Publications
448 results found
Frilling A, 2010, Management of neuroendocrine liver metastases according to the type of manifestation, 18th International Symposium on Regulatory Peptides, Publisher: ELSEVIER SCIENCE BV, Pages: 8-8, ISSN: 0167-0115
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- Citations: 1
Frilling A, Sotiropoulos GC, Li J, et al., 2010, Multimodal management of neuroendocrine liver metastases, HPB, Vol: 12, Pages: 361-379, ISSN: 1365-182X
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- Citations: 115
Simon F, Bockhorn M, Praha C, et al., 2010, Deregulation of HIF1-alpha and hypoxia-regulated pathways in hepatocellular carcinoma and corresponding non-malignant liver tissue-influence of a modulated host stroma on the prognosis of HCC, LANGENBECKS ARCHIVES OF SURGERY, Vol: 395, Pages: 395-405, ISSN: 1435-2443
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- Citations: 37
Adam R, Frilling A, Elias D, et al., 2010, Liver resection of colorectal metastases in elderly patients, BRITISH JOURNAL OF SURGERY, Vol: 97, Pages: 366-376, ISSN: 0007-1323
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- Citations: 169
Folprecht G, Gruenberger T, Bechstein WO, et al., 2010, Neoadjuvant Therapy for colorectal Liver metastases with Cetuximab and FOLFOX or Cetuximab and FOLFIRI - Address and Resection., ONKOLOGIE, Vol: 33, Pages: 62-62, ISSN: 0378-584X
Li J, Frilling A, Nadalin S, et al., 2010, Surgical Management of Segmental and Sectoral Bile Duct Injury After Laparoscopic Cholecystectomy: a Challenging Situation, JOURNAL OF GASTROINTESTINAL SURGERY, Vol: 14, Pages: 344-351, ISSN: 1091-255X
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- Citations: 19
Folprecht G, Gruenberger T, Bechstein WO, et al., 2010, Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial, LANCET ONCOLOGY, Vol: 11, Pages: 38-47, ISSN: 1470-2045
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- Citations: 739
Frilling A, Sotiropoulos GC, Kornasiewicz O, et al., 2010, Surgical Treatment of Neuroendocrine Liver Metastases - Resection, Transplantation, VISZERALMEDIZIN, Vol: 26, Pages: 253-261, ISSN: 1662-6664
Wiedenmann B, Frilling A, 2010, Neuroendocrine Tumors of the Gastrointestinal Tract, VISZERALMEDIZIN, Vol: 26, Pages: 224-224, ISSN: 1662-6664
Hou Y-Y, Grabellus F, Weber F, et al., 2009, Impact of KIT and PDGFRA Gene Mutations on Prognosis of Patients with Gastrointestinal Stromal Tumors After Complete Primary Tumor Resection, JOURNAL OF GASTROINTESTINAL SURGERY, Vol: 13, Pages: 1583-1592, ISSN: 1091-255X
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- Citations: 26
Rickenbacher A, Breitenstein S, Lesurtel M, et al., 2009, Efficacy of TachoSil a fibrin-based haemostat in different fields of surgery- a systematic review, EXPERT OPINION ON BIOLOGICAL THERAPY, Vol: 9, Pages: 897-907, ISSN: 1471-2598
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- Citations: 78
Frilling A, 2009, Authors' reply: Treatment of liver metastases from neuroendocrine tumors in relation to the extent of hepatic disease (<i>Br J Surg</i> 2009; 96: 175-184), BRITISH JOURNAL OF SURGERY, Vol: 96, Pages: 823-824, ISSN: 0007-1323
Bockhorn M, Sotiropoulos G, Neuhaus J, et al., 2009, Prognostic impact of intrahepatic lymphatic and microvascular involvement in cases of colorectal liver metastases, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, Vol: 24, Pages: 845-850, ISSN: 0179-1958
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- Citations: 11
Bechstein WO, Lang H, Köhne C, et al., 2009, Resectability and agreement between surgeons: Review of CT and MR scan of the CELIM study: (Multicenter randomized trial of cetuximab/FOLFOX versus cetuximab/FOLFIRI in unresectable liver metastases., J Clin Oncol, Vol: 27
4091 Background: Liver resection of patients with colorectal cancer liver metastasis (mets) may provide curative therapy. The decision for resection is based on CT- or MRI scans and includes technical aspects (esp. remaining liver tissue) and prognostic factors (i.e. number of metastases). METHODS: During two workshops, CT- or MRI scans at baseline (BL) and after 4 months treatment (follow-up, F-U) of CELIM-patients (pts) were presented to surgeons (surg.) who were blinded to each other, the time of investigation (BL or F-U) and clinical data. Scans were allocated to one of the following categories: (1) resection, (2) exploration, (3) borderline resectable (prior chemotherapy preferred) or (4) non-resectable If scans were allocated to category (3) or (4), the reason (technical or poor prognosis) was stated. For evaluation of resectability over time, pts were regarded as resectable according to presented imaging, if ≥ 50% of surg. voted for (1) or (2). Inter-observer variability was evaluated by a reduced model, too: operation (1+2), borderline, primary chemo therapy preferred (3) and non-resectable, chemotherapy (4). Critical disagreements were assumed if ≥1 surg. voted for (4) and ≥ 50% surg. for (1+2) or vice versa. RESULTS: Seven surg. (≥ 5/workshop) participated at the review. A total of 180 scans were reviewed. Both, BL and F-U scans, were available for 75 pts (68% of study pts). During the review, 24 pts changed from 'non-resectable' at BL to 'resectable' at F-U, 5 pts from 'resectable' to 'non-resectable', 29 pts remained 'non-resectable', and 17 pts 'resectable' (19 pts more resectable at F-U; chi-square: p=.021). R0 resection was actually performed in 16/29 pts classified as 'resectable' (55%) and 13/54 pts not classified as 'resectable' (24%) according to presented BL- images. In the full model (6 possibilities), the agreement between surg. was 51.4 %, p<.001. In the clinically more important reduced model, the agreement was 63.5% (p<.001
