Imperial College London
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Angela Kedgley

Faculty of Engineering, Department of Bioengineering

Reader in Orthopaedic Biomechanics
 
 
 
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Contact

 

+44 (0)20 7594 0747a.kedgley Website

 
 
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Location

 

514BSir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Wai:2023:10.1007/s10237-022-01636-8,
author = {Wai, G and Rusli, W and Ghouse, S and Kieser, DC and Kedgley, A and Newell, N},
doi = {10.1007/s10237-022-01636-8},
journal = {Biomechanics and Modeling in Mechanobiology},
pages = {123--132},
title = {Statistical shape modelling of the thoracic spine for the development of pedicle screw insertion guides},
url = {http://dx.doi.org/10.1007/s10237-022-01636-8},
volume = {22},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Spinal fixation and fusion are surgical procedures undertaken to restore stability in the spine and restrict painful or degenerative motion. Malpositioning of pedicle screws during these procedures can result in major neurological and vascular damage. Patient-specific surgical guides offer clear benefits, reducing malposition rates by up to 25%. However, they suffer from long lead times and the manufacturing process is dependent on third-party specialists. The development of a standard set of surgical guides may eliminate the issues with the manufacturing process. To evaluate the feasibility of this option, a statistical shape model (SSM) was created and used to analyse the morphological variations of the T4–T6 vertebrae in a population of 90 specimens from the Visible Korean Human dataset (50 females and 40 males). The first three principal components, representing 39.7% of the variance within the population, were analysed. The model showed high variability in the transverse process (~ 4 mm) and spinous process (~ 4 mm) and relatively low variation (< 1 mm) in the vertebral lamina. For a Korean population, a standardised set of surgical guides would likely need to align with the lamina where the variance in the population is lower. It is recommended that this standard set of surgical guides should accommodate pedicle screw diameters of 3.5–6 mm and transverse pedicle screw angles of 3.5°–12.4°.
AU  - Wai,G
AU  - Rusli,W
AU  - Ghouse,S
AU  - Kieser,DC
AU  - Kedgley,A
AU  - Newell,N
DO  - 10.1007/s10237-022-01636-8
EP  - 132
PY  - 2023///
SN  - 1617-7940
SP  - 123
TI  - Statistical shape modelling of the thoracic spine for the development of pedicle screw insertion guides
T2  - Biomechanics and Modeling in Mechanobiology
UR  - http://dx.doi.org/10.1007/s10237-022-01636-8
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000857856300002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://link.springer.com/article/10.1007/s10237-022-01636-8
UR  - http://hdl.handle.net/10044/1/100249
VL  - 22
ER  -
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