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BibTex format

@article{Ren:2020:10.1002/smtd.202000356,
author = {Ren, R and Wang, X and Cai, S and Korchev, Y and Ivanov, A and Edel, J},
doi = {10.1002/smtd.202000356},
journal = {Small Methods},
pages = {1--8},
title = {Selective sensing of proteins using aptamer functionalised nanopore extended field-effect transistors},
url = {http://dx.doi.org/10.1002/smtd.202000356},
volume = {4},
year = {2020}
}

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TY  - JOUR
AB  - The ability to sense proteins and proteinrelated interactions at the singlemolecule level is becoming of increasing importance to understand biological processes and diseases better. Singlemolecule sensors, such as nanopores have shown substantial promise for the labelfree detection of proteins; however, challenges remain due to the lack of selectivity and the need for relatively high analyte concentrations. An aptamerfunctionalized nanopore extended fieldeffect transistor (nexFET) sensor is reported here, where protein transport can be controlled via the gate voltage that in turn improves singlemolecule sensitivity and analyte capture rates. Importantly, these sensors allow for selective detection, based on the choice of aptamer chemistry, and can provide a valuable addition to the existing methods for the analysis of proteins and biomarkers in biological fluids.
AU  - Ren,R
AU  - Wang,X
AU  - Cai,S
AU  - Korchev,Y
AU  - Ivanov,A
AU  - Edel,J
DO  - 10.1002/smtd.202000356
EP  - 8
PY  - 2020///
SN  - 2366-9608
SP  - 1
TI  - Selective sensing of proteins using aptamer functionalised nanopore extended field-effect transistors
T2  - Small Methods
UR  - http://dx.doi.org/10.1002/smtd.202000356
UR  - https://onlinelibrary.wiley.com/doi/10.1002/smtd.202000356
UR  - http://hdl.handle.net/10044/1/81206
VL  - 4
ER  -

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Dr Alex Ivanov

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