Bechstein WO, Lang H, Koehne C, et al., 2009, Resectability and agreement between surgeons: Review of CT and MR scan of the CELIM study: (Multicenter randomized trial of cetuximab/FOLFOX versus cetuximab/FOLFIRI in unresectable liver metastases, 45th Annual Meeting of the American-Society-of-Clinical-Oncology, Publisher: AMER SOC CLINICAL ONCOLOGY, ISSN: 0732-183X
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- Citations: 3
Frilling A, Hou Y, Grabellus F, et al., 2009, Impact of KIT and PDGFRA Gene Mutations On Prognosis of Patients with Gastrointestinal Stromal Tumors After Complete Primary Tumor Resection, Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: A885-A885, ISSN: 0016-5085
Frilling A, Li J, Malamutmann E, et al., 2009, Treatment of liver metastases from neuroendocrine tumours in relation to the extent of hepatic disease, BRITISH JOURNAL OF SURGERY, Vol: 96, Pages: 175-184, ISSN: 0007-1323
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- Citations: 168
Bockhorn M, Sotiropoulos GC, Sgourakis G, et al., 2009, Major liver resections in the elderly-is an aggressive approach justified?, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, Vol: 24, Pages: 83-86, ISSN: 0179-1958
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- Citations: 18
Koehne C, Gruenberger T, Bechstein W, et al., 2009, RESULTS FROM THE CELIM STUDY: CETUXIMAB PLUS FOLFOX6 OR CETUXIMAB PLUS FOLFIRI AS NEOADJUVANT TREATMENT FOR NONRESECTABLE COLORECTAL CANCER LIVER METASTASES, 11th World Congress on Gastrointestinal Cancer, Publisher: OXFORD UNIV PRESS, Pages: 23-23, ISSN: 0923-7534
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- Citations: 2
Duh Q-Y, Frilling A, Prinz RA, et al., 2008, Posterior Retroperitoneoscopic Adrenalectomy Preferred Technique for Removal of Benign Tumors and Isolated Metastases Discussions, ANNALS OF SURGERY, Vol: 248, Pages: 672-674, ISSN: 0003-4932
Bockhorn M, Frilling A, Fruehauf NR, et al., 2008, Survival of patients with synchronous and metachronous colorectal liver metastases -: is there a difference?, JOURNAL OF GASTROINTESTINAL SURGERY, Vol: 12, Pages: 1399-1405, ISSN: 1091-255X
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- Citations: 40
Kuehl H, Antoch G, Stergar H, et al., 2008, Comparison of FDG-PET, PET/CT and MRI for follow-up of colorectal liver metastases treated with radiofrequency ablation: Initial results, EUROPEAN JOURNAL OF RADIOLOGY, Vol: 67, Pages: 362-371, ISSN: 0720-048X
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- Citations: 60
Bechmann LP, Hilgard P, Frilling A, et al., 2008, Successful photodynamic therapy for biliary papillomatosis: A case report, WORLD JOURNAL OF GASTROENTEROLOGY, Vol: 14, Pages: 4234-4237, ISSN: 1007-9327
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- Citations: 9
Lencioni R, Crocetti L, Cioni R, et al., 2008, Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study), LANCET ONCOLOGY, Vol: 9, Pages: 621-628, ISSN: 1470-2045
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- Citations: 400
Malago M, Frilling A, Li J, et al., 2008, Cholangiocellular carcinoma - the role of caudate lobe resection and mesohepatectomy, HPB, Vol: 10, Pages: 179-182, ISSN: 1365-182X
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- Citations: 8
Heuer M, Benko T, Cicinnati VR, et al., 2008, Effect of low dose rapamycin on tumor growth in two human hepatocellular cancer cell lines, 8th American Transplant Congress, Publisher: BLACKWELL PUBLISHING, Pages: 423-423, ISSN: 1600-6135
Freudenberg LS, Antoch G, Frilling A, et al., 2008, Combined metabolic and morphologic imaging in thyroid carcinoma patients with elevated serum thyroglobulin and negative cervical ultrasonography:: role of <SUP>124</SUP>I-PET/CT and FDG-PET, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Vol: 35, Pages: 950-957, ISSN: 1619-7070
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- Citations: 44
Cicinnati VR, Kang J, Sotiropoulos GC, et al., 2008, Altered chemotactic response of myeloid and plasmacytoid dendritic cells from patients with chronic hepatitis C: role of alpha interferon, JOURNAL OF GENERAL VIROLOGY, Vol: 89, Pages: 1243-1253, ISSN: 0022-1317
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- Citations: 23
Hass HG, Nehls O, Jobst J, et al., 2008, Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis, WORLD JOURNAL OF GASTROENTEROLOGY, Vol: 14, Pages: 2501-2510, ISSN: 1007-9327
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- Citations: 29
Li J, Frilling A, Nadalin S, et al., 2008, Management of concomitant hepatic artery injury in patients with latrogenic major bile duct injury after laparoscopic cholecystectomy, BRITISH JOURNAL OF SURGERY, Vol: 95, Pages: 460-465, ISSN: 0007-1323
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- Citations: 53
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