Publications
274 results found
Newland A, Berney D, Rockall AG, 2012, The adrenal, Images in Urology: Diagnosis and Management, Pages: 121-145, ISBN: 9780857297686
These are images of normal adrenal glands. 1. What is the size of the normal adrenal gland? 2. What is the arterial supply and venous drainage of the right and left adrenal gland? 3. Name the different layers of the adrenal gland shown in Fig. 3.1.3, their embryonic derivation and the main hormones produced within each.
Ramage JK, Ahmed A, Ardill J, et al., 2012, Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs), GUT, Vol: 61, Pages: 6-32, ISSN: 0017-5749
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- Citations: 406
Sundin A, Rockall A, 2012, Therapeutic Monitoring of Gastroenteropancreatic Neuroendocrine Tumors: The Challenges Ahead, NEUROENDOCRINOLOGY, Vol: 96, Pages: 261-271, ISSN: 0028-3835
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- Citations: 43
Bharwani N, Miquel ME, Sahdev A, et al., 2011, Diffusion-weighted imaging in the assessment of tumour grade in endometrial cancer, BRITISH JOURNAL OF RADIOLOGY, Vol: 84, Pages: 997-1004, ISSN: 0007-1285
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- Citations: 58
Kayani I, Avril N, Bomanji J, et al., 2011, Sequential FDG-PET/CT as a Biomarker of Response to Sunitinib in Metastatic Clear Cell Renal Cancer, CLINICAL CANCER RESEARCH, Vol: 17, Pages: 6021-6028, ISSN: 1078-0432
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- Citations: 92
Roberts C, Liyanage SH, Harry VN, et al., 2011, Functional imaging for assessing tumor response in cancer of the cervix., Womens Health (Lond), Vol: 7, Pages: 487-497
Treatment options for carcinoma of the cervix are guided by tumor stage, and include radical surgery, in cases where the tumor is confined to the cervix, or concurrent chemotherapy and radiotherapy. In those cases treated with chemoradiation, the ability to monitor the response to treatment in order to adapt the management plan during its course may be beneficial. This approach has the potential to offer an individualized treatment plan, allowing for differences in behavior between tumors to be addressed early, rather than a 'one size fits all' treatment approach. This article aims to review the use of evolving functional imaging techniques including diffusion-weighted MRI, dynamic contrast-enhanced MRI, and PET as tools for the evaluation of response to treatment of uterine cervical carcinoma.
Bharwani N, Rockall AG, Sahdev A, et al., 2011, Adrenocortical Carcinoma: The Range of Appearances on CT and MRI, AMERICAN JOURNAL OF ROENTGENOLOGY, Vol: 196, Pages: W706-W714, ISSN: 0361-803X
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- Citations: 108
Bharwani N, Reznek RH, Rockall AG, 2011, Ovarian Cancer Management: The role of imaging and diagnostic challenges, EUROPEAN JOURNAL OF RADIOLOGY, Vol: 78, Pages: 41-51, ISSN: 0720-048X
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- Citations: 45
Powles T, Chowdhury S, Avril N, et al., 2011, Sequential FDG-PET/CT as a surrogate marker of response to sunitinib in metastatic clear cell renal cancer, Publisher: AMER SOC CLINICAL ONCOLOGY, ISSN: 0732-183X
Sala E, Rockall A, Kubik-Huch RA, 2011, Advances in magnetic resonance imaging of endometrial cancer, EUROPEAN RADIOLOGY, Vol: 21, Pages: 468-473, ISSN: 0938-7994
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- Citations: 44
Powles T, Blank C, Chowdhury S, et al., 2011, THE OUTCOME OF PATIENTS TREATED WITH UPFRONT SUNITINIB PRIOR TO NEPHRECTOMY IN METASTATIC CLEAR CELL RENAL CANCER, Publisher: ELSEVIER SCIENCE BV, Pages: 102-103, ISSN: 1569-9056
