Publications
1335 results found
Topriceanu C-C, Moon J, Hardy R, et al., 2020, LIFE-COURSE FRAILTY AND MULTIMORBIDITY IS HARMFUL FOR THE HEART IN OLDER AGE: RESULTS FROM THE MRC 1946 NSHD BRITISH BIRTH COHORT, Publisher: BMJ PUBLISHING GROUP, Pages: A63-A65, ISSN: 1355-6037
Zalen JV, Badiani S, Silva AD, et al., 2020, Myocardial recruitment and the systolic efficiency slope; how do they relate to exercise performance in healthy young adults?
Timmons JG, Greenlaw N, Stehouwer CD, et al., 2020, Renal Effects of Metformin in Type 1 Diabetes (T1D): The REMOVAL Trial, 80th Scientific Sessions of the American-Diabetes-Association (ADA), Publisher: AMER DIABETES ASSOC, ISSN: 0012-1797
Huang Z, Fonseca R, Sharman JE, et al., 2020, The influence of fitness on exercise blood pressure and its association with cardiac structure in adolescence, SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, Vol: 30, Pages: 1033-1039, ISSN: 0905-7188
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- Citations: 4
Michail M, Hughes AD, Comella A, et al., 2020, Acute Effects of Transcatheter Aortic Valve Replacement on Central Aortic Hemodynamics in Patients With Severe Aortic Stenosis, HYPERTENSION, Vol: 75, Pages: 1557-1564, ISSN: 0194-911X
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- Citations: 9
Hughes AD, Park C, Ramakrishnan A, et al., 2020, Feasibility of estimation of aortic wave intensity using non-invasive pressure recordings in the absence of flow velocity in man, Frontiers in Physiology, Vol: 11, Pages: 1-9, ISSN: 1664-042X
Background: Wave intensity analysis provides valuable information on ventriculo-arterial function, hemodynamics, and energy transfer in the arterial circulation. Widespread use of wave intensity analysis is limited by the need for concurrent measurement of pressure and flow waveforms. We describe a method that can estimate wave intensity patterns using only non-invasive pressure waveforms (pWIA).Methods: Radial artery pressure and left ventricular outflow tract (LVOT) flow velocity waveforms were recorded in 12 participants in the Southall and Brent Revisited (SABRE) study. Pressure waveforms were analyzed using custom-written software to derive the excess pressure (Pxs) which was scaled to peak LVOT velocity and used to calculate wave intensity. These data were compared with wave intensity calculated using the measured LVOT flow velocity waveform. In a separate study, repeat measures of pWIA were performed on 34 individuals who attended two clinic visits at an interval of ≈1 month to assess reproducibility and reliability of the method.Results: Pxs waveforms were similar in shape to aortic flow velocity waveforms and the time of peak Pxs and peak aortic velocity agreed closely. Wave intensity estimated using pWIA showed acceptable agreement with estimates using LVOT velocity tracings and estimates of wave intensity were similar to values reported previously in the literature. The method showed fair to good reproducibility for most parameters.Conclusion: The Pxs is a surrogate of LVOT flow velocity which, when appropriately scaled, allows estimation of aortic wave intensity with acceptable reproducibility. This may enable wider application of wave intensity analysis to large studies.
