Imperial College London
Alternate

Professor Alun H Davies, MA,DM,DSc,FRCS,FHEA,FEBVS,FACPh

Faculty of Medicine, Department of Surgery & Cancer

Professor of Vascular Surgery
 
 
 
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Contact

 

+44 (0)20 3311 7309a.h.davies

 
 
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Location

 

4E04 EastEast WingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Smith:2022:10.3390/life12081185,
author = {Smith, S and Normahani, P and Lane, T and Hohenschurz-Schmidt, D and Oliver, N and Davies, AH},
doi = {10.3390/life12081185},
journal = {Life},
pages = {1185--1185},
title = {Prevention and management strategies for diabetic neuropathy},
url = {http://dx.doi.org/10.3390/life12081185},
volume = {12},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Diabetic neuropathy (DN) is a common complication of diabetes that is becoming an increasing concern as the prevalence of diabetes rapidly rises. There are several types of DN, but the most prevalent and studied type is distal symmetrical polyneuropathy, which is the focus of this review and is simply referred to as DN. It can lead to a wide range of sensorimotor and psychosocial symptoms and is a major risk factor for diabetic foot ulceration and Charcot neuropathic osteoarthropathy, which are associated with high rates of lower limb amputation and mortality. The prevention and management of DN are thus critical, and clinical guidelines recommend several strategies for these based on the best available evidence. This article aims to provide a narrative review of DN prevention and management strategies by discussing these guidelines and the evidence that supports them. First, the epidemiology and diverse clinical manifestations of DN are summarized. Then, prevention strategies such as glycemic control, lifestyle modifications and footcare are discussed, as well as the importance of early diagnosis. Finally, neuropathic pain management strategies and promising novel therapies under investigation such as neuromodulation devices and nutraceuticals are reviewed.
AU  - Smith,S
AU  - Normahani,P
AU  - Lane,T
AU  - Hohenschurz-Schmidt,D
AU  - Oliver,N
AU  - Davies,AH
DO  - 10.3390/life12081185
EP  - 1185
PY  - 2022///
SN  - 2075-1729
SP  - 1185
TI  - Prevention and management strategies for diabetic neuropathy
T2  - Life
UR  - http://dx.doi.org/10.3390/life12081185
UR  - http://mdpi.com/2075-1729/12/8/1185
UR  - http://hdl.handle.net/10044/1/98916
VL  - 12
ER  -
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