Summary
SUMMARY
I am an Imperial College Research Fellow at the department of Materials. My research interests focus on the design, synthesis and characterization of inorganic nanoparticles and nanocomposites (silica, ceria, SPION and gold) for biomedical applications with particular interest in drug delivery and antioxidant system. The nanocomposite particles are used for the treatment of neuro-degenerative diseases, osteoporosis, cancer and tuberculous meningitis.
Biography
In 2007 I graduated in Pharmaceutical Chemistry at the University of Sassari. I started my adventure in nanobiotechnology with an internship at University of L'Aquila (2008). From 2010 to 2012 I was post-graduate Research Assistant, in the Laboratory of Materials Science and Nanotechnologies led by Prof. P. Innocenzi working with nanomaterials with antioxidant property for biological applications. In 2016 I obtained a PhD in nanochemistry, nanomaterials and functional materials at University of Sassari under the supervision of Prof. L. Malfatti. In 2016 I was awarded a Marie Skłodowska Curie individual fellowship, with a project focused on Inorganic therapeutic nanoparticles for osteoporosis under the supervision of Prof. J.Jones (2016-2018). From 2018 to 2019 I was postdoc at Imperial college working on fluorescent probes with exceptional brightness for early diagnosis of breast cancer under the supervision of Dr. Fang Xie.
During this time, I was also part of exchange projects at the University Hospital of Zurich, working on neurodegeneration in Bovine Spongiform Encephalopathy, and at CSIRO in Melbourne developing skills working on composite materials based on Metal Organic Frameworks and cerium oxide.
I have been visiting researcher at University of Sassari.
Publications
Journals
Morfill C, Pankratova S, Machado P, et al., 2023, Addition to "Nanostars Carrying Multifunctional Neurotrophic Dendrimers Protect Neurons in Preclinical In Vitro Models of Neurodegenerative Disorders"., Acs Appl Mater Interfaces
Mohammed AA, Merrild NG, Li S, et al., 2022, Double-network hydrogels reinforced with covalently bonded silica nanoparticles via 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide chemistry, Acs Omega, Vol:7, ISSN:2470-1343, Pages:43904-43914
Morfill C, Pankratova S, Machado P, et al., 2022, Nanostars Carrying Multifunctional Neurotrophic Dendrimers Protect Neurons in Preclinical In Vitro Models of Neurodegenerative Disorders, Acs Applied Materials & Interfaces, Vol:14, ISSN:1944-8244, Pages:47445-47460
Naruphontjirakul P, Li S, Pinna A, et al., 2022, Interaction of monodispersed strontium containing bioactive glass nanoparticles with macrophages, Biomaterials Advances, Vol:133, ISSN:2772-9508, Pages:1-12
Kumar P, Kalaiarasan G, Porter AE, et al., 2021, An overview of methods of fine and ultrafine particle collection for physicochemical characterisation and toxicity assessments., Science of the Total Environment, Vol:756, ISSN:0048-9697, Pages:1-22