Summary
Angelika Gründling is a Professor in Molecular Microbiology at Imperial College London, where she started her independent research career in 2007. The research focuses onthe investigation of fundamental processes that are essential for the growth of Gram-positive bacterial pathogens. She combines genetic, biochemical and in collaborations structural approaches to provide mechanistic insight into cell wall synthesis and nucleotide signalling pathways in Staphylococcus aureus and Listeria monocytogenes.Angelika obtained her Ph.D. in Microbiology from the University of Vienna in 2000. She performed her postdoctoral training at the Harvard Medical School, where she investigated flagallar motility in the bacterial pathogen Listeria monocytogenes and at the University of Chicago, where she initiated her studies on the cell wall of S. aureus. At Imperial College London she continues her work on the bacterial cell wall and more recently on the essential signalling nucleotide c-di-AMP.
Publications
Journals
Wu C-H, Rismondo J, Morgan RML, et al., 2021, Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth, Journal of Biological Chemistry, ISSN:0021-9258
Rismondo J, Schulz LM, Yacoub M, et al., 2021, EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes., Journal of Bacteriology, Vol:203, ISSN:0021-9193, Pages:1-16
Rismondo J, Gillis A, Grundling A, 2021, Modifications of cell wall polymers in Gram-positive bacteria by multi-component transmembrane glycosylation systems, Current Opinion in Microbiology, ISSN:1369-5274
Zhang K, Raju C, Zhong W, et al., 2021, Cationic Glycosylated Block Co-β-peptide Acts on the Cell Wall of Gram-Positive Bacteria as Anti-biofilm Agents, Acs Applied Bio Materials
Zhong W, Shi Z, Mahadevegowda SH, et al., 2020, Designer broad-spectrum polyimidazolium antibiotics, Proceedings of the National Academy of Sciences of Usa, Vol:117, ISSN:0027-8424, Pages:31376-31385