Imperial College London
Portrait Picture

ProfessorAylinHanyaloglu

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor in Molecular Medicine
 
 
 
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Contact

 

+44 (0)20 7594 2128a.hanyaloglu Website

 
 
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Assistant

 

Miss Kiran Dosanjh +44 (0)20 7594 2176

 
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Location

 

2009Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Caengprasath:2019:10.1016/j.ceb.2018.12.009,
author = {Caengprasath, N and Hanyaloglu, A},
doi = {10.1016/j.ceb.2018.12.009},
journal = {Current Opinion in Cell Biology},
pages = {77--82},
title = {Hardwiring wire-less networks: spatially encoded GPCR signaling in endocrine systems},
url = {http://dx.doi.org/10.1016/j.ceb.2018.12.009},
volume = {57},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The pivotal and diverse roles G protein-coupled receptors (GPCRs) play in physiology are matched by the increasingly complex signal systems they activate. Over the past decade, our models of GPCR signaling systems also include a vital role of location in controlling GPCR signaling, whereby plasma membrane, clathrin-associated structures and a diverse endomembrane network provide highly specialized signal platforms for this superfamily of receptors. The aim of this review is to highlight the recent developments in this fast-evolving field, with particular emphasis on endocrine-relevant GPCRs. We will also highlight studies that address the possibility of therapeutic intervention and how this fundamental cell biology can be translated to physiology/pathophysiology and therapeutic interventions.
AU  - Caengprasath,N
AU  - Hanyaloglu,A
DO  - 10.1016/j.ceb.2018.12.009
EP  - 82
PY  - 2019///
SN  - 0955-0674
SP  - 77
TI  - Hardwiring wire-less networks: spatially encoded GPCR signaling in endocrine systems
T2  - Current Opinion in Cell Biology
UR  - http://dx.doi.org/10.1016/j.ceb.2018.12.009
UR  - http://hdl.handle.net/10044/1/66807
VL  - 57
ER  -
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