Imperial College London

ProfessorAlunHughes

Faculty of MedicineNational Heart & Lung Institute

Visiting Professor
 
 
 
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Contact

 

a.hughes Website

 
 
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Assistant

 

Mrs Kim Cyrus +44 (0)20 7594 6047

 
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Location

 

59/61 North Wharf RoadSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

1335 results found

Stanton AV, Mayet J, Hughes AD, Chapman NJ, Sever PS, Thom SAet al., 1996, Carotid and femoral artery intima-media thickness is similar in black and white hypertensive patients., HYPERTENSION, Vol: 28, Pages: 703-703, ISSN: 0194-911X

Journal article

Thom SA, Stanton AV, King LA, Sever PS, Hughes ADet al., 1996, Arteriolar length-diameter ratio; A geometric parameter of the retinal vasculature diagnostic of hypertension., HYPERTENSION, Vol: 28, Pages: 703-703, ISSN: 0194-911X

Journal article

Ibrahim J, Hughes AD, Sever PS, 1996, Non-AT1/AT2 receptor mediated growth by angiotensin II in human saphenous vein in culture, HYPERTENSION, Vol: 28, Pages: 701-701, ISSN: 0194-911X

Journal article

Chapman N, Mohamudally A, Stanton A, Sever P, Sayer AA, Cooper C, Barker D, Wormald R, Evans J, Rauf A, Hughes A, Thom Set al., 1996, Abnormal microvascular network geometry - The link between low birth weight and increased cardiovascular risk?, HYPERTENSION, Vol: 28, Pages: 703-703, ISSN: 0194-911X

Journal article

Xie LD, Clunn GF, Hughes AD, 1996, Intracellular signals involved in the attachment of vascular smooth muscle cells to fibrinogen, HYPERTENSION, Vol: 28, Pages: 687-687, ISSN: 0194-911X

Journal article

Hughes AD, Clunn GF, Refson J, DemoliouMason Cet al., 1996, Platelet-derived growth factor (PDGF): Actions and mechanisms in vascular smooth muscle, GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM, Vol: 27, Pages: 1079-1089, ISSN: 0306-3623

Journal article

Puliyel JM, Hughes A, Chiswick ML, Mughal MZet al., 1996, Adverse local reactions from accidental BCG overdose in infants, BRITISH MEDICAL JOURNAL, Vol: 313, Pages: 528-529, ISSN: 0959-8138

Journal article

Patel MK, Clunn GF, Lymn JS, Hughes ADet al., 1996, Thrombospondin-1 induces DNA synthesis and migration in human vascular smooth muscle cells., 658th Meeting of the Biochemical-Society, Publisher: PORTLAND PRESS, Pages: S446-S446, ISSN: 0300-5127

Conference paper

Patel MK, Clunn GF, Lymn JS, Hughes ADet al., 1996, Thrombospondin-1 induces DNA synthesis and migration in human vascular smooth muscle cells., Biochem Soc Trans, Vol: 24, ISSN: 0300-5127

Journal article

Ibrahim J, Hughes AD, Schachter M, Sever PSet al., 1996, Depletion of resistance vessel polyamines attenuates angiotensin II induced blood pressure rise in rats, CLINICAL AND EXPERIMENTAL HYPERTENSION, Vol: 18, Pages: 811-830, ISSN: 1064-1963

Journal article

Pickkers P, Schachter M, Hughes AD, Feher MD, Sever PSet al., 1996, Thiazide-induced hyperglycaemia: A role for calcium-activated potassium channels?, DIABETOLOGIA, Vol: 39, Pages: 861-864, ISSN: 0012-186X

Journal article

Pickkers P, Garcha R, Schachter M, Hughes ADet al., 1996, Action of thiazides and inhibitors of carbonic anhydrase on tone of guinea-pig isolated small mesenteric arteries, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 118, Pages: P16-P16, ISSN: 0007-1188

Journal article

King LA, Stanton AV, Sever PS, Thom SA, Hughes ADet al., 1996, Arteriolar length-diameter (L:D) ratio: A geometric parameter of the retinal vasculature diagnostic of hypertension, JOURNAL OF HUMAN HYPERTENSION, Vol: 10, Pages: 417-418, ISSN: 0950-9240

Journal article

Hughes AD, 1996, The role of isoprenoids in vascular smooth muscle: Potential benefits of statins unrelated to cholesterol lowering, JOURNAL OF HUMAN HYPERTENSION, Vol: 10, Pages: 387-390, ISSN: 0950-9240

Journal article

Singer DRJ, Hughes AD, 1996, Proceedings of the Seventh Symposium of the London Hypertension Society: New themes in hypertension, JOURNAL OF HUMAN HYPERTENSION, Vol: 10, Pages: 375-376, ISSN: 0950-9240

Journal article

Ibrahim J, Hughes AD, Schachter M, Sever PSet al., 1996, Enhanced tissue polyamine content in the spontaneously hypertensive rat, CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Vol: 23, Pages: 410-414, ISSN: 0305-1870

Journal article

Garcha RS, Schachter M, Sever PS, Hughes ADet al., 1996, Action of losartan, PD-123,319 and endothelial factors on angiotensin-II (AII) responses in human resistance arteries, FASEB JOURNAL, Vol: 10, Pages: 4004-4004, ISSN: 0892-6638

