Imperial College London
Alternate

ProfessorAlexandraPorter

Faculty of Engineering, Department of Materials

Professor of Bio-imaging and Analysis
 
 
 
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Contact

 

+44 (0)20 7594 9691a.porter

 
 
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Location

 

B341 Royal School of MinesRoyal School of MinesSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

181 results found

Uchida M, Willits DA, Muller K, Willis AF, Jackiw L, Jutila M, Young MJ, Porter AE, Douglas Tet al., 2009, Intracellular Distribution of Macrophage Targeting Ferritin-Iron Oxide Nanocomposite, ADVANCED MATERIALS, Vol: 21, Pages: 458-+, ISSN: 0935-9648

Journal article

Cheng C, Porter AE, Muller K, Koziol K, Skepper JN, Midgley P, Welland Met al., 2009, Imaging carbon nanoparticles and related cytotoxicity, 10th International Symposium on Inhaled Particles, Publisher: IOP PUBLISHING LTD, ISSN: 1742-6588

Conference paper

Cheng C, Porter AE, Muller K, Koziol K, Skepper JN, Midgley P, Welland Met al., 2009, Imaging carbon nanoparticles and related cytotoxicity, 10th International Symposium on Inhaled Particles, Publisher: IOP PUBLISHING LTD, ISSN: 1742-6588

Conference paper

Uchida M, Terashima M, Kosuge H, Porter AE, Cunningham CH, McConnell MV, Young MJ, Douglas Tet al., 2008, Protein cage architecture as imaging agents for detecting inflammation

Conference paper

Gass MH, Porter AE, 2008, Imaging carbon nanoparticles in cells, Pages: 668-669, ISSN: 1431-9276

Conference paper

Best SM, Porter AE, Thian ES, Huang Jet al., 2008, Bioceramics: Past, present and for the future, JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, Vol: 28, Pages: 1319-1327, ISSN: 0955-2219

Journal article

Balooch G, Yao W, Ager JW, Balooch M, Nalla RK, Porter AE, Ritchie RO, Lane NEet al., 2007, The aminobisphosphonate risedronate preserves localized mineral and material properties of bone in the presence of Glucocorticoids, ARTHRITIS AND RHEUMATISM, Vol: 56, Pages: 3726-3737, ISSN: 0004-3591

Journal article

Porter AE, Gass M, Muller K, Skepper JN, Midgley PA, Welland Met al., 2007, Direct imaging of single-walled carbon nanotubes in cells, Nature Nanotechnology, Vol: 2, Pages: 713-717, ISSN: 1748-3387

The development of single-walled carbon nanotubes for various biomedical applications is an area of great promise. However, the contradictory data on the toxic effects of single-walled carbon nanotubes1–10 highlight the need for alternative ways to study their uptake and cytotoxic effects in cells. Single-walled carbon nanotubes have been shown to be acutely toxic1–3 in a number of types of cells, but the direct observation of cellular uptake of single-walled carbon nanotubes has not been demonstrated previously due to difficulties in discriminating carbon-based nanotubes from carbon-rich cell structures. Here we use transmission electron microscopy and confocal microscopy to image the translocation of single-walled carbon nanotubes into cells in both stained and unstained human cells. The nanotubes were seen to enter the cytoplasm and localize within the cell nucleus, causing cell mortality in a dosedependent manner.

Journal article

Sohn JI, Joo HJ, Porter AE, Choi C-J, Kim K, Kang DJ, Welland MEet al., 2007, Direct observation of the structural component of the metal-insulator phase transition and growth habits of epitaxially grown VO<sub>2</sub> nanowires, NANO LETTERS, Vol: 7, Pages: 1570-1574, ISSN: 1530-6984

Journal article

Porter AE, Gass M, Muller K, Skepper JN, Midgley P, Welland Met al., 2007, Visualizing the uptake of C<sub>60</sub> to the cytoplasm and nucleaus of human monocyte-derived macrophage cells using energy-filtered transmission electron microscopy and electron tomography, ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol: 41, Pages: 3012-3017, ISSN: 0013-936X

Journal article

Porter AE, Gass M, Muller K, Skepper J, Midgley P, Welland Met al., 2007, Direct Imaging of SWNTs in Human Cells., Nature Nanotechnology

Journal article

Nalla RK, Porter AE, Dariao C, Minor AM, Radmilovic V, Stach EA, Tomsia AP, Ritchie ROet al., 2007, Ultrastructural examination of dentin using focused ion-beam cross-sectioning and transmission electron microscopy (vol 36, pg 672, 2005), MICRON, Vol: 38, Pages: 771-771, ISSN: 0968-4328

Journal article

Porter AE, Buckland T, Hing K, Best SM, Bonfield Wet al., 2006, The structure of the bond between silicon-substituted hydroxyapatite bone and porous bioceramic implants, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 78A, Pages: 25-33, ISSN: 1549-3296

Journal article

Porter AE, Muller K, Skepper J, Midgley P, Welland Met al., 2006, Uptake of C<sub>60</sub> by human monocyte macrophages, its localization and implications for toxicity:: Studied by high resolution electron microscopy and electron tomography, ACTA BIOMATERIALIA, Vol: 2, Pages: 409-419, ISSN: 1742-7061

