Imperial College London

ProfessorAlunHughes

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

a.hughes Website

 
 
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Assistant

 

Mrs Kim Cyrus +44 (0)20 7594 6047

 
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Location

 

59/61 North Wharf RoadSt Mary's Campus

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Summary

 

Summary

Alun Hughes is currently Professor of Cardiovascular Physiology and Pharmacology, UCL and a visiting professor at Imperial College London. He held a chair in Clinical Pharmacology at Imperial College London from 2001-13. He currently also holds a visiting professorship in the Department of Pharmacology, University of Aarhus, Denmark.

Professor Hughes completed his medical degree (MB, BS) at St Mary's Hospital Medical School in 1983 having obtained a 1st class intercalated BSc degree in Physiology in 1979. He was awarded a PhD from the University of London in 1988 for his work on vascular dopamine receptors. Subsequently  he was a Medical Research Council Training Fellow at  St George's Hospital Medical School, a British Heart Foundation Intermediate Fellow at Imperial College of Science, Technology & Medicine and Senior Lecturer/Reader at Imperial College London.

His work focuses on the structure and function of the cardiovascular system in health and disease. Previous achievements have included the identification of tyrosine phosphorylation as a regulator of calcium channels in vascular smooth muscle,defining the mechanism of the vasodilator action of thiazide diuretics on the vasculature and the application of wave intensity analysis in man. More recently, he has extended his interests into developing novel imaging and computational methods for the assessment of haemodynamics and cardiovascular function in man in vivo and their application to large scale clinical trials and epidemiological studies, such as Southall and Brent Revisited (SABRE),  the Anglo Scandinavian Cardiac Outcomes Trial (ASCOT), the Lifelong Health & Ageing: National Survey of Health and Development and the Avon Longitudinal Study of Parents and Children (ALSPAC).

Professor Hughes was President of the European Council for Cardiovascular Research from 2008-2010, and is currently a faculty member and hononary Professor of the Danish Cardiovascular Research Academy (DaCRA).

Publications

Journals

Topriceanu C-C, Wong A, Moon JC, et al., 2021, Impact of lockdown on key workers: findings from the COVID-19 survey in four UK national longitudinal studies., J Epidemiol Community Health, Vol:75, Pages:955-962

Khanolkar AR, Chaturvedi N, Kuan V, et al., 2021, Socioeconomic inequalities in prevalence and development of multimorbidity across adulthood: A longitudinal analysis of the MRC 1946 National Survey of Health and Development in the UK., Plos Med, Vol:18

Min JL, Hemani G, Hannon E, et al., 2021, Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation., Nat Genet, Vol:53, Pages:1311-1321

Torlasco C, D'Silva A, Bhuva AN, et al., 2021, Age matters: differences in exercise-induced cardiovascular remodelling in young and middle aged healthy sedentary individuals., Eur J Prev Cardiol, Vol:28, Pages:738-746

Aizawa K, Casanova F, Gates PE, et al., 2021, Reservoir-Excess Pressure Parameters Independently Predict Cardiovascular Events in Individuals With Type 2 Diabetes., Hypertension, Vol:78, Pages:40-50

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