Imperial College London

DrAdamFrampton

Faculty of MedicineDepartment of Surgery & Cancer

Honorary Clinical Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 2125a.frampton

 
 
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Location

 

4005Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Farkas:2020:10.1016/j.amsu.2020.08.028,
author = {Farkas, N and Wong, J and Bethel, J and Monib, S and Frampton, A and Thomson, S},
doi = {10.1016/j.amsu.2020.08.028},
journal = {Annals of Medicine and Surgery},
pages = {52--67},
title = {A systematic review of symptomatic small bowel lipomas of the jejunum and ileum},
url = {http://dx.doi.org/10.1016/j.amsu.2020.08.028},
volume = {58},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - IntroductionSmall bowel lipomas are rarely encountered benign adipose growths found within the small intestine wall or mesentery. Limited up-to-date evidence exists regarding such lipomas. We aim to aid clinical decision-making and improve patient outcomes through this comprehensive review.MethodologyThe terms ‘small bowel,’ ‘small intestine,’ ‘jejunum’ and ‘ileum’ were combined with ‘lipoma.’ EMBASE, Medline and PubMed database searches were performed. All papers published in English from 01/01/2000-31/12/2019 were included. Simple statistical analysis (t-test, Anova) was performed.Results142 papers yielded 147 cases (adults = 138, pediatric = 9). Male = 88, female = 59 (average age = 49.9 years). Presenting symptoms: abdominal pain = 68.7%; nausea/vomiting = 35.3%, hematochezia/GI bleeding = 33.3%; anaemia = 10.9%; abdominal distension = 12.2%; constipation = 8.9%; weight loss = 7.5%. Mean preceding symptom length = 58.1 days (symptoms >1 year excluded (n = 9)). Diagnostic imaging utilised: abdominal X-Ray = 33.3%; endoscopy = 46.3%; CT = 78.2%; ultrasound = 23.8%. 124/137 (90.5%) required definitive surgical management (laparotomy = 89, laparoscopcic = 35). 9 patients were successfully managed endoscopically. Lipoma location: ileum = 59.9%, jejunum = 32%, mesentery = 4.8%. Maximal recorded lipoma size ranged 1.2–22 cm.Mean maximum lipoma diameter and management strategy comparison: laparotomy 5.6 cm, laparoscopic = 4.4 cm, endoscopic = 3.7 cm, conservative = 4.5 cm. One-way Anova test, p value = 0.21. Average length of stay (LOS) was 7.4 days (range = 2–30). T-test p value = 0.13 when comparing management modalities and LOS. 4 complications, 0 mortality.ConclusionsImportant previously undocumented points are illustrated; a clearer symptom profile, diagnostic investigations utilised, size and site of lipomas, types and effectiveness of management modalities, associated morbidity and mortali
AU - Farkas,N
AU - Wong,J
AU - Bethel,J
AU - Monib,S
AU - Frampton,A
AU - Thomson,S
DO - 10.1016/j.amsu.2020.08.028
EP - 67
PY - 2020///
SN - 2049-0801
SP - 52
TI - A systematic review of symptomatic small bowel lipomas of the jejunum and ileum
T2 - Annals of Medicine and Surgery
UR - http://dx.doi.org/10.1016/j.amsu.2020.08.028
UR - https://www.sciencedirect.com/science/article/pii/S2049080120302740?via%3Dihub
UR - http://hdl.handle.net/10044/1/82723
VL - 58
ER -