Journal article

Aizawa M, Patel N, Porter AE, Best SM, Bonfield Wet al., 2006, Syntheses of silicon-containing apatite fibres by a homogeneous precipitation method and their characterization, 18th International Symposium on Ceramics in Medicine, Publisher: TRANS TECH PUBLICATIONS LTD, Pages: 1129-1132, ISSN: 1013-9826

Conference paper

Porter AE, 2006, Nanoscale characterization of the interface between bone and hydroxyapatite implants and the effect of silicon on bone apposition, MICRON, Vol: 37, Pages: 681-688, ISSN: 0968-4328

Journal article

Lynn AK, Nakamura T, Patel N, Porter AE, Renouf AC, Laity PR, Best SM, Cameron RE, Shimizu Y, Bonfield Wet al., 2005, Composition-controlled nanocomposites of apatite and collagen incorporating silicon as an osseopromotive agent, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 74A, Pages: 447-453, ISSN: 1549-3296

Journal article

Aizawa M, Porter AE, Best SM, Bonfield Wet al., 2005, Ultrastructural observation of single-crystal apatite fibres, BIOMATERIALS, Vol: 26, Pages: 3427-3433, ISSN: 0142-9612

Journal article

Nalla RK, Porter AE, Daraio C, Minor AM, Radmilovic V, Stach EA, Tomsia AP, Ritchie ROet al., 2005, Ultrastructural examination of dentin using focused ion-beam cross-sectioning and transmission electron microscopy, MICRON, Vol: 36, Pages: 672-680, ISSN: 0968-4328

Journal article

Porter AE, Taak P, Hobbs LW, Coathup MJ, Blunn GW, Spector Met al., 2004, Bone bonding to hydroxyapatite and titanium surfaces on femoral stems retrieved from human subjects at autopsy, BIOMATERIALS, Vol: 25, Pages: 5199-5208, ISSN: 0142-9612

Journal article

Porter AE, Patel N, Skepper JN, Best SM, Bonfield Wet al., 2004, Effect of sintered silicate-substituted hydroxyapatite on remodelling processes at the bone-implant interface, BIOMATERIALS, Vol: 25, Pages: 3303-3314, ISSN: 0142-9612

Journal article

Porter AE, Botelho CM, Lopes MA, Santos JD, Best SM, Bonfield Wet al., 2004, Ultrastructural comparison of dissolution and apatite precipitation on hydroxyapatite and silicon-substituted hydroxyapatite <i>in vitro</i> and <i>in vivo</i>, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 69A, Pages: 670-679, ISSN: 1549-3296

Journal article

Best SM, Patel N, Porter AE, Bonfield Wet al., 2004, A "healthy apatite" for bone repair., Med J Malaysia, Vol: 59 Suppl B, Pages: 129-130, ISSN: 0300-5283

Bone is unique in its ability to adapt structure to functional requirements, but as is all too obvious in an ever-ageing population it is susceptible to a number of degenerative diseases. Therefore there is an increasing need for materials for bone replacement. Clearly, the ideal material with which to replace bone, would be bone itself, but the major problem now facing us is that there is an insufficient supply of the natural bone to satisfy the clinical requirements. Hence, there is a need for the development of chemically synthesised bone graft substitutes

Journal article

Porter AE, Rea SM, Galtrey M, Best SM, Barber ZHet al., 2004, Production of thin film silicon-doped hydroxyapatite via sputter deposition, JOURNAL OF MATERIALS SCIENCE, Vol: 39, Pages: 1895-1898, ISSN: 0022-2461

Journal article

Porter AE, Best SM, Bonfield W, 2004, Ultrastructural comparison of hydroxyapatite and silicon-substituted hydroxyapatite for biomedical applications, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol: 68A, Pages: 133-141, ISSN: 0021-9304

Journal article

Aizawa M, Porter AE, Best SM, Bonfield Wet al., 2004, Microstructural changes of single-crystal apatite fibres during heat treatment, 16th International Symposium on Ceramics in Medicine, Publisher: TRANS TECH PUBLICATIONS LTD, Pages: 915-918, ISSN: 1013-9826

Conference paper

Porter AE, Patel N, Skepper JN, Best SM, Bonfield Wet al., 2003, Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics, BIOMATERIALS, Vol: 24, Pages: 4609-4620, ISSN: 0142-9612

Journal article

Porter AE, Best SM, Bonfield W, 2003, Ultrastructural characterisation of hydroxyapatite and silicon-substituted hydroxyapatite, 15th International Symposium on Ceramics in Medicine, Publisher: TRANS TECH PUBLICATIONS LTD, Pages: 505-508, ISSN: 1013-9826

Conference paper

Aizawa M, Porter AE, Best SM, Bonfield Wet al., 2003, High resolution transmission electron microscopy investigation of single crystal apatite fibres synthesized by a homogeneous precipitation method, 15th International Symposium on Ceramics in Medicine, Publisher: TRANS TECH PUBLICATIONS LTD, Pages: 509-512, ISSN: 1013-9826

Conference paper

Porter AE, Hobbs LW, Rosen VB, Spector Met al., 2002, The ultrastructure of the plasma-sprayed hydroxyapatite-bone interface predisposing to bone bonding, BIOMATERIALS, Vol: 23, Pages: 725-733, ISSN: 0142-9612

Journal article

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