Summary
Antonis is a postdoctoral research associate at the Medical Research Council (MRC) Centre for Environment and Health, School of Public Health. His current research at Imperial College is focused on emerging contaminants and microplastics in the atmospheric and aquatic environment.
Antonis is an expert in small molecule profiling and quantification, mass spectrometry and multidimensional chromatography. He has developed GC(xGC)-MS methods for the analysis of volatile organic compounds (VOC) in human breath and biofluids for cancer diagnosis. He has also extensively applied metabolomic approaches for the investigation of the link between gut microbiome metabolites and the pathogenesis of cardiometabolic and neurodevelopmental diseases. Some of his previous projects were including analytical method development and application for targeted analyses of biological samples with chromatographic and mass spectrometric techniques (UPLC-MS/MS, GC-MS and DI-MS/MS). Furthermore, he has developed GC(xGC)-MS-based untargeted metabolomic and volatolomic pipelines, applicable from small in-vitro to large-scale molecular epidemiological studies. During his studies, his main research activities were focused on the exposure assessment of endocrine disrupting and neurotoxic chemicals in pregnant women and their children. He developed and applied HPLC-MS methods for the determination of bisphenol-a, parabens, organophosphorous and phthalate metabolites in human urine.
Antonis studied at University of Crete, Greece. He was awarded a PhD in “Environmental and Analytical Chemistry” (2015), a MSc in “Environmental Science and Engineering” (2011) and a BSc in Chemistry (2009).
Publications
Journals
Belluomo I, Whitlock SE, Myridakis A, et al., 2024, Combining Thermal Desorption with Selected Ion Flow Tube Mass Spectrometry for Analyses of Breath Volatile Organic Compounds., Anal Chem, Vol:96, Pages:1397-1401
Myridakis A, Wen Q, Boshier PR, et al., 2023, Global urinary volatolomics with (GC×)GC-TOF-MS, Analytical Chemistry, Vol:95, ISSN:0003-2700, Pages:17170-17176
Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, et al., 2023, Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide, Nature Communications, Vol:14, ISSN:2041-1723, Pages:1-18
Wen Q, Myridakis A, Boshier PR, et al., 2023, A complete pipeline for untargeted urinary volatolomic profiling with sorptive extraction and dual polar and nonpolar column methodologies coupled with gas chromatography time-of-flight mass spectrometry., Analytical Chemistry, Vol:95, ISSN:0003-2700, Pages:758-765
Belda E, Voland L, Tremaroli V, et al., 2022, Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism, Gut, Vol:71, ISSN:0017-5749, Pages:2463-2480