Bhuva AN, D'Silva A, Hughes AD, et al., 2020, REPLY: Rejuvenating Pheidippides and the Evergreen Benefits of Endurance Training, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 75, Pages: 2278-2279, ISSN: 0735-1097
Imahori Y, Frost C, Mathiesen EB, et al., 2020, Effect of adiposity on differences in carotid plaque burden in studies conducted in Norway and Russia: a cross-sectional analysis of two populations at very different risk of cardiovascular mortality, BMJ OPEN, Vol: 10, ISSN: 2044-6055
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- Citations: 2
Prabhakaran D, Chandrasekaran AM, Singh K, et al., 2020, Yoga-Based Cardiac Rehabilitation After Acute Myocardial Infarction A Randomized Trial, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 75, Pages: 1551-1561, ISSN: 0735-1097
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- Citations: 37
Bhuva AN, Treibel TA, De Marvao A, et al., 2020, Sex and regional differences inmyocardial plasticity in aortic stenosis are revealed by 3D modelmachine learning, EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol: 21, Pages: 417-427, ISSN: 2047-2404
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- Citations: 8
Al Saikhan L, Park C, Tillin T, et al., 2020, SEX-DIFFERENCES IN LEFT VENTRICULAR REMODELLING PATTERN BY 3D ECHOCARDIOGRAPHY IN ASSOCIATION WITH THE LONG-TERM RISK OF ALL-CAUSE MORTALITY: FINDINGS FROM THE SOUTHALL AND BRENT REVISITED (SABRE) STUDY, Conference of American-College-of-Cardiology (ACC) / World Congress of Cardiology (WCC), Publisher: ELSEVIER SCIENCE INC, Pages: 1694-1694, ISSN: 0735-1097
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- Citations: 1
Al Saikhan L, Park C, Tillin T, et al., 2020, THE PREVALENCE OF SUBCLINICAL LEFT VENTRICULAR SYSTOLIC DYSFUNCTION BY 3D-GLOBAL LONGITUDINAL STRAIN IN SOUTH ASIANS COMPARED TO WHITES EUROPEANS AND THE ROLE OF CENTRAL OBESITY: THE SOUTHALL AND BRENT REVISITED (SABRE) STUDY, Conference of American-College-of-Cardiology (ACC) / World Congress of Cardiology (WCC), Publisher: ELSEVIER SCIENCE INC, Pages: 1656-1656, ISSN: 0735-1097
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- Citations: 1
D'Silva A, Bhuva AN, van Zalen J, et al., 2020, Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners, FRONTIERS IN PHYSIOLOGY, Vol: 11, ISSN: 1664-042X
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- Citations: 7
Imahori Y, Mathiesen EB, Morgan KE, et al., 2020, The association between anthropometric measures of adiposity and the progression of carotid atherosclerosis, BMC CARDIOVASCULAR DISORDERS, Vol: 20, ISSN: 1471-2261
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- Citations: 8
Borges MC, Schmidt AF, Jefferis B, et al., 2020, Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants, JOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol: 9, ISSN: 2047-9980
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- Citations: 22
Uejima T, Dunstan FD, Arbustini E, et al., 2020, Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking, JOURNAL OF HUMAN HYPERTENSION, Vol: 34, Pages: 214-222, ISSN: 0950-9240
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- Citations: 31
Uejima T, Dunstan FD, Arbustini E, et al., 2020, Age-specific reference values for carotid arterial stiffness estimated by ultrasonic wall tracking (vol 77, pg 538, 2019), JOURNAL OF HUMAN HYPERTENSION, Vol: 34, Pages: 258-258, ISSN: 0950-9240
Kettunen J, Holmes MV, Allara E, et al., 2020, Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition., PLoS Biol, Vol: 18
[This corrects the article DOI: 10.1371/journal.pbio.3000572.].
Picone DS, Schultz MG, Otahal P, et al., 2020, Influence of Age on Upper Arm Cuff Blood Pressure Measurement, HYPERTENSION, Vol: 75, Pages: 844-850, ISSN: 0194-911X
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- Citations: 24
Jones S, Tillin T, Williams S, et al., 2020, Type 2 diabetes does not account for ethnic differences in exercise capacity or skeletal muscle function in older adults, DIABETOLOGIA, Vol: 63, Pages: 624-635, ISSN: 0012-186X
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- Citations: 4
Buus NH, Carlsen RK, Hughes AD, et al., 2020, Influence of Renal Transplantation and Living Kidney Donation on Large Artery Stiffness and Peripheral Vascular Resistance, AMERICAN JOURNAL OF HYPERTENSION, Vol: 33, Pages: 234-242, ISSN: 0895-7061
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- Citations: 8
Wang J, Tillin T, Hughes AD, et al., 2020, Associations between family history and coronary artery calcium and coronary heart disease in British Europeans and South Asians, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 300, Pages: 39-42, ISSN: 0167-5273
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- Citations: 6
Augusto JB, Knott K, Bhuva A, et al., 2020, The Fabry cardiovascular phenotype: Aortic stiffness in Fabry disease is linked to left ventricular hypertrophy and myocardial inflammation but not storage or fibrosis, MOLECULAR GENETICS AND METABOLISM, Vol: 129, Pages: S23-S23, ISSN: 1096-7192
