Summary
Alex is a PhD student within the Institute of Chemical Biology (ICB), Department of Chemistry. He is supervised by Prof Alan Spivey and Prof Thomas Brand. In addition he is also co-supervised by Dr Mark Pfuhl (Kings College London) and Dr Katie Chapman (previously Domainex). He joined the ICB in 2017 to first complete an MRes in Chemical Biology before beginning his PhD research in 2018. Previously, Alex was at the University of Bath where he obtained an MSci Natural Sciences, including one year working as a formulation scientist at GlaxoSmithKline.
Alex's research focuses on the Popeye domain containing (POPDC) protein family, a novel class of cAMP effector proteins; specifically the development of novel, small-molecule ligands and the protein-protein interactions of the POPDC family.
Publications
Journals
Swan A, Schindler R, Savarese M, et al., 2023, Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking, Acta Neuropathologica Communications, Vol:11, ISSN:2051-5960, Pages:1-25
Amunjela J, Swan A, Brand T, 2019, The role of the Popeye domain containing gene family in organ homeostasis, Cells, Vol:8, ISSN:2073-4409
Swan A, Gruscheski L, Boland L, et al., 2019, The Popeye domain containing gene family encoding a family of cAMP-effector proteins with important functions in striated muscle and beyond, Journal of Muscle Research and Cell Motility, Vol:40, ISSN:0142-4319, Pages:169-183
Odyniec ML, Sedgwick AC, Swan AH, et al., 2018, 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte, Chemical Communications, Vol:54, ISSN:1359-7345, Pages:8466-8469