Summary
My career aim is to understand the water oxidising enzyme Photosystem II in terms of its mechanism, its assembly and its evolutionary relationships with other photosynthetic reaction centres. This enzyme has become the focus of attention because cheap water splitting catalysts are urgently needed in the energy sector for solar fuel production, electrolysis of water and the reverse reaction in fuel cells. My research has made major contributions to understanding this enzyme before it was either popular or profitable. Now that it is finally becoming both of those, I hope to continue to do more of the same. Not just because it might contribute to solving aspects of the energy crisis but also because understanding the enzyme, which put the energy into the biosphere, the oxygen into the atmosphere and thence changed the planet, is one of the greatest challenges in biology and chemistry. It is also a fun enzyme to work on.
Publications
Journals
De Causmaecker S, Douglass J, Fantuzzi A, et al., Energetics of the exchangeable quinone, QB, in Photosystem II, Proceedings of the National Academy of Sciences of Usa, ISSN:0027-8424
Cardona Londono T, Rutherford AW, Evolution of photochemical reaction centres: more twists?, Trends in Plant Science, ISSN:1878-4372
Varghese F, Kabasakal BV, Cotton CA, et al., 2019, A low-potential terminal oxidase associated with the iron-only nitrogenase from the nitrogen-fixing bacterium Azotobacter vinelandii, Journal of Biological Chemistry, ISSN:0021-9258
Takegawa Y, Nakamura M, Nakamura S, et al., 2019, New insights on ChlD1 function in Photosystem II from site-directed mutants of D1/T179 in Thermosynechococcus elongatus, Biochimica Et Biophysica Acta - Bioenergetics, Vol:1860, ISSN:0005-2728, Pages:297-309
Cardona Londono T, Sanchez-Baracaldo P, Rutherford AW, et al., 2019, Early Archean origin of Photosystem II, Geobiology, Vol:17, ISSN:1472-4669, Pages:127-150