Imperial College London
Alternate

Emeritus ProfessorAndrewGeorge

Faculty of Medicine, Department of Surgery & Cancer

Emeritus Professor
 
 
 
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Contact

 

a.george

 
 
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Location

 

Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

231 results found

Chan CCW, Stark J, George AJT, 1999, Analysis of cytokine dynamics in corneal allograft rejection, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 266, Pages: 2217-2223, ISSN: 0962-8452

Journal article

Callard R, George AJT, Stark J, 1999, Cytokines, chaos, and complexity, IMMUNITY, Vol: 11, Pages: 507-513, ISSN: 1074-7613

Journal article

Hudde T, Rayner SA, Comer RM, Weber M, Isaacs JD, Waldmann H, Larkin DPF, George AJTet al., 1999, Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium, GENE THERAPY, Vol: 6, Pages: 939-943, ISSN: 0969-7128

Journal article

George AJT, Gray D, 1999, Receptor editing during affinity maturation, IMMUNOLOGY TODAY, Vol: 20, Pages: 196-196, ISSN: 0167-5699

Journal article

Arancibia CV, Tai AKF, George AJT, Ono SJ, Streilein JWet al., 1999, Deviant regulation of class II MHC expression in corneal endothelial cells, Publisher: FEDERATION AMER SOC EXP BIOL, Pages: A277-A277, ISSN: 0892-6638

Conference paper

Nicholson S, Gallop JL, Law P, Thomas H, George AJTet al., 1999, Monitoring antibody responses to cancer vaccination with a resonant mirror biosensor, LANCET, Vol: 353, Pages: 808-808, ISSN: 0140-6736

Journal article

Oral HB, Arancibia-Cárcamo CV, Haskard DO, George AJTet al., 1999, A method for determining the cytoprotective effect of catalase in transiently transfected cell lines and in corneal tissue, ANALYTICAL BIOCHEMISTRY, Vol: 267, Pages: 196-202, ISSN: 0003-2697

Journal article

Palmer DB, Crompton T, Marandi MB, George AJT, Ritter MAet al., 1999, Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development, IMMUNOLOGY, Vol: 96, Pages: 236-245, ISSN: 0019-2805

Journal article

Lord GM, Lecler RI, George AJT, 1999, A kinetic differentiation model for the action of altered TCR ligands, IMMUNOLOGY TODAY, Vol: 20, Pages: 33-39, ISSN: 0167-5699

Journal article

Riesbeck K, Chen DX, Kemball-Cook G, McVey JH, George AJT, Tuddenham EGD, Dorling A, Lechler RIet al., 1998, Expression of hirudin fusion proteins in mammalian cells - A strategy for prevention of intravascular thrombosis, CIRCULATION, Vol: 98, Pages: 2744-2752, ISSN: 0009-7322

Journal article

George AJT, 1998, The application of biosensor technology to the detection and characterisation of polyclonal antibody reactivity, International Journal of Bio-Chromatography, Vol: 4, Pages: 187-202, ISSN: 1068-0659

Biosensor technology, both the resonant mirror (IAsys) and the surface plasmon resonance (BIAcore) biosensors have allowed the relatively easy determination of the kinetics and affinity of interaction of homogeneous interactions, such as those between monoclonal antibodies and antigen. However, relatively little attention has been paid to measuring heterogeneous interactions, such as occur between polyclonal antibodies and their antigens. However, these interactions can be clinically important, for example in determining the success of vaccination protocols. This paper reviews some settings where an understanding of the affinity and/or kinetics of polyclonal antibody interactions might be of clinical benefit, some studies in which interactions of serum antibodies have been investigated using biosensors and also at how data from such experiments might be analysed.

Journal article

McKay PF, Imami N, Johns M, Taylor-Fishwick DA, Sedibane LM, Totty NF, Hsuan JJ, Palmer DB, George AJT, Foxwell BMJ, Ritter MAet al., 1998, The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 28, Pages: 4071-4083, ISSN: 0014-2980

Journal article

Heelan BT, Osman S, Blyth A, Schnorr L, Jones T, George AJTet al., 1998, Use of 2-[<SUP>18</SUP>F]fluoro-2-deoxyglucose as a potential agent in the prediction of graft rejection by positron emission tomography, TRANSPLANTATION, Vol: 66, Pages: 1101-1103, ISSN: 0041-1337

Journal article

Lee J, Cairns T, McKane W, Rashid M, George AJT, Taube Det al., 1998, Demonstration of IgM antibodies of high affinity within the anti-Galα1-3Gal antibody repertoire, TRANSPLANTATION, Vol: 66, Pages: 1117-1119, ISSN: 0041-1337

