 
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Location

 

308Bessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Majkowska:2020:10.3389/fmats.2020.00167,
author = {Majkowska, A and Redondo-Gomez, C and Rice, A and Gonzalez, M and Inostroza-Brito, KE and Collin, EC and Rodriguez-Cabello, JC and Hernandez, AEDR and Solito, E and Mata, A},
doi = {10.3389/fmats.2020.00167},
journal = {Frontiers in Materials},
pages = {1--13},
title = {Interfacial self-assembly to spatially organize graphene oxide into hierarchical and bioactive structures},
url = {http://dx.doi.org/10.3389/fmats.2020.00167},
volume = {7},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Multicomponent self-assembly holds great promise for the generation of complex and functional biomaterials with hierarchical microstructure. Here, we describe the use of supramolecular co-assembly between an elastin-like recombinamer (ELR5) and a peptide amphiphile (PA) to organize graphene oxide (GO) flakes into bioactive structures across multiple scales. The process takes advantage of a reaction—diffusion mechanism to enable the incorporation and spatial organization of GO within multiple ELR5/PA layers. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ImageJ software were used to demonstrate the hierarchical organization of GO flakes within the ELR5/PA layers and the distribution profiles of GO throughout the ELR5/PA membranes. Furthermore, atomic force microscopy (AFM) revealed improved Young's Moduli of the ELR5/PA/GO membranes compared to the ELR5/PA membranes. Lastly, we investigated biocompatibility of the ELR5/PA/GO membrane via various cell culture methods.
AU - Majkowska,A
AU - Redondo-Gomez,C
AU - Rice,A
AU - Gonzalez,M
AU - Inostroza-Brito,KE
AU - Collin,EC
AU - Rodriguez-Cabello,JC
AU - Hernandez,AEDR
AU - Solito,E
AU - Mata,A
DO - 10.3389/fmats.2020.00167
EP - 13
PY - 2020///
SN - 2296-8016
SP - 1
TI - Interfacial self-assembly to spatially organize graphene oxide into hierarchical and bioactive structures
T2 - Frontiers in Materials
UR - http://dx.doi.org/10.3389/fmats.2020.00167
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000546892600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - https://www.frontiersin.org/articles/10.3389/fmats.2020.00167/full
UR - http://hdl.handle.net/10044/1/94154
VL - 7
ER -