Force is ubiquitous in nature at all levels of organization. At the cellular scale, physical stimuli integrate with biochemical signals to orchestrate the precisely controlled pathways of proteins interaction that govern the fate of cells. A failure or modification of this subtle control mark the onset of numerous human disorders, particularly those that are highly sensitive to mechanical cues such as cardiovascular diseases and cancer.
Our research is focused on elucidating the mechanisms through which mechanical forces entwine with chemical signaling to regulate the behavior of cells and molecules in physiological conditions; and how these mechanisms are lost or altered in pathological scenarios. To this end, we use a combination of microscopy, nanotechnology, biochemical engineering, and cellular and molecular biology approaches.
For more information, please visit our research website
Dr. Simon Attwood - Research Associate
Dr. Benjamin Robinson - Research Associate
Dr. Muge Sarper - Research Associate
Mr. J. Ernesto Cortes Lopez - Research Assistant
Mr. Anthony Chronopoulos - PhD student
Mr. Mario Polo - MRes student
Mr. Alexander Haining - PhD student
Mrs. Irene Alonso - Visiting postgraduate student