Journal article

Hussain R, Siligardi G, George AJT, Verma Ret al., 1998, Immobilised and non-immobilised ligand interaction studies of monoclonal antibody BC-1 and ED-B containing fibronectin fragment., PROTEIN AND PEPTIDE LETTERS, Vol: 5, Pages: 215-219, ISSN: 0929-8665

Journal article

Verma R, Boleti E, George AJT, 1998, Antibody engineering: Comparison of bacterial, yeast, insect and mammalian expression systems, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 216, Pages: 165-181, ISSN: 0022-1759

Journal article

Nicholson S, George AJT, Thomas H, 1998, Measurement of the idiotypic network response to monoclonal antibody therapy for ovarian cancer, Publisher: PERGAMON-ELSEVIER SCIENCE LTD, Pages: S38-S38, ISSN: 0959-8049

Conference paper

Rayner SA, Gallop JL, George AJT, Larkin DFPet al., 1998, Distribution of integrins α<sub>v</sub>β<sub>5</sub>, α<sub>v</sub>β<sub>3</sub> and α<sub>v</sub> in normal human cornea:: possible implications in clinical and therapeutic adenoviral infection, EYE, Vol: 12, Pages: 273-277, ISSN: 0950-222X

Journal article

Arancibia CV, Hart SL, Oral HB, Larkin DFP, George AJTet al., 1998, Gene transfer to the corneal endothelium: A potential for modulating allograft rejection., Publisher: FEDERATION AMER SOC EXP BIOL, Pages: A310-A310, ISSN: 0892-6638

Conference paper

Mahiouz DL, Aichinger G, Haskard DO, George AJTet al., 1998, Expression of recombinant anti-E-selectin single-chain Fv antibody fragments in stably transfected insect cell lines, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 212, Pages: 149-160, ISSN: 0022-1759

Journal article

Hart SL, Arancibia-Cárcamo CV, Wolfert MA, Mailhos C, O'Reilly NJ, Ali RR, Coutelle C, George AJT, Harbottle RP, Knight AM, Larkin DFP, Levinsky RJ, Seymour LW, Thrasher AJ, Kinnon Cet al., 1998, Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector, HUMAN GENE THERAPY, Vol: 9, Pages: 575-585, ISSN: 1043-0342

Journal article

Patel MJ, Webb EJ, Shelbourn TE, Mattia-Goldberg C, George AJT, Zhang F, Moore EG, Nelson DJet al., 1998, Absence of immunogenicity of diaspirin cross-linked hemoglobin in humans, BLOOD, Vol: 91, Pages: 710-716, ISSN: 0006-4971

Journal article

Arancibia-Cárcamo CV, Oral HB, Haskard DO, Larkin DFP, George AJTet al., 1998, Lipoadenofection-mediated gene delivery to the corneal endothelium:: Prospects for modulating graft rejection, TRANSPLANTATION, Vol: 65, Pages: 62-67, ISSN: 0041-1337

Journal article

Oral HB, George AJT, Haskard DO, 1998, A sensitive fluorometric assay for determining hydrogen peroxide-mediated sublethal and lethal endothelial cell injury, ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH, Vol: 6, Pages: 143-151, ISSN: 1062-3329

Journal article

Harrison AA, Stocker CJ, Chapman PT, Tsang YT, Huehns TY, Gundel RH, Peters AM, Davies KA, George AJ, Robinson MK, Haskard DOet al., 1997, Expression of vascular cell adhesion molecule-1 by vascular endothelial cells in immune and nonimmune inflammatory reactions in the skin, JOURNAL OF IMMUNOLOGY, Vol: 159, Pages: 4546-4554, ISSN: 0022-1767

Journal article

George AJT, Gallop JL, Rashid M, 1997, Kinetics of biomolecular interactions, EXPERT OPINION ON THERAPEUTIC PATENTS, Vol: 7, Pages: 947-963, ISSN: 1354-3776

Journal article

Fehervari Z, Rayner SA, Oral HB, George AJT, Larkin DFPet al., 1997, Gene transfer to ex vivo stored corneas, CORNEA, Vol: 16, Pages: 459-464, ISSN: 0277-3740

Journal article

Oral HB, Larkin DFP, Fehervari Z, Byrnes AP, Rankin AM, Haskard DO, Wood MJA, Dallman MJ, George AJTet al., 1997, Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea, GENE THERAPY, Vol: 4, Pages: 639-647, ISSN: 0969-7128

Journal article

Palmer DB, George AJT, Ritter MA, 1997, Selection of antibodies to cell surface determinants on mouse thymic epithelial cells using a phage display library, IMMUNOLOGY, Vol: 91, Pages: 473-478, ISSN: 0019-2805

Journal article

Turner DJ, Ritter MA, George AJT, 1997, Importance of the linker in expression of single-chain Fv antibody fragments: Optimisation of peptide sequence using phage display technology, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 205, Pages: 43-54, ISSN: 0022-1759

Journal article

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