Imperial College London

Dr Alex Ivanov

Faculty of Natural SciencesDepartment of Chemistry

Junior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 3156alex.ivanov Website

 
 
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Assistant

 

Mr John Murrell +44 (0)20 7594 2845

 
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Location

 

6.40Flowers buildingSouth Kensington Campus

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Summary

 

Summary

Dr Ivanov's research is focused on the innovation of nanopore sensors and platforms for single-molecule detection and delivery, which enable the studying of fundamentally important molecules in chemistry, biology and medicine. Examples include tunnelling nanopore platform for high-resolution DNA fragment sizing and sequencing applications (Nano Lett 2011, 11), development of methods for high precision fabrication and positioning of nanoelectrodes in a nanopore (ACS Nano 2014, 8), optical/plasmonic nanopore platforms (Nano Lett 2013 13(10)); (Nano Lett 2015 15(1)); ACS Nano 2015, 9(2), integrated nanopipette microfluidic platforms Anal Chem 2013 86(1), Anal Chem 2014, 86(3), methods for on-demand delivery of single biological molecules (ACS Nano 2015, 9(4)) and single molecule detection from ultra-dilute samples using molecular traps (Nature Comm, 2016, 7) and recently detection of proteins linked to neurodegenerative diseases.


Research Interests:

Nanopore platforms, DNA sequencing

Single molecule delivery and detection (nucleic acids and proteins)

label free detection of proteins linked to neurodegenerative disease (alpha synuclein, amyloid beta, tau)

Alex's research publications can be found at the tab above, or on GoogleScholar


Research Highlights:

High-throughput Molecular Detection

Imperial College Website, Nanowerk

DNA Tunneling Detector 

Imperial College Website,  Nanowerk


Selected Publications

Journal Articles

Freedman KJ, Otto LM, Ivanov AP, et al., 2016, Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping, Nature Communications, Vol:7, ISSN:2041-1723, Pages:10217-10217

Ivanov AP, Actis P, Jonsson P, et al., 2015, On-Demand Delivery of Single DNA Molecules Using Nanopipets, ACS Nano, Vol:9, ISSN:1936-0851, Pages:3587-3595

Pitchford WH, Kim H-J, Ivanov AP, et al., 2015, Synchronized Optical and Electronic Detection of Biomolecules Using a Low Noise Nanopore Platform, ACS Nano, Vol:9, ISSN:1936-0851, Pages:1740-1748

Crick CR, Albella P, Ng B, et al., 2015, Precise Attoliter Temperature Control of Nanopore Sensors Using a Nanoplasmonic Bullseye, Nano Letters, Vol:15, ISSN:1530-6984, Pages:553-559

Ivanov AR, Freedman KJ, Kim MJ, et al., 2014, High Precision Fabrication and Positioning of Nanoelectrodes in a Nanopore, ACS Nano, Vol:8, ISSN:1936-0851, Pages:1940-1948

Ivanov AP, Instuli E, McGilvery CM, et al., 2011, DNA tunneling detector embedded in a nanopore, Nano Letters, Vol:11, ISSN:1530-6984, Pages:279-285

Miles BN, Ivanov AP, Wilson KA, et al., 2013, Single molecule sensing with solid-state nanopores: novel materials, methods, and applications, Chemical Society Reviews, Vol:42, ISSN:0306-0012, Pages:15-28

Cecchini MP, Wiener A, Turek VA, et al., 2013, Rapid Ultrasensitive Single Particle Surface-Enhanced Raman Spectroscopy Using Metallic Nanopores, Nano Letters, Vol:13, ISSN:1530-6984, Pages:4602-4609

More Publications