Summary
Angelika Gründling is a Professor in Molecular Microbiology at Imperial College London, where she started her independent research career in 2007. The research focuses onthe investigation of fundamental processes that are essential for the growth of Gram-positive bacterial pathogens. She combines genetic, biochemical and in collaborations structural approaches to provide mechanistic insight into cell wall synthesis and nucleotide signalling pathways in Staphylococcus aureus and Listeria monocytogenes.Angelika obtained her Ph.D. in Microbiology from the University of Vienna in 2000. She performed her postdoctoral training at the Harvard Medical School, where she investigated flagallar motility in the bacterial pathogen Listeria monocytogenes and at the University of Chicago, where she initiated her studies on the cell wall of S. aureus. At Imperial College London she continues her work on the bacterial cell wall and more recently on the essential signalling nucleotide c-di-AMP.
Publications
Journals
Beetham CM, Schuster CF, Kviatkovski I, et al., 2024, Histidine transport is essential for the growth of Staphylococcus aureus at low pH, Plos Pathogens, ISSN:1553-7366
Millership C, Gründling A, 2024, Type I Lipoteichoic Acid (LTA) Detection by Western Blot., Methods Mol Biol, Vol:2727, Pages:95-106
Rismondo J, Gründling A, 2024, Type I Lipoteichoic Acid (LTA) Purification by Hydrophobic Interaction Chromatography and Structural Analysis by 2D Nuclear Magnetic Resonance (NMR) Spectroscopy., Methods Mol Biol, Vol:2727, Pages:107-124
Zeden MS, Schuster CF, Gründling A, 2023, Preparation of Electrocompetent Staphylococcus aureus Cells and Plasmid Transformation., Cold Spring Harb Protoc, Vol:2023
Zeden MS, Schuster CF, Gründling A, 2023, Construction of a Staphylococcus aureus Gene-Deletion Allelic-Exchange Plasmid by Gibson Assembly and Recovery in Escherichia coli., Cold Spring Harb Protoc, Vol:2023