Imperial College London
Portrait Picture

Professor Alan Fenwick OBE

Faculty of Medicine, School of Public Health

Emeritus Professor
 
 
 
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Contact

 

+44 (0)20 7594 3418a.fenwick Website

 
 
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Location

 

G30Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Assoum:2017:10.1186/s13071-017-2505-x,
author = {Assoum, M and Ortu, G and Basanez, M-G and Lau, C and Clements, ACA and Halton, K and Fenwick, A and Magalhaes, RJS},
doi = {10.1186/s13071-017-2505-x},
journal = {Parasites & Vectors},
title = {Spatiotemporal distribution and population at risk of soil-transmitted helminth infections following an eight-year school-based deworming programme in Burundi, 2007-2014},
url = {http://dx.doi.org/10.1186/s13071-017-2505-x},
volume = {10},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: Investigating the effect of successive annual deworming rounds on the spatiotemporal distribution ofinfection prevalence and numbers at risk for soil-transmitted helminths (STHs) can help identify communitiesnearing elimination and those needing further interventions. In this study, we aim to quantify the impact ofan 8-year mass drug administration (MDA) programme (from 2007 to 2014) on the spatiotemporal distribution ofprevalence of STH infections and to estimate the number of school-aged children infected with STHs in Burundi.Methods: During annual longitudinal school-based surveys in Burundi between 2007 and 2011, STH infection andanthropometric data for a total of 40,656 children were collected; these data were supplemented with data froma national survey conducted in 2014. Bayesian model based geostatistics (MBG) were used to generate predictiveprevalence maps for each STH species and year. The numbers of children at-risk of infection per district between2008 and 2014 were estimated as the product of the predictive prevalence maps and population density maps.Results: Overall, the degree of spatial clustering of STH infections decreased between 2008 and 2011; in 2014 thegeographical clusters of all STH infections reappeared. The reduction in prevalence was small for Ascaris lumbricoidesand Trichuris trichiura in the centre and central north of the country. Our predictive prevalence maps for hookwormindicate a reduction in prevalence along the periphery of the country. The predicted number of children infected withany STH species decreased substantially between 2007 and 2011, but in 2014 there was an increase in the predictednumber of children infected with A. lumbricoides and T. trichiura. In 2014, the districts with the highest predictednumber of children infected with A. lumbricoides, T. trichiura and hookworms were Kibuye district (n = 128,903),Mabayi district (n = 35,302) and Kiremba (n = 87,511), respectively.Conclusions: While the MDA programme
AU  - Assoum,M
AU  - Ortu,G
AU  - Basanez,M-G
AU  - Lau,C
AU  - Clements,ACA
AU  - Halton,K
AU  - Fenwick,A
AU  - Magalhaes,RJS
DO  - 10.1186/s13071-017-2505-x
PY  - 2017///
SN  - 1756-3305
TI  - Spatiotemporal distribution and population at risk of soil-transmitted helminth infections following an eight-year school-based deworming programme in Burundi, 2007-2014
T2  - Parasites & Vectors
UR  - http://dx.doi.org/10.1186/s13071-017-2505-x
UR  - http://hdl.handle.net/10044/1/55927
VL  - 10
ER  -
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