Imperial College London


Faculty of MedicineSchool of Public Health

J-IDEA Research Associate







Building E - Sir Michael UrenWhite City Campus





Publication Type

6 results found

Mishra A, McClelland RL, Inoue LYT, Kerr KFet al., 2021, Recalibration Methods for Improved Clinical Utility of Risk Scores, MEDICAL DECISION MAKING, Vol: 42, Pages: 500-512, ISSN: 0272-989X

Journal article

Hug L, You D, Blencowe H, Mishra A, Wang Z, Fix MJ, Wakefield J, Moran AC, Gaigbe-Togbe V, Suzuki E, Blau DM, Cousens S, Creanga A, Croft T, Hill K, Joseph KS, Maswime S, McClure EM, Pattinson R, Pedersen J, Smith LK, Zeitlin J, Alkema Let al., 2021, Global, regional, and national estimates and trends in stillbirths from 2000 to 2019: a systematic assessment, The Lancet, Vol: 398, Pages: 772-785, ISSN: 0140-6736

Journal article

Mishra A, Bůžková P, Balkus JE, Brown ERet al., 2020, Accounting for informative sampling in estimation of associations between sexually transmitted infections and hormonal contraceptive methods, Statistical Communications in Infectious Diseases, Vol: 0, ISSN: 2194-6310

<jats:title>Abstract</jats:title><jats:p>The relationship between hormonal contraceptive method use and sexually transmitted infections is not well understood. Studies that implement routine screening for STIs among different contraceptive users, such as the ASPIRE HIV-1 prevention trial, can be useful for identifying potential risk factors of STIs. However, the complex nature of non-random data can lead to challenges in estimation of associations for potential risk factors. In particular, if screening for the disease is not random (i. e. it is driven by symptoms or other clinical indicators), estimates of association can suffer from bias, often referred to as informative sampling bias. Time-varying predictors and potential stratification variables can further contribute to difficulty in obtaining unbiased estimates. In this paper, we estimate the association between time- varying contraceptive use and Sexually transmitted infections acquisition, in the presence of informative sampling, by extending the work Buzkova (2010). We use a two-step procedure to jointly model the non-random screening process and sexually transmitted infection risk. In the first step, inverse intensity rate ratios (IIRR) weights are estimated. In the second step, a weighted proportional rate model is fit to estimate the IIRR weighted hazard ratio. We apply the method to evaluate the relationship between hormonal contraception and risk of sexually transmitted infections among women participating in a biomedical HIV-1 prevention trial. We compare our results using the proposed weighted method to those generated using conventional approaches that do not account for potential informative sampling bias or do not use the full potential of the data. Using the IIRR weighted approach we found depot medroxyprogesterone acetate users have a significantly decreased hazard of<jats:italic>Trichomonas vaginalis</jats:italic>acquisition compared to IUD users (hazard ratio:

Journal article

Kiweewa FM, Brown E, Mishra A, Nair G, Palanee-Phillips T, Mgodi N, Nakabiito C, Chakhtoura N, Hillier SL, Baeten JMet al., 2019, Acquisition of Sexually Transmitted Infections among Women Using a Variety of Contraceptive Options: A prospective Study among High-Risk African Women, Journal of the International AIDS Society, ISSN: 1758-2652

Journal article

Akello CA, Bunge KE, Nakabiito C, Mirembe BG, Fowler MG, Mishra A, Marrazzo J, Chirenje ZM, Celum C, Balkus JEet al., 2017, Contraceptive Use and Pregnancy Incidence Among Women Participating in an HIV Prevention Trial, Journal of Women's Health, Vol: 26, Pages: 670-676, ISSN: 1540-9996

Journal article

Balkus JE, Nair G, Montgomery ET, Mishra A, Palanee-Phillips T, Ramjee G, Panchia R, Selepe P, Richardson BA, Chirenje ZM, Marrazzo JMet al., 2015, Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial, JAIDS Journal of Acquired Immune Deficiency Syndromes, Vol: 70, Pages: 212-217, ISSN: 1525-4135

Journal article

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