Publications
235 results found
Browne HAK, Adams L, Simonds AK, et al., 2003, Ageing does not influence the sleep-related decrease in the hypercapnic ventilatory response, EUROPEAN RESPIRATORY JOURNAL, Vol: 21, Pages: 523-529, ISSN: 0903-1936
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- Citations: 38
Simonds AK, 2003, Ethics and decision making in end stage lung disease, THORAX, Vol: 58, Pages: 272-277, ISSN: 0040-6376
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- Citations: 37
Manzur AY, Muntoni F, Simonds A, 2003, Muscular dystrophy campaign sponsored workshop: recommendation for respiratory care of children with spinal muscular atrophy type II and III. 13th February 2002, London, UK., Neuromuscul Disord, Vol: 13, Pages: 184-189, ISSN: 0960-8966
Lloyd-Owen SJ, Elliott MW, Simonds AK, et al., 2002, A survey of Home Mechanical Ventilation in the UK, Winter Meeting of the British-Thoracic-Society, Publisher: BRITISH MED JOURNAL PUBL GROUP, ISSN: 0040-6376
Simonds AK, 2002, Long-term ventilation in obstructive ventilatory disorders., Respir Care Clin N Am, Vol: 8, Pages: 533-544, ISSN: 1078-5337
A large randomized, controlled study of NIV plus LTOT versus LTOT in patients with COPD is needed that evaluates morbidity, mortality, quality of life, and health economic impact. It is to be hoped that funding for this type of study will be forthcoming. In the meantime, it reasonably can be concluded from existing evidence that domiciliary NIV is unlikely to be effective in most patients with stable COPD, particularly if they are normocapnic. A subgroup of patients with severe hypercapnia, poor tolerance of LTOT, marked nocturnal hypoventilation, or recurrent infective exacerbations may benefit from domiciliary NIV. Systematic evaluation is required in patients with CF or bronchiectasis.
Hart N, Hunt A, Polkey MI, et al., 2002, Comparison of proportional assist ventilation and pressure support ventilation in chronic respiratory failure due to neuromuscular and chest wall deformity, THORAX, Vol: 57, Pages: 979-981, ISSN: 0040-6376
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- Citations: 14
Simonds AK, 2002, Respiratory complications of the muscular dystrophies, SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 23, Pages: 231-238, ISSN: 1069-3424
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- Citations: 28
Tan YK, L'Estrange PR, Luo YM, et al., 2002, Mandibular advancement splints and continuous positive airway pressure in patients with obstructive sleep apnoea: a randomized cross-over trial, EUROPEAN JOURNAL OF ORTHODONTICS, Vol: 24, Pages: 239-249, ISSN: 0141-5387
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- Citations: 119
Simonds AK, 2002, Nocturnal ventilation in neuromuscular disease--when and how?, Monaldi Arch Chest Dis, Vol: 57, Pages: 273-276, ISSN: 1122-0643
While much evidence has been gained over the last decade to support the use of non-invasive ventilation (NIV) in a series of acute and chronic applications, some issues still need to be addressed, particularly regarding the timing of initiation of NIV and the best methods of implementation. This article discusses the role of NIV, if any, in preventing respiratory decline, as a physiotherapy adjunct, and in perioperative care for adults and children with neuromuscular disease.
