Imperial College London
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DrAhranArnold

Faculty of Medicine, National Heart & Lung Institute

Clinical Senior Lecturer in Cardiology
 
 
 
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Contact

 

ahran.arnold

 
 
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Location

 

Fellows' RoomBlock B Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Arnold:2020:10.15420/aer.2020.14,
author = {Arnold, AD and Whinnett, Z and Vijayaraman, P},
doi = {10.15420/aer.2020.14},
journal = {Arrhythmia & Electrophysiology Review},
pages = {136--145},
title = {His-Purkinje conduction system pacing: state of the art in 2020},
url = {http://dx.doi.org/10.15420/aer.2020.14},
volume = {9},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Conduction system pacing involves directly stimulating the specialised His–Purkinje cardiac conduction system with the aim of activating the ventricles physiologically, in contrast to the dyssynchronous activation produced by conventional myocardial pacing. Since the first report of permanent His bundle pacing (HBP) in 2000, the stylet-driven technique of its earliest incarnation has been superseded by a more successful stylet-less approach. Widespread uptake has led to a much greater evidence base. Single-centre observational studies have now been supported by large multicentre, international registries, mechanistic studies and the first randomised controlled trials. New evidence has elucidated mechanisms of HBP and illustrated the nature and magnitude of its potential benefits for preventing pacing-induced cardiomyopathy and correcting bundle branch block. Left bundle branch pacing (LBBP) is a newer technique in which the lead is fixed deep into the left side of the intraventricular septum to allow capture of the left bundle, distal to the His bundle. LBBP holds promise as a method for physiological pacing that overcomes some of the fixation, threshold and sensing challenges of HBP. In this state-of-the-art review of His–Purkinje conduction system pacing, the authors assess recent evidence and current practice and explore emerging and future directions in this rapidly evolving field.
AU  - Arnold,AD
AU  - Whinnett,Z
AU  - Vijayaraman,P
DO  - 10.15420/aer.2020.14
EP  - 145
PY  - 2020///
SN  - 2050-3369
SP  - 136
TI  - His-Purkinje conduction system pacing: state of the art in 2020
T2  - Arrhythmia & Electrophysiology Review
UR  - http://dx.doi.org/10.15420/aer.2020.14
UR  - https://www.aerjournal.com/articles/his-purkinje-conduction-system-pacing-state-art-2020
UR  - http://hdl.handle.net/10044/1/103144
VL  - 9
ER  -
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