Summary
Dr Ahran Arnold MBBS BSc MSc MRCP PhD is an Academic Clinical Lecturer in Cardiovascular Sciences at the National Heart and Lung Institute (NHLI), Imperial College London (h-index ≥20) and a Specialist Registrar in Cardiac Electrophysiology, Complex Devices and Inherited Arrhythmia Syndromes at Hammersmith Hospital, Imperial College Healthcare NHS Trust.
He completed his undergraduate medical training at Imperial College London with numerous distinctions and merits in 2010 with an intercalated BSc in Neuroscience and Mental Health in 2008.
He undertook his post-registration general medical training from 2011-14 in London (Chelsea & Westminster Hospital, Royal Brompton Hospital, King's College Hospital) in General, Acute, Emergency and Intensive Care medicine, as well as Cardiology and Neurology, at tertiary and quaternary centres.
He wrote and published the medical education book "Differential Diagnosis for General Medicine" (Amazon) in 2014.
He completed his general cardiology training from 2014-16 at Royal Brompton Hospital and predominately at Hammersmith Hospital, Imperial College Healthcare NHS Trust alongside research training as an NIHR Academic Clinical Fellow in Cardiology at Imperial College London.
He completed a MSc in Health Economics, Outcomes and Management at the London School of Economics in association with the European Heart Academy with Merit in 2017.
He completed a PhD in 2020 at the NHLI, with a focus on development and mechanistic evaluation of innovations in complex cardiac device therapy (His bundle pacing, Cardiac Resynchronization Therapy, Sudden Cardiac Death risk stratification, left ventricular outflow tract obstruction modulation, machine learning and haemodynamic sensors).
He was appointed an Academic Clinical Lecturer and Post-Doctoral Research Fellow at NHLI in 2020 funded by the NHLI and the BHF Imperial Centre of Research Excellence alongside completing his sub-specialty training in Complex Devices, Invasive Electrophysiology and Inherited Cardiac Conditions at Hammersmith Hospital. In 2022, he was appointed to an NIHR Academic Clinical Lectureship to continue his work.
He is the module lead for the Clinical Research and Innovation module for Year 2 medical students at Imperial College London.
He was a lecturer and examiner for the University of Buckingham Clinical MD in General Internal Medicine (website).
He is a peer-reviewer for the following publications: BMJ, EHJ, JACC:EP, AER, JCE, PACE, HF reviews and has been grant reviewer for ESPRC, NIHR and BHF among others. He is a Review Editor for Frontiers in Physiology and has been a topic editor for Frontiers in Cardiovascular Medicine.
Funding Awarded
"Unmasking concealed arrhythmia syndromes" FS/CRTF/23/24482 - Co-Applicant - BHF Clinical Research Training Fellowship: K Sales - February 2024 - £345,619.37
"Personalising Rhythm management using AI enabled Clothing Technology with Integrated Sensors" - Primary Applicant (clinical) - Innovate UK Advancing Prediction Medicine - £875,939.00
"Novel solutions to the challenges in implantation and follow-up of conduction system pacing" FS/CRTF/23/24417 - Co-Applicant - BHF Clinical Research Training Fellowship: A Naraen - May 2023 - £315,035.12
"Mechanisms and innovations in right ventricular pacing for hypertrophic cardiomyopathy" FS/CRTF/21/24171 - Co-Applicant - BHF Clinical Research Training Fellowship: JS Mohal - July 2021 - £279,826.08
"Mechanisms and innovations in right ventricular pacing for hypertrophic cardiomyopathy" RFPR2122_22 - Co-Applicant - Imperial Healthcare Charity Fellowship: JS Mohal - April 2021 - £65,000.00
Post-Doctoral Research Fellowship RE/18/4/34215 - Applicant - British Heart Foundation Imperial Centre of Research Excellence - £40,000.00
"Development of physiological biomarkers for implantable cardioverter defibrillators to allow patient specific therapies, in order to improve outcomes" P74166 - Co-Applicant - NIHR Imperial Biomedical Research Centre Project Award - April 2018 - £206,924.00
Videos
Interview with HRStv 2020 (highest scoring digital health abstract)
Machine learning for His bundle pacing
Interview with TouchCardio 2019 (young investigator award runner-up)
