Summary
Dr Ashwin Venkataraman is an Old Age Psychiatrist (SpR) at South London and Maudsley NHS Trust. Before this he was an Alzheimer's Society Clinical Research Fellow at the UKDRI at Imperial College London undertaking his PhD in PET and MRI Imaging of the Cellular Phase of Alzheimer's Disease with Prof Paul Matthews. He was awarded the Advances in Alzheimer’s and Parkinson’s Therapies AD/PD Junior Faculty Award for this work.
His current research assesses the early changes in Alzheimer's disease by looking at cell stress, mitochondria, synapses and amyloid to understand the links between the underlying biology and the clinical expression of the disease. He also uses machine learning approaches to better optimise diagnosis, stratification and prediction of response to existing and novel therapies.
Prior to this he was an Alzheimer's Research UK Clinical Fellow at the Neuropsychopharmacology Unit at Imperial College London working on alcohol and amyloid deposition, and investigating a novel Imidazoline-2 receptor radioligand for Alzheimer's disease.
He is a Member of the Royal College of Psychiatrists. Before this he was an NIHR Academic Clinical Fellow, Academic Foundation Programme Doctor, and graduated from University College London Medical School.
Selected Publications
Journal Articles
Venkataraman AV, Bai W, Whittington A, et al., 2021, Boosting the diagnostic power of amyloid-β PET using a data-driven spatially informed classifier for decision support, Alzheimer's Research and Therapy, Vol:13, ISSN:1758-9193, Pages:1-12
Calsolaro V, Matthews PM, Donat CK, et al., 2021, Astrocyte reactivity with late onset cognitive impairment assessed in-vivo using 11C-BU99008 PET and its relationship with amyloid load, Molecular Psychiatry, ISSN:1359-4184
Young PNE, Estarellas M, Coomans E, et al., 2020, Imaging biomarkers in neurodegeneration: current and future practices, Alzheimer's Research and Therapy, Vol:12, ISSN:1758-9193, Pages:1-17
Suzuki H, Venkataraman AV, Bai W, et al., 2019, Associations of regional brain structural differences with aging, modifiable risk factors for dementia, and cognitive performance, Jama Network Open, Vol:2, ISSN:2574-3805, Pages:1-19
Venkataraman A, Mansur A, Lewis Y, et al., 2019, Evaluation of mitochondrial and synaptic function in Alzheimer’s disease (AD): a [18F]BCPP-EF, [11C]SA4503 and [11C]UCB-J PET study, Journal of Cerebral Blood Flow and Metabolism, Vol:39, ISSN:1559-7016, Pages:121-122
Venkataraman A, Keat N, Myers J, et al., 2018, First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site, Ejnmmi Research, Vol:8, ISSN:2191-219X
Edison P, Mayers J, Calsolaro V, et al., 2017, Dementia Platform U.K. Experimental medicine: human in vivo astroglial activation in early Alzheimer’s disease, Alzheimers & Dementia, Vol:13, ISSN:1552-5260, Pages:P1073-P1074
Venkataraman A, Kalk N, Sewell G, et al., 2016, Alcohol and Alzheimer's Disease-Does Alcohol Dependence Contribute to Beta-Amyloid Deposition, Neuroinflammation and Neurodegeneration in Alzheimer's Disease?, Alcohol and Alcoholism, Vol:52, ISSN:1464-3502, Pages:151-158
Chapters
Venkataraman A, Turton S, Lingford-Hughes A, 2020, Drug use and associated neuropsychiatric conditions, Oxford Textbook of Neuropsychiatry, Oxford University Press, ISBN:9780198757139
Venkataraman A, Perry R, Malhotra P, Young Onset Dementia