Imperial College London
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DrArulRamasamy

Faculty of Engineering, Department of Bioengineering

Honorary Clinical Senior Lecturer
 
 
 
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a.ramasamy09

 
 
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Location

 

B304BBessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Yang:2017:10.1308/rcsann.2017.0114,
author = {Yang, P and Evans, S and Bali, N and Ramasamy, A and Evans, R and Stevenson, J and Jeys, L and Grimer, R},
doi = {10.1308/rcsann.2017.0114},
journal = {Annals of The Royal College of Surgeons of England},
pages = {568--572},
title = {Malignant bone tumours of the foot},
url = {http://dx.doi.org/10.1308/rcsann.2017.0114},
volume = {99},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Introduction Malignant osseous foot tumours are uncommon. Their oncological outcomes have been poorly documented in the literature so far. The aim of this study was to establish the incidence and to evaluate the oncological outcomes of such patients. Methods Our large orthopaedic oncology database was used to review 70 malignant osseous foot tumour patients. Results The age at diagnosis of malignant osseous foot tumours demonstrated a bimodal distribution peaking in the second and eighth decades of life. Overall, 55 primary malignant bone tumours of the foot (79%) were identified. The median duration from onset of symptoms to diagnosis was 52 weeks (interquartile range [IQR]: 17-104). Eight primary tumours (15%) underwent an accidental excision (ie intralesional excision of a malignant bone tumour where some of the tumour has been left behind, also known as a 'whoops procedure') prior to referral to our unit. Forty-six patients (84%) underwent surgery overall and thirteen of these developed recurrence or metastases. Seven of eight patients with a previous accidental excision underwent amputation. Fifteen osseous metastatic foot lesions were identified. The median length of foot symptoms to diagnosis was 24 weeks (IQR: 20-36 weeks). The median time to death following diagnosis of osseous foot metastases was 20.1 months (IQR: 11.3-27.8 months). Conclusions A high index of suspicion and awareness of clinical features of malignant osseous foot tumours are both essential to avoid diagnostic delays. Amputation is associated with a respectable outcome for patients who have undergone previous accidental excisions.
AU  - Yang,P
AU  - Evans,S
AU  - Bali,N
AU  - Ramasamy,A
AU  - Evans,R
AU  - Stevenson,J
AU  - Jeys,L
AU  - Grimer,R
DO  - 10.1308/rcsann.2017.0114
EP  - 572
PY  - 2017///
SN  - 0035-8843
SP  - 568
TI  - Malignant bone tumours of the foot
T2  - Annals of The Royal College of Surgeons of England
UR  - http://dx.doi.org/10.1308/rcsann.2017.0114
UR  - https://www.ncbi.nlm.nih.gov/pubmed/28853588
UR  - http://hdl.handle.net/10044/1/58690
VL  - 99
ER  -
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