Publications
231 results found
Watson MP, George AJT, Larkin DFP, 2006, Differential effects of costimulatory pathway modulation on corneal allograft survival, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol: 47, Pages: 3417-3422, ISSN: 0146-0404
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- Citations: 44
Tan PH, Tan PL, George AJT, et al., 2006, Gene therapy for transplantation with viral vectors - how much of the promise has been realised?, EXPERT OPINION ON BIOLOGICAL THERAPY, Vol: 6, Pages: 759-772, ISSN: 1471-2598
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- Citations: 11
Soleimani B, Lechler RI, Hornick PI, et al., 2006, Role of alloantibodies in the pathogenesis of graft arteriosclerosis in cardiac transplantation, AMERICAN JOURNAL OF TRANSPLANTATION, Vol: 6, Pages: 1781-1785, ISSN: 1600-6135
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- Citations: 34
Tan PH, George AJT, Handa AI, 2006, Gene therapy for clinical transplantation: where do we stand in 2006?, Discov Med, Vol: 6, Pages: 153-156
Gene therapy holds a great promise to prevent allograft rejection or to induce transplant tolerance. Many achievements in vector development have allowed the progression of this therapy to become more attainable in clinical transplantation. In this articles, the authors examine the exciting development in various vector technologies that allows this form of therapy to take the central stage of clinical transplantation. Also highlighted are various therapeutic strategies that might ultimately result in the realization of gene-based treatment in clinical transplantation.
Garden OA, Reynolds PR, Yates J, et al., 2006, A rapid method for labelling CD4<SUP>+</SUP> T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour <i>in vitro</i>, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 314, Pages: 123-133, ISSN: 0022-1759
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- Citations: 32
Manunta M, Nichols BJ, Tan PH, et al., 2006, Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 314, Pages: 134-146, ISSN: 0022-1759
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- Citations: 48
Tan PH, Chan CLH, George AJT, 2006, Strategies to improve non-viral vectors - potential applications in clinical transplantation, EXPERT OPINION ON BIOLOGICAL THERAPY, Vol: 6, Pages: 619-630, ISSN: 1471-2598
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- Citations: 10
Beutelspacher SC, Tan PH, McClure MO, et al., 2006, Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: Implications for the control of alloresponses, AMERICAN JOURNAL OF TRANSPLANTATION, Vol: 6, Pages: 1320-1330, ISSN: 1600-6135
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- Citations: 84
Zhang X-X, George A, Bailey MJ, et al., 2006, The histidine utilization (<i>hut</i>) genes of <i>Pseudomonas fluorescens</i> SBW25 are active on plant surfaces, but are not required for competitive colonization of sugar beet seedlings, MICROBIOLOGY-SGM, Vol: 152, Pages: 1867-1875, ISSN: 1350-0872
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- Citations: 30
Tan PH, George AJT, 2006, Differential Expression of Indoleamine 2,3-dioxygenase (IDO) by Endothelial Cells and Its Overexpression by Gene Transfer: Implications for Cardiovascular Biology, Publisher: NATURE PUBLISHING GROUP, Pages: S337-S338, ISSN: 1525-0016
Kodama T, Tan PH, George AJT, et al., 2006, Delivery of Oligodeoxynucleotides into Human Saphenous Veins and the Adjunct Effect of Ultrasound and Microbubbles, Publisher: NATURE PUBLISHING GROUP, Pages: S212-S212, ISSN: 1525-0016
Tan PH, Beutelspacher SC, George AJT, 2006, Use of Equine Infectious Anaemia Virus (EIAV) To Mediate Indoleamine 2,3-dioxygenase Gene Transfer to Murine Corneal Allograft Transplantation Model Results in Prolongation of Allograft Survival <i>In Vivo</i> with Little Immunogenicity, Publisher: NATURE PUBLISHING GROUP, Pages: S179-S180, ISSN: 1525-0016
Tan PH, Manunta M, George AJT, 2006, Role of Caveoli on Membrane Raft in the Internalization of Non-Viral Vectors, Publisher: NATURE PUBLISHING GROUP, Pages: S151-S151, ISSN: 1525-0016