Desouza NM, Sala E, Kyriazi S, et al., 2011, Functional imaging: From tumour biology to the clinic, Gynaecological Cancers: Biology and Therapeutics, Pages: 183-202, ISBN: 9781906985448
The increasing demand for in vivo imaging to provide early biomarkers of disease response as well as to report on predictive and prognostic features of tumours is driving the need for a combined structural and functional approach. Morphological imaging is usually only useful in assessing response late after therapy and, while volumetric measures, for example in cervical cancer, are crucial prognostic indicators, their use in small, early-stage disease is less useful in this regard. With the advent of techniques such as dynamic contrast-enhanced (DCE) computed tomography (CT) or magnetic resonance imaging (MRI), diffusion-weighted (DW) imaging, lymph node-specific contrast agents and positron emission tomography (PET) with F-FDG or other targeted radiotracers, there is a burgeoning field of ‘functional’ techniques that can be exploited for use in the clinic. This chapter describes the range of techniques available, their relationship to tumour biology and their utility in the context of patient management pathways.Available techniques.Dynamic contrast-enhanced CT or MRI.The microvascular properties of tissue can be interrogated with DCE-CT or DCE-MRI, where rapid image acquisition before, during and after a bolus of intravenously injected contrast agent enables pharmacokinetic modelling of its passage through the circulation and into the tissue compartment. The presence of the contrast agent (iodinated in the case of CT, weakly paramagnetic in the case of MRI) increases X-ray attenuation or signal intensity, respectively; the degree of enhancement is determined by blood flow, vascular density, capillary permeability and capillary surface area in the early vascular phase and by extravascular space volume in the interstitial phase.
Salaa E, Rockall A, Rangarajan D, et al., 2010, The role of dynamic contrast-enhanced and diffusion weighted magnetic resonance imaging in the female pelvis, EUROPEAN JOURNAL OF RADIOLOGY, Vol: 76, Pages: 367-385, ISSN: 0720-048X
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- Citations: 125
Bharwani N, Newland A, Tunariu N, et al., 2010, MRI Appearances of Uterine Malignant Mixed Mullerian Tumors, AMERICAN JOURNAL OF ROENTGENOLOGY, Vol: 195, Pages: 1268-1275, ISSN: 0361-803X
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- Citations: 36
Patel S, Liyanage SH, Sahdev A, et al., 2010, Imaging of endometrial and cervical cancer., Insights Imaging, Vol: 1, Pages: 309-328, ISSN: 1869-4101
In this article we review the ever increasing role of imaging in endometrial and cervical cancer. Magnetic resonance imaging (MRI) has emerged as the most widely used technique in the management of women with gynaecological cancer. In endometrial cancer, MRI is reliable in identifying myometrial and cervical invasion and extra-uterine disease, thereby informing preoperative surgical planning. In cervical cancer, MRI plays a crucial role in distinguishing early from advanced disease, thereby stratifying patients for surgery and chemoradiation. MRI is also valuable in assessing proximal extension of cervical tumours in young women with early stage disease for feasibility of fertility preserving surgery. In both cancers, imaging is used for diagnosing nodal metastases, detection of recurrence, and dealing with complications of both the disease and treatment.
