Imperial College London
Portrait Picture

ProfessorAndreaRockall

Faculty of Medicine, Department of Surgery & Cancer

Clinical Chair in Radiology
 
 
 
//

Contact

 

a.rockall

 
 
//

Location

 

ICTEM buildingHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Barnes:2018:10.1259/bjr.20170577,
author = {Barnes, A and Alonzi, R and Blackledge, M and Charles-Edwards, G and Collins, DJ and Cook, G and Coutts, G and Goh, V and Graves, M and Kelly, C and Koh, D-M and McCallum, H and Miquel, ME and O'Connor, J and Padhani, A and Pearson, R and Priest, A and Rockall, A and Stirling, J and Taylor, S and Tunariu, N and van, der Meulen J and Walls, D and Winfield, J and Punwani, S},
doi = {10.1259/bjr.20170577},
journal = {British Journal of Radiology},
pages = {1--12},
title = {UK quantitative WB-DWI technical workgroup: consensus meeting recommendations on optimisation, quality control, processing and analysis of quantitative whole-body diffusion-weighted imaging for cancer},
url = {http://dx.doi.org/10.1259/bjr.20170577},
volume = {91},
year = {2018}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objective: Application of whole body diffusion-weightedMRI (WB-DWI) for oncology are rapidly increasingwithin both research and routine clinical domains.However, WB-DWI as a quantitative imaging biomarker(QIB) has significantly slower adoption. To date, challenges relating to accuracy and reproducibility, essentialcriteria for a good QIB, have limited widespread clinicaltranslation. In recognition, a UK workgroup was established in 2016 to provide technical consensus guidelines(to maximise accuracy and reproducibility of WB-MRIQIBs) and accelerate the clinical translation of quantitative WB-DWI applications for oncology.Methods: A panel of experts convened from cancercentres around the UK with subspecialty expertise inquantitative imaging and/or the use of WB-MRI withDWI. A formal consensus method was used to obtainconsensus agreement regarding best practice. Questionswere asked about the appropriateness or otherwise onscanner hardware and software, sequence optimisation,acquisition protocols, reporting, and ongoing qualitycontrol programs to monitor precision and accuracy andagreement on quality control.Results: The consensus panel was able to reach consensuson 73% (255/351) items and based on consensus areasmade recommendations to maximise accuracy andreproducibly of quantitative WB-DWI studies performedat 1.5T. The panel were unable to reach consensus onthe majority of items related to quantitative WB-DWIperformed at 3T.Conclusion: This UK Quantitative WB-DWI TechnicalWorkgroup consensus provides guidance on maximising accuracy and reproducibly of quantitative WB-DWIfor oncology. The consensus guidance can be usedby researchers and clinicians to harmonise WB-DWIprotocols which will accelerate clinical translation ofWB-DWI-derived QIBs.
AU  - Barnes,A
AU  - Alonzi,R
AU  - Blackledge,M
AU  - Charles-Edwards,G
AU  - Collins,DJ
AU  - Cook,G
AU  - Coutts,G
AU  - Goh,V
AU  - Graves,M
AU  - Kelly,C
AU  - Koh,D-M
AU  - McCallum,H
AU  - Miquel,ME
AU  - O'Connor,J
AU  - Padhani,A
AU  - Pearson,R
AU  - Priest,A
AU  - Rockall,A
AU  - Stirling,J
AU  - Taylor,S
AU  - Tunariu,N
AU  - van,der Meulen J
AU  - Walls,D
AU  - Winfield,J
AU  - Punwani,S
DO  - 10.1259/bjr.20170577
EP  - 12
PY  - 2018///
SN  - 0007-1285
SP  - 1
TI  - UK quantitative WB-DWI technical workgroup: consensus meeting recommendations on optimisation, quality control, processing and analysis of quantitative whole-body diffusion-weighted imaging for cancer
T2  - British Journal of Radiology
UR  - http://dx.doi.org/10.1259/bjr.20170577
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418636700028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.birpublications.org/doi/10.1259/bjr.20170577
UR  - http://hdl.handle.net/10044/1/77712
VL  - 91
ER  -
Download