Imperial College London

Dr Antonis Myridakis

Faculty of MedicineDepartment of Surgery & Cancer

Research Associate
 
 
 
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Contact

 

a.myridakis Website

 
 
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Location

 

7N12Commonwealth BuildingHammersmith Campus

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Summary

 

Summary

Antonis is a postdoctoral research associate at the Division of Surgery. His current research at Imperial College is focused on the development of GC(xGC)-MS methods for the analysis of volatile organic compounds (VOC) in human breath and biofluids for cancer diagnosis.

He has also extensively applied metabolomic approaches for the investigation of the link between gut microbiome metabolites and the pathogenesis of cardiometabolic and neurodevelopmental diseases.Some of his previous projects were including analytical method development and application for targeted analyses of biological samples with chromatographic and mass spectrometric techniques (UPLC-MS/MS, GC-MS and DI-MS/MS). Furthermore, he has developed GC-MS-based untargeted metabolomic pipelines from small in-vitro to large-scale molecular epidemiological studies.

During his studies, his main research activities were focused on the exposure assessment of endocrine disrupting and neurotoxic chemicals in pregnant women and their children. He developed and applied HPLC-MS methods for the determination of bisphenol-a, parabens, organophosphorous  and phthalate metabolites in human urine.

Antonis studied at University of Crete, Greece. He was awarded a PhD in “Environmental and Analytical Chemistry” (2015), a MSc in “Environmental Science and Engineering” (2011) and a BSc in Chemistry (2009).

Publications

Journals

Fromentin S, Forslund SK, Chechi K, et al., 2022, Microbiome and metabolome features of the cardiometabolic disease spectrum, Nature Medicine, Vol:28, ISSN:1078-8956, Pages:303-+

Belda E, Voland L, Tremaroli V, et al., 2022, Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism, Gut, ISSN:0017-5749

Forslund SK, Chakaroun R, Zimmermann-Kogadeeva M, et al., 2021, Combinatorial, additive and dose-dependent drug-microbiome associations, Nature, Vol:600, ISSN:0028-0836, Pages:500-+

Nuzzo A, Guedj K, Curac S, et al., 2021, Accuracy of citrulline, I-FABP and d-lactate in the diagnosis of acute mesenteric ischemia, Scientific Reports, Vol:11, ISSN:2045-2322, Pages:1-10

Bermudez-Martin P, Becker JAJ, Caramello N, et al., 2021, The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota, Microbiome, Vol:9, ISSN:2049-2618, Pages:1-23

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