His bundle pacing for LBBB
Awards and Prizes
Heart Rhythm Society (HRS) Highest Scoring Fellow Abstract - Winner (2021)
European Heart Rhythm Association (EHRA) Young Investigator Award - Finalist (2021)
European Heart Rhythm Association (EHRA) best of e-cardiology abstract - Supervisor of Winner - CP Chan (2021)
Heart Rhythm Society (HRS) Highest Scoring Digital Health Abstract - Winner (2020)
European Heart Journal: Quality of Care and Clinical Outcomes (EHJ:QCCO) - most downloaded article (2019)
3rd Physiology of Pacing Symposium (PPS3) - Best Abstract - 2nd place (2019)
3rd Physiology of Pacing Symposium (PPS3) - Travel Scholarship - Winner (2019)
National Heart and Lung Institute (NHLI) - Best Clinical Oral Presentation (2019)
EHRA-certified Cardiac Device Specialist - Level 1 (2019)
European Heart Rhythm Association (EHRA) Young Investigator Award - 2nd place (2019)
European Heart Rhythm Association (EHRA) Innovation Award - Semi-Finalist (2019)
Venture Catalyst Challenge Innovation Award - Semi-Finalist (2019)
European Heart Rhythm Association (EHRA) Congress Travel Award - Winner (2019)
Royal Society of Medicine (RSM) President's Medal for Cardiovascular Research - Winner (2018)
MSc Health Economics, Outcomes and Management, London School of Economics (LSE) - Merit (2017)
Academic Clinical Fellowship in Cardiology (2014)
London Deanery Excellence in Leadership Award (2012)
MBBS Finals Medicine and Surgery, Imperial College London - Merit (2010)
MBBS Finals Obstetrics, Gynaecology, Psychiatry, Imperial College London - Distinction (2009)
BSc Neuroscience and Mental Health, Imperial College London - Upper Second Class Honours (2008)
Selected Publications
Journal Articles
Arnold A, Howard J, Chiew K, et al., 2019, Right ventricular pacing for hypertrophic obstructive cardiomyopathy: meta-analysis and meta-regression of clinical trials, European Heart Journal - Quality of Care and Clinical Outcomes, Vol:5, ISSN:2058-5225, Pages:321-333
Keene D, Shun-Shin M, Arnold A, et al., 2019, Quantification of Electromechanical Coupling to Prevent Inappropriate Implantable Cardioverter-Defibrillator Shocks, Jacc: Clinical Electrophysiology, Vol:5, ISSN:2405-500X, Pages:705-715
Howard J, Fisher L, Shun-Shin M, et al., 2019, Cardiac rhythm device identification using neural networks, Jacc: Clinical Electrophysiology, Vol:5, ISSN:2405-5018, Pages:576-586
Arnold AD, Vijayaraman P, 2019, His bundle pacing: The road ahead: An editorial commentary on “Updates on His Bundle Pacing: The Road More Traveled Lately” by Fatima M Ezzeddine MD & Gopi Dandamudi MD FHRS, Trends in Cardiovascular Medicine, ISSN:1050-1738
Arnold A, Shun-Shin M, Keene D, et al., 2018, His resynchronization versus biventricular pacing in patients with heart failure and left bundle branch block, Journal of the American College of Cardiology, Vol:72, ISSN:0735-1097, Pages:3112-3122
Keene D, Arnold A, Shun-Shin MJ, et al., 2018, Rationale and design of the randomized multicentre His Optimized Pacing Evaluated for Heart Failure (HOPE-HF) trial, Esc Heart Failure, Vol:5, ISSN:2055-5822, Pages:965-976
Sharma PS, Naperkowski A, Bauch TD, et al., 2018, Permanent His Bundle Pacing for Cardiac Resynchronization Therapy in Patients With Heart Failure and Right Bundle Branch Block, Circulation-Arrhythmia and Electrophysiology, Vol:11, ISSN:1941-3149
Murray MI, Arnold A, Younis M, et al., 2018, Cryoballoon versus radiofrequency ablation for paroxysmal atrial fibrillation: a meta-analysis of randomized controlled trials, Clinical Research in Cardiology, Vol:107, ISSN:1861-0684, Pages:658-669
Ali N, Keene D, Arnold A, et al., 2018, His bundle pacing: a new frontier in the treatment of heart failure, Arrhythmia & Electrophysiology Review, Vol:7, ISSN:2050-3369, Pages:103-110
Ahmad Y, Howard J, Arnold A, et al., 2018, Patent foramen ovale closure versus medical therapy for cryptogenic stroke: a meta-analysis of randomised controlled trials, European Heart Journal, Vol:39, ISSN:1522-9645, Pages:1638-1649
Ahmad Y, Demir O, Rajkumar CA, et al., 2018, Optimal antiplatelet strategy after transcatheter aortic valve implantation: a meta-analysis, Open Heart, Vol:5, ISSN:2053-3624