Nickol AH, Hart N, Ross ET, et al., 2001, Increased day time ventilatory drive following initiation on nocturnal non-invasive ventilation (NIV), THORAX, Vol: 56, Pages: 27-27, ISSN: 0040-6376
Browne HAK, Simonds A, Morrell MJ, 2001, Changes in end expiratory lung volume may influence the therapeutic level of continuous positive airway pressure required in the elderly, THORAX, Vol: 56, Pages: 27-27, ISSN: 0040-6376
Chatwin M, Ross F, Hart N, et al., 2001, A comparison of the effect of mechanical insufflation-exsufflation (MIE), non-invasive ventilation (NIV), and physiotherapy assistance on peak cough flow (PCF) in neuromuscular disease, THORAX, Vol: 56, Pages: 48-49, ISSN: 0040-6376
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- Citations: 1
Bennett JR, Dunroy HMA, Hart N, et al., 2001, Rem sleep-related accessory respiratory muscle activity: Neuronal plasticity in isolated bilateral diaphragm paralysis patients?, THORAX, Vol: 56, Pages: 46-46, ISSN: 0040-6376
Browne HAK, Adams L, Simonds AK, et al., 2001, The influence of ageing on the ventilatory response to hypercapnia in humans during sleep under conditions of controlled upper airway resistance, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 533, Pages: 107P-107P, ISSN: 0022-3751
Browne HAK, Adams L, Simonds AK, et al., 2001, Impact of age on breathing and resistive pressure in people with and without sleep apnea, JOURNAL OF APPLIED PHYSIOLOGY, Vol: 90, Pages: 1074-1082, ISSN: 8750-7587
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- Citations: 15
Murtuza B, Keogh BF, Simonds AK, et al., 2001, Lung volume reduction surgery in a ventilated patient with severe pulmonary emphysema, ANNALS OF THORACIC SURGERY, Vol: 71, Pages: 1037-1038, ISSN: 0003-4975
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- Citations: 2
Simonds AK, 2001, Managing obstructive sleep apnoea., Practitioner, Vol: 245, Pages: 117-120, ISSN: 0032-6518
Nickol AH, Hart N, Moxham J, et al., 2000, Methods of assessing central ventilatory drive in patients with COPD during Co<sub>2</sub> rebreathing, THORAX, Vol: 55, Pages: A77-A77, ISSN: 0040-6376
Browne HAK, Adams L, Simonds AK, et al., 2000, The impact of sleep apnea on arousals from sleep and associated daytime sleepiness is not age dependent, THORAX, Vol: 55, Pages: A53-A53, ISSN: 0040-6376
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- Citations: 1
Jones M, Morrell MJ, Simonds AK, 2000, Inhalation of CO2 reverses sleep apnoea/cheyne stokes respiration in patient's with congestive heart failue but does not improve sleep, THORAX, Vol: 55, Pages: A24-A24, ISSN: 0040-6376
Simonds AK, Ward S, Heather S, et al., 2000, Outcome of paediatric domiciliary mask ventilation in neuromuscular and skeletal disease, EUROPEAN RESPIRATORY JOURNAL, Vol: 16, Pages: 476-481, ISSN: 0903-1936
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- Citations: 94
Simonds AK, 2000, New developments in the treatment of obstructive sleep apnoea., Thorax, Vol: 55 Suppl 1, Pages: S45-S50, ISSN: 0040-6376
Morrell MJ, Browne HAK, Simonds AK, et al., 2000, The impact of EEG arousals on daytime sleepiness in elderly people with and without sleep apnoea, JOURNAL OF PHYSIOLOGY-LONDON, Vol: 525, Pages: 30P-30P, ISSN: 0022-3751
Simonds AK, 2000, Nasal ventilation in progressive neuromuscular disease: experience in adults and adolescents., Monaldi Arch Chest Dis, Vol: 55, Pages: 237-241, ISSN: 1122-0643
A nihilistic approach to ventilatory support in progressive neuromuscular disorders is no longer acceptable. Noninvasive ventilation may improve survival and quality of life in some patients. In other situations, worthwhile palliation of symptoms of nocturnal hypoventilation and dyspnoea may be achieved. Noninvasive ventilation combined with cough assistance may obviate the need for tracheostomy ventilation, or can be employed as part of a staged approach. Individual titration of ventilatory support to meet the needs of the individual and family is vital. The participation of the patient, family and carers in decision-making is crucial and advanced directives are likely to be used increasingly.
Simonds AK, 2000, Nasal ventilation: where are we?, Monaldi Arch Chest Dis, Vol: 55, Pages: 45-49, ISSN: 1122-0643
Simonds AK, 1999, Respiratory high dependency unit care in the UK., Monaldi Arch Chest Dis, Vol: 54, Pages: 444-447, ISSN: 1122-0643
Simonds AK, 1999, Duchenne muscular dystrophy - Reply, THORAX, Vol: 54, Pages: 564-564, ISSN: 0040-6376
Simonds AK, 1999, Curbside Consult: Why do people yawn?, West J Med, Vol: 170, ISSN: 0093-0415
Simonds AK, 1999, Why do people yawn?, WESTERN JOURNAL OF MEDICINE, Vol: 170, Pages: 283-283, ISSN: 0093-0415
Myatt HM, Croft CB, Kotecha BT, et al., 1999, A three-centre prospective pilot study to elucidate the effect of uvulopalatopharyngoplasty on patients with mild obstructive sleep apnoea due to velopharyngeal obstruction, CLINICAL OTOLARYNGOLOGY, Vol: 24, Pages: 95-103, ISSN: 1749-4478
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- Citations: 9
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