Tan PH, Lechler RI, Lombardi G, et al., 2006, Genetic Manipulation of Dendritic Cells through the Use of Immunolipoplexes To Induce T Cell-Specific Tolerance <i>In Vivo</i>, Publisher: NATURE PUBLISHING GROUP, Pages: S76-S76, ISSN: 1525-0016
Tan PH, Xue SA, Manunta M, et al., 2006, Effect of vectors on human endothelial cell signal transduction - Implications for cardiovascular gene therapy, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Vol: 26, Pages: 462-467, ISSN: 1079-5642
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- Citations: 27
Beutelspacher SC, Pillai R, Watson MP, et al., 2006, Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 36, Pages: 690-700, ISSN: 0014-2980
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- Citations: 152
Lechler RI, George AJT, 2006, Transplantation and Rejection, Immunology, Editors: Male, Brostoff, Roth, Roitt, Philadelphia, Publisher: Mosby Elsevier, Pages: 383-399, ISBN: 9780323033992
Chan C, Stark J, George AJT, 2005, The impact of multiple T cell-APC encounters and the role of anergy, JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS, Vol: 184, Pages: 101-120, ISSN: 0377-0427
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- Citations: 9
George AJT, Stark J, Chan C, 2005, Understanding specificity and sensitivity of T-cell recognition, TRENDS IN IMMUNOLOGY, Vol: 26, Pages: 653-659, ISSN: 1471-4906
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- Citations: 36
Harper JE, Tan PH, George AJT, 2005, Inhibition of costimulation using intracellular fusion proteins, IMMUNOLOGY, Vol: 116, Pages: 76-76, ISSN: 0019-2805
Kodama T, Tan PH, Offiah I, et al., 2005, Delivery of oligodeoxynucleotides into human saphenous veins and the adjunct effect of ultrasound and microbubbles, ULTRASOUND IN MEDICINE AND BIOLOGY, Vol: 31, Pages: 1683-1691, ISSN: 0301-5629
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- Citations: 28
Tan PH, Chan CLH, Chan C, et al., 2005, The evolving role of gene-based treatment in surgery, BRITISH JOURNAL OF SURGERY, Vol: 92, Pages: 1466-1480, ISSN: 0007-1323
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- Citations: 10
Mirenda V, Millington O, Lechler RI, et al., 2005, Tolerant T cells display impaired trafficking ability, IMMUNOLOGY, Vol: 116, Pages: 44-44, ISSN: 0019-2805
Tan PH, Yates JB, Xue SA, et al., 2005, Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression, BLOOD, Vol: 106, Pages: 2936-2943, ISSN: 0006-4971
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- Citations: 54
Mirenda V, Millington O, Lechler RI, et al., 2005, Tolerant T cells display impaired trafficking ability, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 35, Pages: 2146-2156, ISSN: 0014-2980
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- Citations: 17
Tan PH, Sagoo P, Chan C, et al., 2005, Inhibition of NF-κB and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells, JOURNAL OF IMMUNOLOGY, Vol: 174, Pages: 7633-7644, ISSN: 0022-1767
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- Citations: 176
Beutelspacher SC, Ardjomand N, Tan PH, et al., 2005, Comparison of HIV-1 and EIAV-based lentiviral vectors in corneal transduction, EXPERIMENTAL EYE RESEARCH, Vol: 80, Pages: 787-794, ISSN: 0014-4835
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- Citations: 38
Tan PH, Beutelspacher SC, Xue SA, et al., 2005, Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy, BLOOD, Vol: 105, Pages: 3824-3832, ISSN: 0006-4971
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- Citations: 119
Tan PH, Beutelspacher SC, Wang YH, et al., 2005, Immunolipoplexes: An efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination, MOLECULAR THERAPY, Vol: 11, Pages: 790-800, ISSN: 1525-0016
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- Citations: 46
George AJT, 2005, Dendritic cells in cancer immunotherapy - 10 January 2005, London, UK, IDRUGS, Vol: 8, Pages: 104-106, ISSN: 1369-7056
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