Bats A-S, Rockall AG, Singh N, et al., 2010, Perforation of a malignant ovarian tumor into the recto-sigmoid colon, ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, Vol: 89, Pages: 1362-1363, ISSN: 0001-6349
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- Citations: 7
Lai G, Rockall AG, 2010, Lymph Node Imaging in Gynecologic Malignancy, SEMINARS IN ULTRASOUND CT AND MRI, Vol: 31, Pages: 363-376, ISSN: 0887-2171
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- Citations: 14
Dilks P, Narayanan P, Reznek R, et al., 2010, Can quantitative dynamic contrast-enhanced MRI independently characterize an ovarian mass?, EUROPEAN RADIOLOGY, Vol: 20, Pages: 2176-2183, ISSN: 0938-7994
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- Citations: 33
Druce MR, Muthuppalaniappan VM, O'Leary B, et al., 2010, Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation (vol 162, 971, 2010), EUROPEAN JOURNAL OF ENDOCRINOLOGY, Vol: 162, Pages: 1165-1165, ISSN: 0804-4643
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- Citations: 1
Bharwani N, Miquel M, Sahdev A, et al., 2010, Diffusion-Weighted MRI in the Assessment of Tumor Response to Novel Targeted Therapies in Metastatic Renal Cell Carcinoma, 110th Annual Meeting of the American-Roentgen-Ray-Society, Publisher: AMER ROENTGEN RAY SOC, ISSN: 0361-803X
Narayanan P, Sohaib A, Sahdev A, et al., 2010, MRI of Small Adnexal Masses, 110th Annual Meeting of the American-Roentgen-Ray-Society, Publisher: AMER ROENTGEN RAY SOC, ISSN: 0361-803X
Druce MR, Muthuppalaniappan VM, O'Leary B, et al., 2010, Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation, EUROPEAN JOURNAL OF ENDOCRINOLOGY, Vol: 162, Pages: 971-978, ISSN: 0804-4643
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- Citations: 50
Jahan N, Narayanan P, Rockall A, 2010, Magnetic resonance lymphography in gynaecological malignancies, CANCER IMAGING, Vol: 10, Pages: 85-96, ISSN: 1740-5025
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- Citations: 5
Liyanage SH, Roberts CA, Rockall AG, 2010, MRI and PET scans for primary staging and detection of cervical cancer recurrence., Womens Health (Lond), Vol: 6, Pages: 251-267
Worldwide, cervical cancer is the second most common malignancy in women, and is a major cause of morbidity and mortality. Accurate tumor staging is essential for optimal treatment planning and prognosis. Cervical cancer is staged by clinical examination according to the International Federation of Gynecology and Obstetrics staging system. However, clinical staging has inherent deficiencies in evaluating several parameters that are critical for treatment planning. It is now widely accepted that cross-sectional imaging, and in particular MRI, has an important role to play in the staging of these tumors. MRI is an excellent modality for depicting invasive cervical cancer: it can provide objective measurement of tumor size and provides a high negative predictive value for parametrial invasion and stage IVA disease. MRI and positron emission tomography (PET)/computed tomography (CT) play key roles in identifying recurrent disease. PET/CT is also useful in detecting nodal and distant metastases and in radiotherapy planning. Diffusion-weighted MRI is an emerging imaging technique that is currently being evaluated for the detection of primary and recurrent disease and in the assessment of treatment response.
Druce MR, Bharwani N, Akker SA, et al., 2010, Intra-abdominal fibrosis in a recent cohort of patients with neuroendocrine ('carcinoid') tumours of the small bowel, QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, Vol: 103, Pages: 177-185, ISSN: 1460-2725
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- Citations: 43
Jacques AE, Sahdev A, Sandrasagara M, et al., 2009, Reply to letter to the Editor re: Adrenal pheochromocytoma: correlation of MRI appearances with histology and function, EUROPEAN RADIOLOGY, Vol: 19, Pages: 2312-2313, ISSN: 0938-7994
Narayanan P, Iyngkaran T, Sohaib SA, et al., 2009, Pearls and Pitfalls of MR Lymphography in Gynecologic Malignancy, RADIOGRAPHICS, Vol: 29, Pages: 1057-U22, ISSN: 0271-5333
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- Citations: 20
Narayanan P, Nobbenhuis M, Reynolds KM, et al., 2009, Fistulas in Malignant Gynecologic Disease: Etiology, Imaging, and Management, RADIOGRAPHICS, Vol: 29, Pages: 1073-U27, ISSN: 0271-5333
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- Citations: 60
Druce M, Rockall A, Grossman AB, 2009, Fibrosis and carcinoid syndrome: from causation to future therapy, NATURE REVIEWS ENDOCRINOLOGY, Vol: 5, Pages: 276-283, ISSN: 1759-5029
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- Citations: 70
Bharwani N, Jelbert A, Tunariu N, et al., 2009, MR Imaging Features of Uterine Sarcomas, 109th Annual Meeting of the American-Roentgen-Ray-Society, Publisher: AMER ROENTGEN RAY SOC, ISSN: 0361-803X
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