Imperial College London

DrAlekosSimoni

Faculty of Natural SciencesDepartment of Life Sciences (Silwood Park)

 
 
 
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Contact

 

+44 (0)20 7589 5111 ext 55409a.simoni

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Simoni:2014:10.1126/science.1245710,
author = {Simoni, A and Wolfgang, W and Topping, MP and Kavlie, RG and Stanewsky, R and Albert, JT},
doi = {10.1126/science.1245710},
journal = {Science},
pages = {525--528},
title = {A Mechanosensory Pathway to the <i>Drosophila</i> Circadian Clock},
url = {http://dx.doi.org/10.1126/science.1245710},
volume = {343},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - <jats:title>Coordinating the Clock</jats:title> <jats:p> In flies, the mechanosensory chordotonal organs help to coordinate the effects of temperature on circadian cycles. <jats:bold> Simoni <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6170" page="525" related-article-type="in-this-issue" vol="343" xlink:href="10.1126/science.1245710">525</jats:related-article> ) provide a mechanism by which mechanosensory input is processed to help to synchronize the biological clock in <jats:italic>Drosophila melanogaster</jats:italic> . The chordotonal organs, which have similarities to the mammalian ear, were also required for sensation of a vibration stimulus and its effects on the endogenous brain clock. The chordotonal organs, present in the joints of the limbs, provide neuronal signals that allow the animal to sense its position or posture—and thus might mediate feedback of a range of behaviors onto the endogenous biological clock. </jats:p>
AU - Simoni,A
AU - Wolfgang,W
AU - Topping,MP
AU - Kavlie,RG
AU - Stanewsky,R
AU - Albert,JT
DO - 10.1126/science.1245710
EP - 528
PY - 2014///
SN - 0036-8075
SP - 525
TI - A Mechanosensory Pathway to the <i>Drosophila</i> Circadian Clock
T2 - Science
UR - http://dx.doi.org/10.1126/science.1245710
VL - 343
ER -