Imperial College London
Alternate

PROFESSOR AZEEM MAJEED

Faculty of Medicine, School of Public Health

Chair - Primary Care and Public Health & Head of Department
 
 
 
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Contact

 

+44 (0)20 7594 3368a.majeed Website

 
 
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Assistant

 

Ms Dorothea Cockerell +44 (0)20 7594 3368

 
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Location

 

Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{McKay:2021:10.1111/dom.14344,
author = {McKay, AJ and Gunn, LH and Nugawela, MD and Sathish, T and Majeed, A and Vamos, E and Molina, G and Sivaprasad, S},
doi = {10.1111/dom.14344},
journal = {Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics},
pages = {1322--1330},
title = {Associations between attainment of incentivized primary care indicators and incident sight-threatening diabetic retinopathy in England: A population-based historical cohort study},
url = {http://dx.doi.org/10.1111/dom.14344},
volume = {23},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AimTo examine the impact of attainment of primary care diabetes clinical indicators on progression to sightthreatening diabetic retinopathy (STDR) among those with mild nonproliferative diabetic retinopathy (NPDR).Materials and MethodsAn historical cohort study of 18,978 adults (43.63% female) diagnosed with type 2 diabetes before 1 April 2010 and mild NPDR before 1 April 2011 was conducted. The data were obtained from the UK Clinical Practice Research Datalink during 20102017, provided by 330 primary care practices in England. Exposures included attainment of the Quality and Outcomes Framework HbA1c (≤59 mmol/mol [≤7.5%]), blood pressure (≤140/80 mmHg) and cholesterol (≤5 mmol/L) indicators in the financial year 20102011, as well as the number of National Diabetes Audit processes completed in 20102011. The outcome was time to incident STDR. Nearest neighbour propensity score matching was undertaken, and univariable and multivariable Cox proportional hazards models were then fitted using the matched samples. Concordance statistics were calculated for each model.ResultsA total of 1037 (5.5%) STDR diagnoses were observed over a mean followup of 3.6 (SD 2.0) years. HbA1c, blood pressure and cholesterol indicator attainment were associated with lower rates of STDR (adjusted hazard ratios [95% CI] 0.64 [0.550.74; p < .001], 0.83 [0.720.94; p = .005] and 0.80 [0.660.96; p = .015], respectively).ConclusionsOur findings provide support for meeting appropriate indicators for the management of type 2 diabetes in primary care to bring a range of benefits, including improved health outcomes—such as a reduction in the risk of STDR—for people with type 2 diabetes.
AU  - McKay,AJ
AU  - Gunn,LH
AU  - Nugawela,MD
AU  - Sathish,T
AU  - Majeed,A
AU  - Vamos,E
AU  - Molina,G
AU  - Sivaprasad,S
DO  - 10.1111/dom.14344
EP  - 1330
PY  - 2021///
SN  - 1462-8902
SP  - 1322
TI  - Associations between attainment of incentivized primary care indicators and incident sight-threatening diabetic retinopathy in England: A population-based historical cohort study
T2  - Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
UR  - http://dx.doi.org/10.1111/dom.14344
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000624569000001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14344
UR  - http://hdl.handle.net/10044/1/87658
VL  - 23
ER  -
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