Imperial College London

Dr Alejandra Tomas

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Senior Lecturer



+44 (0)20 7594 3364a.tomas-catala Website CV




329ICTEM buildingHammersmith Campus




Group Members

Dr Stavroula Bitsi (Postdoctoral Research Associate)

Ms Yusman Manchanda (Research Coordinator)

Ms Liliane El Eid (PhD Student)

Ms Affiong Oqua (PhD Student)

Research Grants

July 2021: Lilly Research Award Program (LRAP): “The effects of ligand, genotype and tissue diversity on GIPR trafficking responses”. Co-Investigator (with Dr Ben Jones and Dr Kyle Sloop).

April 2021: BBSRC 20ALERT equipment grant: “Optical Fluorescence Micro and Nanoscopy to determine and quantify functional molecular interactions and dynamics across time and length scales”. Co-Investigator; Principal Investigator: Dr J. Bernardino de la Serna.

Jan 2021: Commonwealth PhD Scholarship: “Regulation of beta cell incretin responses by the lipid microenvironment” (Affiong Oqua). Sponsor/PI.

Jan 2021: DUK PhD Scholarship: “Spatiotemporal Control of Signaling of the GLP-1R Variant Ala316Thr in Pancreatic Beta Cells”. Principal Supervisor.

Dec 2019: EFSD/Boehringer Ingelheim European Research Programme on “Multi-System Challenges in Diabetes”: “Understanding the tissue-specific effects of biased GLP-1 receptor agonism in type 2 diabetes”. Co-Investigator; Principal Investigator: Dr B. Jones.

May 2019: Sun Pharmaceutical Industries: “Functional Studies on Novel GLP-1R Agonists”. Co- Investigator; Principal Investigator: Prof G.A. Rutter.

Mar 2018: MRC Project Grant: “Targeting GLP-1 Receptor Trafficking to Improve Therapies for Type 2 Diabetes”. Principal Investigator, grant number MR/R010676/1.

Sep 2016: DUK Early Career Small Grant: “Modulation of pancreatic beta-cell cytokine-induced apoptosis by p38-dependent ligand-independent activation of epidermal growth factor receptor”. Principal Investigator, grant number 16/0005441.

Mar 2015: MRC New Investigator Research Grant: “Role and regulation of GLP-1 receptor trafficking in pancreatic beta cells”. Principal Investigator, grant number MR/M012646.

Guest Lectures

Biased Signaling and Receptor Trafficking, The Latest on Incretin/GPCR Signaling in the Islet Symposium, American Diabetes Association 81st Scientific Sessions, Virtual, 2021

Glucagon-like peptide-1 receptor as a target in diabetes and obesity, Centre of Membrane Proteins and Receptors (COMPARE) Annual Research Symposium, University of Nottingham, UK, 2019

Targeting GLP-1 Receptor Trafficking to Improve Agonist Efficacy, American Diabetes Association 78th Scientific Sessions, Orlando, Florida, USA, 2018

Research Staff



Research Student Supervision

Buenaventura Perera,T, PhD title: "Regulation of GLP-1R Signalling by Endocytic Membrane Trafficking and its Significance for Pancreatic Beta Cell Insulin Secretion"

El Eid,L, PhD title: "The Spatiotemporal Control of Signalling and Trafficking of GLP-1R Variant Ala316Thr in Pancreatic Beta Cells"

Oqua,A, PhD title: "Regulation of beta cell incretin responses by the lipid microenvironment"