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@article{van:2017:10.1002/ejhf.921,
author = {van, Bilsen M and Patel, HC and Bauersachs, J and Boehm, M and Borggrefe, M and Brutsaert, D and Coats, AJS and de, Boer RA and de, Keulenaer G and Filippatos, GS and Floras, J and Grassi, G and Jankowska, EA and Kornet, L and Lunde, IG and Maack, C and Mahfoud, F and Pollesello, P and Ponikowski, P and Ruschitzka, F and Sabbah, HN and Schultz, HD and Seferovic, P and Slart, RHJA and Taggart, P and Tocchetti, CG and Van, Laake L and Zannad, F and Heymans, S and Lyon, AR},
doi = {10.1002/ejhf.921},
journal = {European Journal of Heart Failure},
pages = {1361--1378},
title = {The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology},
url = {http://dx.doi.org/10.1002/ejhf.921},
volume = {19},
year = {2017}
}

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TY  - JOUR
AB  - Despite improvements in medical therapy and device-based treatment, heart failure (HF) continues to impose enormous burdens on patients and health care systems worldwide. Alterations in autonomic nervous system (ANS) activity contribute to cardiac disease progression, and the recent development of invasive techniques and electrical stimulation devices has opened new avenues for specific targeting of the sympathetic and parasympathetic branches of the ANS. The Heart Failure Association of the European Society of Cardiology recently organized an expert workshop which brought together clinicians, trialists and basic scientists to discuss the ANS as a therapeutic target in HF. The questions addressed were: (i) What are the abnormalities of ANS in HF patients? (ii) What methods are available to measure autonomic dysfunction? (iii) What therapeutic interventions are available to target the ANS in patients with HF, and what are their specific strengths and weaknesses? (iv) What have we learned from previous ANS trials? (v) How should we proceed in the future?
AU  - van,Bilsen M
AU  - Patel,HC
AU  - Bauersachs,J
AU  - Boehm,M
AU  - Borggrefe,M
AU  - Brutsaert,D
AU  - Coats,AJS
AU  - de,Boer RA
AU  - de,Keulenaer G
AU  - Filippatos,GS
AU  - Floras,J
AU  - Grassi,G
AU  - Jankowska,EA
AU  - Kornet,L
AU  - Lunde,IG
AU  - Maack,C
AU  - Mahfoud,F
AU  - Pollesello,P
AU  - Ponikowski,P
AU  - Ruschitzka,F
AU  - Sabbah,HN
AU  - Schultz,HD
AU  - Seferovic,P
AU  - Slart,RHJA
AU  - Taggart,P
AU  - Tocchetti,CG
AU  - Van,Laake L
AU  - Zannad,F
AU  - Heymans,S
AU  - Lyon,AR
DO  - 10.1002/ejhf.921
EP  - 1378
PY  - 2017///
SN  - 1388-9842
SP  - 1361
TI  - The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
T2  - European Journal of Heart Failure
UR  - http://dx.doi.org/10.1002/ejhf.921
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418670800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/57245
VL  - 19
ER  -

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