Imperial College London
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ProfessorAndreaCrisanti

Faculty of Natural Sciences, Department of Life Sciences

Professor of Molecular Parasitology
 
 
 
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Contact

 

+44 (0)20 7594 5395a.drcrisanti

 
 
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Assistant

 

Mrs Lucy Collyns +44 (0)20 7594 5395

 
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Location

 

549Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Burt:2018:10.1080/23299460.2017.1419410,
author = {Burt, A and Coulibaly, M and Crisanti, A and Diabate, A and Kayondo, JK},
doi = {10.1080/23299460.2017.1419410},
journal = {Journal of Responsible Innovation},
pages = {S66--S80},
title = {Gene drive to reduce malaria transmission in sub-Saharan Africa},
url = {http://dx.doi.org/10.1080/23299460.2017.1419410},
volume = {5},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Despite impressive progress, malaria continues to impose a substantial burden of mortality and morbidity, particularly in sub-Saharan Africa, and new tools will be needed to achieve elimination. Gene drive is a natural process by which some genes are inherited at a greater-than-Mendelian rate and can spread through a population even if they cause harm to the organisms carrying them. Many different synthetic gene drive systems have been proposed to suppress the number of mosquitoes and/or reduce vector competence. As with any control measure, due attention should be paid to the possible evolution of resistance. No gene drive construct has yet been reported that is ‘field-ready’ for release, and when such constructs are developed, they should be assessed on a case-by-case basis. Gene drive approaches to vector control promise to have a number of key features that motivate their continued development, and scrutiny, by all concerned.
AU  - Burt,A
AU  - Coulibaly,M
AU  - Crisanti,A
AU  - Diabate,A
AU  - Kayondo,JK
DO  - 10.1080/23299460.2017.1419410
EP  - 80
PY  - 2018///
SN  - 2329-9460
SP  - 66
TI  - Gene drive to reduce malaria transmission in sub-Saharan Africa
T2  - Journal of Responsible Innovation
UR  - http://dx.doi.org/10.1080/23299460.2017.1419410
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000434459000005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/61077
VL  - 5
ER  -
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