Imperial College London
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Dr Alex Miras

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Visiting Professor
 
 
 
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Contact

 

+44 (0)7958 377 674a.miras

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Akalestou:2022:endrev/bnab022,
author = {Akalestou, E and Miras, A and Rutter, G and Le, Roux C},
doi = {endrev/bnab022},
journal = {Endrocrine Reviews},
pages = {19--34},
title = {Mechanisms of weight loss after obesity surgery},
url = {http://dx.doi.org/10.1210/endrev/bnab022},
volume = {43},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Obesity surgery remains the most effective treatment for obesity and its complications.Weight loss was initially attributed to decreased energy absorption from the gut buthave since been linked to reduced appetitive behaviour and potentially increasedenergy expenditure. Implicated mechanisms associating rearrangement of thegastrointestinal tract with these metabolic outcomes include central appetite control,release of gut peptides, change in microbiota and bile acids. However, the exactcombination and timing of signals remain largely unknown. In this review, we surveyrecent research investigating these mechanisms, and seek to provide insights onunanswered questions over how weight loss is achieved following bariatric surgerywhich may eventually lead to safer, nonsurgical weight-loss interventions orcombinations of medications with surgery
AU  - Akalestou,E
AU  - Miras,A
AU  - Rutter,G
AU  - Le,Roux C
DO  - endrev/bnab022
EP  - 34
PY  - 2022///
SN  - 0163-769X
SP  - 19
TI  - Mechanisms of weight loss after obesity surgery
T2  - Endrocrine Reviews
UR  - http://dx.doi.org/10.1210/endrev/bnab022
UR  - http://hdl.handle.net/10044/1/90968
VL  - 43
ER  -
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