Journal article

Patel MK, Betteridge LJ, Hughes AD, Clunn GF, Schachter M, Shaw RJ, Sever PSet al., 1996, Effect of angiotensin II on the expression of the early growth response gene c-fos and DNA synthesis in human vascular smooth muscle cells, JOURNAL OF HYPERTENSION, Vol: 14, Pages: 341-347, ISSN: 0263-6352

Journal article

Hughes AD, Parkinson NA, Wijetunge S, 1996, α<inf>2</inf>-Adrenoceptor activation increases calcium channel currents in single vascular smooth muscle cells isolated from human omental resistance arteries, Journal of Vascular Research, Vol: 33, Pages: 25-31, ISSN: 1018-1172

Single cells were freshly isolated from human omental resistance arteries using an enzymatic dispersion technique. Calcium channel currents (IBa) were recorded using whole cell voltage clamp techniques with Ba2+ as the charge carrier. BHT 933, a selective α2-adrenoceptor agonist, increased IBa. The effectof BHT 933 was reversible following washout. The action of BHT 933 was blocked by yohimbine. Pretreatment of tissues with pertussis toxin for 18 h or inclusion of GDP-β-S in the intracellular patch pipette solution also prevented the BHT 933-induced rise in IBa, but had no effect on IBa in the absence of BHT 933. Activation of α2-adrenoceptors in human vascular smooth muscle cells increases IBa by a mechanism involving a pertussis toxin-sensitive G protein. © 1996 S. Karger AG, Basel.

Journal article

Hughes AD, Parkinson NA, Wijetunge S, 1996, alpha(2)-Adrenoceptor activation increases calcium channel currents in single vascular smooth muscle cells isolated from human omental resistance arteries, JOURNAL OF VASCULAR RESEARCH, Vol: 33, Pages: 25-31, ISSN: 1018-1172

Journal article

Hughes AD, Betteridge L, Clunn G, Patel M, Schachter M, Wijetunge Set al., 1996, Signals evoked by angiotensin II in vascular smooth muscle cells, International Workshop on Adrenal Glands, Vascular System and Hypertension, Publisher: SOCIETY ENDOCRINOLOGY, Pages: 89-102

Conference paper

Wijetunge S, Hughes AD, 1995, pp60(c-src) increases voltage-operated calcium channel currents in vascular smooth muscle cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 217, Pages: 1039-1044, ISSN: 0006-291X

Journal article

Pickkers P, Russel FGM, Hughes AD, Thien T, Smits Pet al., 1995, Hydrochlorothiazide exerts no direct vasoactivity in the human forearm, 7th European Meeting on Hypertension, Publisher: RAPID SCIENCE PUBLISHERS, Pages: 1833-1836, ISSN: 0263-6352

Conference paper

Stanton AV, Wasan B, Cerutti A, Ford S, Marsh R, Sever PP, Thom SA, Hughes ADet al., 1995, Vascular network changes in the retina with age and hypertension, JOURNAL OF HYPERTENSION, Vol: 13, Pages: 1724-1728, ISSN: 0263-6352

Journal article

Clunn GF, Refson JS, Schachter M, Hughes ADet al., 1995, Different effects of platelet derived growth factor isoforms on DNA synthesis and migration in human vascular smooth muscle cells, 655th Meeting of the Biochemical-Society, Publisher: PORTLAND PRESS, Pages: S608-S608, ISSN: 0300-5127

Conference paper

Clunn GF, Refson JS, Schachter M, Hughes ADet al., 1995, Different effects of platelet derived growth factor isoforms on DNA synthesis and migration in human vascular smooth muscle cells., Biochem Soc Trans, Vol: 23, ISSN: 0300-5127

Journal article

HUGHES AD, BOLTON TB, 1995, ACTION OF ANGIOTENSIN-II, 5-HYDROXYTRYPTAMINE AND ADENOSINE-TRIPHOSPHATE ON IONIC CURRENTS IN SINGLE EAR ARTERY CELLS OF THE RABBIT, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 116, Pages: 2148-2154, ISSN: 0007-1188

Journal article

SINGER DRJ, 1995, NEW THEMES IN HYPERTENSION, JOURNAL OF HUMAN HYPERTENSION, Vol: 9, Pages: 643-644, ISSN: 0950-9240

Journal article

SCHACHTER M, BETTERIDGE LJ, HUGHES AD, PATEL MKet al., 1995, ANGIOTENSIN-II RECEPTORS ARE EXCLUSIVELY OF THE AT(1) SUBTYPE IN CULTURED HUMAN VASCULAR SMOOTH-MUSCLE CELLS, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 23, Pages: S458-S458, ISSN: 0300-5127

Journal article

PICKKERS P, SCHACHTER M, SEVER PS, HUGHES ADet al., 1995, DO K-CA CHANNELS AND CARBONIC-ANHYDRASE PLAY A ROLE IN THIAZIDE-INDUCED HYPERGLYCEMIA, JOURNAL OF HUMAN HYPERTENSION, Vol: 9, Pages: 691-693, ISSN: 0950-9240

Journal article

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