Kazmi N, Elliott HR, Burrows K, et al., 2020, Associations between high blood pressure and DNA methylation, PLOS ONE, Vol: 15, ISSN: 1932-6203
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- Citations: 29
Hughes AD, Parker KH, 2020, The modified arterial reservoir: an update with consideration of asymptotic pressure (<i>P</i><sub>∞</sub>) and zero-flow pressure (<i>P</i><sub><i>zf</i></sub>)
<jats:title>Abstract</jats:title><jats:p>This article describes the modified arterial reservoir in detail. The modified arterial reservoir makes explicit the wave nature of both reservoir (<jats:italic>P</jats:italic><jats:sub><jats:italic>res</jats:italic></jats:sub>) and excess pressure (<jats:italic>P</jats:italic><jats:sub><jats:italic>xs</jats:italic></jats:sub>). The mathematical derivation and methods for estimating<jats:italic>P</jats:italic><jats:sub><jats:italic>res</jats:italic></jats:sub>in the absence of flow velocity data are described. There is also discussion of zero-flow pressure (<jats:italic>P</jats:italic><jats:sub><jats:italic>zf</jats:italic></jats:sub>), the pressure at which flow through the circulation ceases; its relationship to asymptotic pressure (<jats:italic>P</jats:italic><jats:sub><jats:italic>∞</jats:italic></jats:sub>) estimated by the reservoir model; and the physiological interpretation of<jats:italic>P</jats:italic><jats:sub><jats:italic>zf</jats:italic></jats:sub>. A systematic review and meta-analysis provides evidence that<jats:italic>P</jats:italic><jats:sub><jats:italic>zf</jats:italic></jats:sub>differs from mean circulatory filling pressure.</jats:p>
Hughes AD, Park C, Ramakrishnan A, et al., 2020, Feasibility of estimation of aortic wave intensity using non-invasive pressure recordings in the absence of flow velocity in man
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Wave intensity analysis provides valuable information on ventriculo-arterial function, hemodynamics and energy transfer in the arterial circulation. Widespread use of wave intensity analysis is limited by the need for concurrent measurement of pressure and flow waveforms. We describe a method that can estimate wave intensity patterns using only non-invasive pressure waveforms (pWIA).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Radial artery pressure and left ventricular outflow tract (LVOT) flow velocity waveforms were recorded in 12 participants in the Southall and Brent Revisited (SABRE) study. Pressure waveforms were analysed using custom-written software to derive the excess pressure (<jats:italic>P<jats:sub>xs</jats:sub></jats:italic>) which was scaled to peak LVOT velocity and used to calculate wave intensity. These data were compared with wave intensity calculated using the measured LVOT flow velocity waveform. In a separate study, repeat measures of pWIA were performed on 34 individuals who attended 2 clinic visits at an interval of approximately 1 month to assess reproducibility and reliability of the method.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p><jats:italic>P<jats:sub>xs</jats:sub></jats:italic> waveforms were similar in shape to aortic flow velocity waveforms and the time of peak <jats:italic>P<jats:sub>xs</jats:sub></jats:italic> and peak aortic velocity agreed closely. Wave intensity estimated using pWIA showed acceptable agreement with estimates using LVOT velocity tracings and estimates of wave intensity were similar to values reported previously in the literature. The method showed fair to good reproducibility for most parameters.<
Bhuva AN, D'Silva A, Torlasco C, et al., 2020, Training for a First-Time Marathon Reverses Age-Related Aortic Stiffening, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 75, Pages: 60-71, ISSN: 0735-1097
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- Citations: 23
Huang Z, Sharman JE, Fonseca R, et al., 2020, Masked hypertension and submaximal exercise blood pressure among adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC), SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, Vol: 30, Pages: 25-30, ISSN: 0905-7188
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- Citations: 7
Jones S, Kinsella M, Torlasco C, et al., 2020, Correction to: Improvements in Skeletal Muscle Can Be Detected Using Broadband NIRS in First-Time Marathon Runners.
This chapter was inadvertently published as an open access chapter. However, the open access for this chapter has now been reverted.
Jones S, Kinsella M, Torlasco C, et al., 2020, Improvements in Skeletal Muscle Can Be Detected Using Broadband NIRS in First-Time Marathon Runners, Editors: Ryu, LaManna, Harrison, Lee, Publisher: SPRINGER INTERNATIONAL PUBLISHING AG, Pages: 245-251, ISBN: 978-3-030-34459-7
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- Citations: 1
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