Imperial College London

ProfessorAlunHughes

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

a.hughes Website

 
 
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Assistant

 

Mrs Kim Cyrus +44 (0)20 7594 6047

 
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Location

 

59/61 North Wharf RoadSt Mary's Campus

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Summary

 

Summary

Alun Hughes is currently Professor of Cardiovascular Physiology and Pharmacology, UCL and a visiting professor at Imperial College London. He held a chair in Clinical Pharmacology at Imperial College London from 2001-13. He currently also holds a visiting professorship in the Department of Pharmacology, University of Aarhus, Denmark.

Professor Hughes completed his medical degree (MB, BS) at St Mary's Hospital Medical School in 1983 having obtained a 1st class intercalated BSc degree in Physiology in 1979. He was awarded a PhD from the University of London in 1988 for his work on vascular dopamine receptors. Subsequently  he was a Medical Research Council Training Fellow at  St George's Hospital Medical School, a British Heart Foundation Intermediate Fellow at Imperial College of Science, Technology & Medicine and Senior Lecturer/Reader at Imperial College London.

His work focuses on the structure and function of the cardiovascular system in health and disease. Previous achievements have included the identification of tyrosine phosphorylation as a regulator of calcium channels in vascular smooth muscle,defining the mechanism of the vasodilator action of thiazide diuretics on the vasculature and the application of wave intensity analysis in man. More recently, he has extended his interests into developing novel imaging and computational methods for the assessment of haemodynamics and cardiovascular function in man in vivo and their application to large scale clinical trials and epidemiological studies, such as Southall and Brent Revisited (SABRE),  the Anglo Scandinavian Cardiac Outcomes Trial (ASCOT), the Lifelong Health & Ageing: National Survey of Health and Development and the Avon Longitudinal Study of Parents and Children (ALSPAC).

Professor Hughes was President of the European Council for Cardiovascular Research from 2008-2010, and is currently a faculty member and hononary Professor of the Danish Cardiovascular Research Academy (DaCRA).

Publications

Journals

Mason SA, Al Saikhan L, Jones S, et al., 2022, Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation, Neuroimage, Vol:257, ISSN:1053-8119

Picone DS, Stoneman E, Cremer A, et al., 2022, Sex Differences in Blood Pressure and Potential Implications for Cardiovascular Risk Management., Hypertension

Alfarih M, Augusto JB, Knott KD, et al., 2022, Saturation-pulse prepared heart-rate independent inversion-recovery (SAPPHIRE) biventricular T1 mapping: inter-field strength, head-to-head comparison of diastolic, systolic and dark-blood measurements, Bmc Medical Imaging, Vol:22, ISSN:1471-2342

Jacques Wels, Booth C, Wielgoszewska B, et al., 2022, Mental and social wellbeing and the UK coronavirus job retention scheme: Evidence from nine longitudinal studies, Social Science & Medicine, ISSN:0277-9536, Pages:115226-115226

O'Nunain KM, Park CD, Urquijo H, et al., 2022, A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure, Plos Biology, Vol:20, ISSN:1544-9173

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